All Outputs (668)

Development of a poststroke checklist to standardize follow-up care for stroke survivors (2012)
Journal Article

Background: Long-termcare for stroke survivors is fragmented and lacks an evidence-based, easy-to-use tool to identify persistent long-term problems among stroke survivors and streamline referral for treatment. We sought to develop a poststroke check... Read More about Development of a poststroke checklist to standardize follow-up care for stroke survivors.

Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray (2012)
Journal Article

Background Papaya (Carica papaya L.) is a commercially important crop that produces climacteric fruits with a soft and sweet pulp that contain a wide range of health promoting phytochemicals. Despite its importance, little is known about transcrip... Read More about Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray.

Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem (2012)
Journal Article

Background and Purpose Prokineticin 2 (PK2) has recently been shown to acutely reduce food intake in rodents. We aimed to determine the CNS sites and receptors that mediate the anorectic effects of peripherally administered PK2 and its chronic effect... Read More about Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem.

The socio-technical organisation of community pharmacies as a factor in the Electronic Prescription Service Release Two implementation: a qualitative study (2012)
Journal Article

Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial (2012)
Journal Article

Background Electronic monitoring of inhaled asthma medications is one method to measure medication adherence and patterns of use. Information on the performance of monitors in a randomized controlled trial allows researchers and clinicians to unde... Read More about Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial.

A neural network approach to predicting price negotiation outcomes in business-to-business contexts (2012)
Journal Article

Price premiums are a key profit driver for long-term business relationships. For sellers in business-to-business (B2B) relationships, it is important to have appropriate strategies to negotiate price increases without trading off the relationships wi... Read More about A neural network approach to predicting price negotiation outcomes in business-to-business contexts.

Soft-bound synaptic plasticity increases storage capacity (2012)
Journal Article

Accurate models of synaptic plasticity are essential to understand the adaptive properties of the nervous system and for realistic models of learning and memory. Experiments have shown that synaptic plasticity depends not only on pre- and post-synapt... Read More about Soft-bound synaptic plasticity increases storage capacity.

What do we mean by wet? Geoarchaeology and the reconstruction of water availability (2012)
Journal Article

Geoarchaeology has a key role to play in the human-climate-environment debate, including research into the controls and variability of water availability. However its interdisciplinarity can cause complications as well as advantages and leads to conf... Read More about What do we mean by wet? Geoarchaeology and the reconstruction of water availability.

Can GPs working in secure environments in England re-license using the Royal College of General Practitioners revalidation proposals? (2012)
Journal Article

Background Revalidation for UK doctors is expected to be introduced from late 2012. For general practitioners (GPs), this entails collecting supporting information to be submitted and assessed in a revalidation portfolio every five years. The aim of... Read More about Can GPs working in secure environments in England re-license using the Royal College of General Practitioners revalidation proposals?.

Medieval business networks: St Mary's guild and the borough court in later medieval Nottingham (2012)
Journal Article

Historians have suggested that medieval urban guilds played a role in political and commercial networking. Guilds' commercial protectionism was designed to benefit their membership and close ties have been discovered between merchant guilds and urban... Read More about Medieval business networks: St Mary's guild and the borough court in later medieval Nottingham.

The visualised foetus: A cultural and political analysis of ultrasound imagery (2012)
Book

© 2012 Julie Roberts. All rights reserved. The latest three- and four dimensional images produced by modern ultrasound technology offer strikingly realistic representations of the foetus - representations that have further transformed experiences of... Read More about The visualised foetus: A cultural and political analysis of ultrasound imagery.

Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition (2012)
Journal Article

INTRODUCTION Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted agents. We present comprehensive characterization of tumor aggregates generated... Read More about Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition.

Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study (2012)
Journal Article

Background 10-15% of students struggle at some point in their medicine course. Risk factors include weaker academic qualifications, male gender, mental illness, UK ethnic minority status, and poor study skills. Recent research on an undergraduate... Read More about Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study.

The cosmology of the Fab-Four (2012)
Journal Article

We have recently proposed a novel self tuning mechanism to alleviate the famous cosmological constant problem, based on the general scalar tensor theory proposed by Horndeski. The self-tuning model ends up consisting of four geometric terms in the ac... Read More about The cosmology of the Fab-Four.

Click chemistry in carbon nanoreactors (2012)
Journal Article

Copper-nanoparticle catalytic centres anchored at the 5 graphitic step-edges within hollow carbon nanoreactors exhibit superior activity and stability in cycloaddition reactions as compared to catalytic centres outside the nanoreactors. Nanoscale con... Read More about Click chemistry in carbon nanoreactors.

Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator (2012)
Journal Article

In the skeletal system glucose serves as an essential source of energy for the development, growth, and maintenance of bone and articular cartilage. It is particularly needed for skeletal morphogenesis during embryonic growth and fetal development. G... Read More about Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator.

An innovative psychometric solar-powered water desalination system (2012)
Journal Article

Important advances have been made in solar water desalination technology but their wide application is restricted by relatively high capital and running costs. Until recently, solar concentrator collectors had usually been employed to distill water i... Read More about An innovative psychometric solar-powered water desalination system.

A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium (2012)
Journal Article

Background: Lymphovascular invasion (LVI) is an important step in the metastatic cascade; tumor cell migration and adhesion to blood and lymphatic vessels is followed by invasion through the vessel wall and subsequent systemic spread. Although prim... Read More about A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium.

Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage (2012)
Journal Article

The initiation of lens cataract has long been associated with the development of a membrane "leak" in lens fiber cells that depolarizes the lens intracellular potential and elevates intracellular Na+ and Ca2+ concentrations. It has been proposed that... Read More about Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage.

The “Sharp” blade against HIF-mediated metastasis (2012)
Journal Article

Hypoxia-inducible factors (HIFs) control cellular adaptation to oxygen deprivation. Cancer cells engage HIFs to sustain their growth in adverse conditions, thus promoting a cellular reprograming that includes metabolism, proliferation, survival and m... Read More about The “Sharp” blade against HIF-mediated metastasis.