All Outputs (667)

Kamin blocking is associated with reduced medial-frontal gyrus activation: implications for prediction error abnormality in schizophrenia (2012)
Journal Article

The following study used 3-T functional magnetic resonance imaging (fMRI) to investigate the neural signature of Kamin blocking. Kamin blocking is an associative learning phenomenon seen where prior association of a stimulus (A) with an outcome block... Read More about Kamin blocking is associated with reduced medial-frontal gyrus activation: implications for prediction error abnormality in schizophrenia.

The multi-kinase inhibitor TG02 overcomes signalling activation by survival factors to deplete MCL1 and XIAP and induce cell death in primary acute myeloid leukaemia cells (2012)
Journal Article

The novel multi-kinase inhibitor TG02 has selectivity against cell cycle and transcriptional cyclin dependent kinases (CDKs) as well as fms-like tyrosine kinase receptor-3 (FLT3). Inhibition of transcriptional CDKs preferentially depletes short-lived... Read More about The multi-kinase inhibitor TG02 overcomes signalling activation by survival factors to deplete MCL1 and XIAP and induce cell death in primary acute myeloid leukaemia cells.

A mental disorder of a kind or degree warranting confinement: examining justifications for psychiatric detention (2012)
Journal Article

It has long been the case in jurisprudence under the European Convention on Human Rights that mental disorder must be of a certain severity in order to justify detention, but there has been little meaningful debate as to what that means. The questio... Read More about A mental disorder of a kind or degree warranting confinement: examining justifications for psychiatric detention.

Towards an organizational perspective on party funding: explaining financial transfers from MEPs to their national parties (2012)
Journal Article

Which European Parliament (EP) parties are able to extract regular donations from their MEPs' salaries and if they extract donations how great are they? In the literature on party finances, there has been a lack of attention paid to the use of salari... Read More about Towards an organizational perspective on party funding: explaining financial transfers from MEPs to their national parties.

Neural and Vascular Responses to Fused Binocular Stimuli: A VEP and fNIRS Study (2012)
Journal Article

Purpose.: The aim of our study was to investigate the correlation between neural and hemodynamic responses to stereoscopic stimuli recorded over visual cortex. Methods.: Test stimuli consisted of a static checkerboard (checks) and dichoptic stati... Read More about Neural and Vascular Responses to Fused Binocular Stimuli: A VEP and fNIRS Study.

Mechanical characterisation of reclaimed asphalt mixes for modelling purposes (2012)
Presentation / Conference

Reclaimed Asphalt (RA) is a 100% recyclable material, but at present in Europe the re-use of RA in mixes is limited and a huge amount of it is simply wasted. Furthermore, the recycling of asphalt often involves a certain downgrading of the material.... Read More about Mechanical characterisation of reclaimed asphalt mixes for modelling purposes.

High reward makes items easier to remember, but harder to bind to a new temporal context (2012)
Journal Article

Learning through reward is central to adaptive behavior. Indeed, items are remembered better if they are experienced while participants expect a reward, and people can deliberately prioritize memory for high- over low-valued items. Do memory advantag... Read More about High reward makes items easier to remember, but harder to bind to a new temporal context.

The diversity of Class II transposable elements in mammalian genomes has arisen from ancestral phylogenetic splits during ancient waves of proliferation through the genome (2012)
Journal Article

DNA transposons make up three percent of the human genome, roughly the same percentage as genes. However, due to their inactivity, they are often ignored in favour of the more abundant, active, retroelements. Despite this relative ignominy, there are... Read More about The diversity of Class II transposable elements in mammalian genomes has arisen from ancestral phylogenetic splits during ancient waves of proliferation through the genome.

Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties (2012)
Journal Article

BACKGROUND The use of personal computers (PCs) and the Internet to provide health care information and interventions has increased substantially over the past decade. Yet the effectiveness of such an approach is highly dependent upon whether the t... Read More about Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties.

Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces (2012)
Journal Article

Designing materials to control biology is an intense focus of biomaterials and regenerative medicine research. Discovering and designing materials with appropriate biological compatibility or active control of cells and tissues is being increasingly... Read More about Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces.

A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity (2012)
Journal Article

The opportunistic human pathogen, Pseudomonas aeruginosa, is a major cause of infections in chronic wounds, burns and the lungs of cystic fibrosis patients. The P. aeruginosa genome encodes at least three proteins exhibiting the characteristic three... Read More about A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity.

The role of roles: Physical cooperation between humans and robots (2012)
Journal Article

Since the strict separation of working spaces of humans and robots has experienced a softening due to recent robotics research achievements, close interaction of humans and robots comes rapidly into reach. In this context, physical human–robot intera... Read More about The role of roles: Physical cooperation between humans and robots.

The myogenic regulatory factors: critical determinants of muscle identity in development, growth and regeneration (2012)
Book Chapter

Does returning sites of historic peri-urban waste disposal to vegetable production pose a risk to human health? - A case study near Manchester, UK (2012)
Journal Article

Urban waste disposal occurred on fenland to the west of Manchester, England, between 1900 and 1964. The reclaimed fenland, Chat Moss, is now used for mixed arable farming. A total of 1.92 Mt of waste including privy midden, street sweepings, clinkers... Read More about Does returning sites of historic peri-urban waste disposal to vegetable production pose a risk to human health? - A case study near Manchester, UK.

The weight and breadth of evidence: Some reflections on the strengths of international education and development research (2012)
Journal Article

Editorial in which I consider the strengths of the international and comparative education research tradition in the face of the "evidence based turn".

Thermal, mechanical and microstructural analysis of concrete containing microencapsulated phase change materials (2012)
Journal Article

This paper studies the thermal, mechanical and microstructural aspects of concrete containing different amounts of microencapsulated phase change materials (PCMs). In addition, numerical simulation is carried out to study the potential application of... Read More about Thermal, mechanical and microstructural analysis of concrete containing microencapsulated phase change materials.

Twist deformations of module homomorphisms and connections (2012)
Journal Article

Let H be a Hopf algebra, A a left H-module algebra and V a left H-module A-bimodule. We study the behavior of the right A-linear endomorphisms of V under twist deformation. We in particular construct a bijective quantization map to the right A_\star-... Read More about Twist deformations of module homomorphisms and connections.

Combinatorial discovery of polymers resistant to bacterial attachment (2012)
Journal Article

Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal performance of medical devices. In this study, we determined the attachment of selected bacterial species to hundreds of polymeric materials in a high-throughput... Read More about Combinatorial discovery of polymers resistant to bacterial attachment.

The intergalactic medium thermal history at redshift z = 1.7–3.2 from the Lyα forest: a comparison of measurements using wavelets and the flux distribution (2012)
Journal Article

We investigate the thermal history of the intergalactic medium (IGM) in the redshift interval z = 1.7–3.2 by studying the small-scale fluctuations in the Lyman α forest transmitted flux. We apply a wavelet filtering technique to 18 high-resolution qu... Read More about The intergalactic medium thermal history at redshift z = 1.7–3.2 from the Lyα forest: a comparison of measurements using wavelets and the flux distribution.

A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt (2012)
Journal Article

The surface epithelium lining the intestinal tract renews itself rapidly by a coordinated programme of cell proliferation, migration and differentiation events that is initiated in the crypts of Lieberkühn. It is generally believed that colorectal ca... Read More about A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt.