All Outputs (691)

Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin (2012)
Journal Article
Morgan, G. T., Jones, P., & Bellini, M. (2012). Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin. Chromosome Research, 20(8), https://doi.org/10.1007/s10577-012-9324-x

We have investigated the association of DNA methylation and proteins interpreting methylation state with the distinctive closed and open chromatin structural domains that are directly observable in the lampbrush chromosomes (LBCs) of amphibian oocyte... Read More about Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin.

Decoding Learning: The Proof, Promise and Potential of Digital Education (2012)
Report
Luckin, R., Bligh, B., Crook, C., Ainsworth, S., & Manches, A. (2012). Decoding Learning: The Proof, Promise and Potential of Digital Education. London: Nesta

The recent Decoding Learning study seeks to pinpoint innovative practice by teachers and students when it comes to exploiting technology in education. It offers eight approaches to innovation with ICT. Professor Rosemary Luckin explains.

Dairy herd health (2012)
Book
Green, M., Bradley, A., Breen, J., Green, L., Hayton, A., Higgins, H., Hudson, C., Huxley, J., & Statham, J. (Eds.). (2012). Dairy herd health. CABI

Dairy herd health is an important and universal topic in large animal veterinary practice and farming, covering both preventive medicine and health promotion. With the move towards large-scale farming, the health of the herd is important as an econom... Read More about Dairy herd health.

Managing herd reproduction (2012)
Book Chapter
Hudson, C., Kerby, M., Statham, J., & Wapenaar, W. (2012). Managing herd reproduction. In Dairy herd health (73-116). CAB International

Pavel Stroilov, "Behind the Desert Storm: a secret archive stolen from the Kremlin that sheds new light on the Arab revolutions in the Middle East" (2012)
Journal Article
Sergey, R. (2012). Pavel Stroilov, "Behind the Desert Storm: a secret archive stolen from the Kremlin that sheds new light on the Arab revolutions in the Middle East". Journal of Cold War Studies, 14(4),

The article reviews the book "Behind the Desert Storm: a secret archive stolen from the Kremlin that sheds new light on the Arab revolutions in the Middle East" by Pavel Stroilov.

Asymptotically optimal quantum channel reversal for qudit ensembles and multimode Gaussian states (2012)
Journal Article
Bowles, P., Guţă, M., & Adesso, G. (2012). Asymptotically optimal quantum channel reversal for qudit ensembles and multimode Gaussian states. New Journal of Physics, 14, Article 113041. https://doi.org/10.1088/1367-2630/14/11/113041

We investigate the problem of optimally reversing the action of an arbitrary quantum channel C which acts independently on each component of an ensemble of n identically prepared d-dimensional quantum systems. In the limit of large ensembles, we cons... Read More about Asymptotically optimal quantum channel reversal for qudit ensembles and multimode Gaussian states.

Decisions for others become less impulsive the further away they are on the family tree (2012)
Journal Article
Ziegler, F. V., & Tunney, R. J. (2012). Decisions for others become less impulsive the further away they are on the family tree. PLoS ONE, 7(11), Article e49479. https://doi.org/10.1371/journal.pone.0049479

People tend to prefer a smaller immediate reward to a larger but delayed reward. Although this discounting of future rewards is often associated with impulsivity, it is not necessarily irrational. Instead it has been suggested that it reflects the de... Read More about Decisions for others become less impulsive the further away they are on the family tree.

Nonlinear modal coupling in a high-stress doubly-clamped nanomechanical resonator (2012)
Journal Article
Lulla, K., Cousins, R., Venkatesan, A., Patton, M., Armour, A., Mellor, C. J., & Owers-Bradley, J. (2012). Nonlinear modal coupling in a high-stress doubly-clamped nanomechanical resonator. New Journal of Physics, 14, Article 113040. https://doi.org/10.1088/1367-2630/14/11/113040

We present results from a study of the nonlinear inter-modal coupling between different flexural vibrational modes of a single high-stress, doubly-clamped silicon nitride nanomechanical beam. Using the magnetomotive technique and working at 100 mK we... Read More about Nonlinear modal coupling in a high-stress doubly-clamped nanomechanical resonator.

Isolation and characterization of oil bodies from Oryza sativa bran and studies of their physical properties (2012)
Journal Article
Nantiyakul, N., Furse, S., Fisk, I. D., Tucker, G., & Gray, D. A. (2013). Isolation and characterization of oil bodies from Oryza sativa bran and studies of their physical properties. Journal of Cereal Science, 57(1), 141-145. https://doi.org/10.1016/j.jcs.2012.11.002

In this paper, we demonstrate a novel and environmentally-conscious approach to the isolation of oil bodies (OBs) from the bran arising from the milling of Oryza sativa (Basmati rice). We have used several physical techniques to determine the effect... Read More about Isolation and characterization of oil bodies from Oryza sativa bran and studies of their physical properties.

Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: Self-reporting scaffolds for application in tissue engineering (2012)
Journal Article
Harrington, H. C., Rose, F. R., Reinwald, Y., Buttery, L. D., Ghaemmaghami, A. M., & Aylott, J. W. (2013). Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: Self-reporting scaffolds for application in tissue engineering. Analytical Methods, 5(1), 68-71. https://doi.org/10.1039/c2ay25771h

Ratiometric analyte responsive nanosensors have been incorporated into electrospun poly(lactic-co-glycolic) acid (PLGA) fibres to create self-reporting scaffolds. It has been demonstrated that the self-reporting scaffolds could be utilised to monitor... Read More about Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: Self-reporting scaffolds for application in tissue engineering.

Academic patenting: the importance of industry support (2012)
Journal Article
Lawson, C. (2013). Academic patenting: the importance of industry support. Journal of Technology Transfer, 36(4), https://doi.org/10.1007/s10961-012-9266-7

This paper provides evidence that university-industry collaboration is important for turning commercial opportunities into patents. The results suggest that researchers who receive a large share of research grants from industry have a higher propensi... Read More about Academic patenting: the importance of industry support.

Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129 (2012)
Journal Article
Six, J. S., Hughes-Riley, T., Stupic, K. F., Pavlovskaya, G. E., & Meersmann, T. (2012). Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129. PLoS ONE, 7(11), Article e49927. https://doi.org/10.1371/journal.pone.0049927

yperpolarized (hp) 129Xe and hp 83Kr for magnetic resonance imaging (MRI) are typically obtained through spin-exchange
optical pumping (SEOP) in gas mixtures with dilute concentrations of the respective noble gas. The usage of dilute noble gases mix... Read More about Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129.

Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria (2012)
Journal Article
Hobley, L., Lerner, T. R., Williams, L. E., Lambert, C., Till, R., Milner, D. S., Basford, S. M., Capeness, M. J., Fenton, A. K., Atterbury, R. J., Harris, M. A., & Sockett, R. E. (2012). Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria. BMC Genomics, 13(670), https://doi.org/10.1186/1471-2164-13-670

Background:

Evolution equipped Bdellovibrio bacteriovorus predatory bacteria to invade other bacteria, digesting and replicating, sealed within them thus preventing nutrient-sharing with organisms in the surrounding environment. Bdellovibrio were... Read More about Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria.

Ethnobiology: The missing link in ecology and evolution (2012)
Journal Article
Saslis-Lagoudakis, C. H., & Clarke, A. C. (2013). Ethnobiology: The missing link in ecology and evolution. Trends in Ecology and Evolution, 28(2), 67-68. https://doi.org/10.1016/j.tree.2012.10.017

Evolutionary biologists and ecologists increasingly appreciate the value of local knowledge of human communities for research into the past, present, and future of biodiversity. However, there are often significant problems accessing and interpreting... Read More about Ethnobiology: The missing link in ecology and evolution.

Inclusion in a South African high school? Reporting and reflecting on what learners say (2012)
Journal Article
Walton, E. (2013). Inclusion in a South African high school? Reporting and reflecting on what learners say. International Journal of Inclusive Education, 17(11), 1171-1185. https://doi.org/10.1080/13603116.2012.742577

A concern with formal and epistemological access to schools can neglect the importance of access to the informal school and the friendships and sense of belonging that this implies. Despite the challenges of voice research, listening to what young pe... Read More about Inclusion in a South African high school? Reporting and reflecting on what learners say.

Herbert Hill and the Federal Bureau of Investigation (2012)
Journal Article
Phelps, C. (2012). Herbert Hill and the Federal Bureau of Investigation. Labor History, 53(4), https://doi.org/10.1080/0023656X.2012.732757

This article points to previously undetected evidence demonstrating that Herbert Hill, labor director of the National Association for the Advancement of Colored People (NAACP) from the 1950s to the 1970s, informed for the Federal Bureau of Investigat... Read More about Herbert Hill and the Federal Bureau of Investigation.

Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007 (2012)
Journal Article
Jack, R. H., Konfortion, J., Coupland, V. H., Kocher, H. M., Berry, D. P., Allum, W., Linklater, K. M., & Møller, H. (2013). Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007. Cancer Epidemiology, 37(1), 34-38. https://doi.org/10.1016/j.canep.2012.10.008

Background: The patterns of primary liver cancer incidence and survival are not known for detailed ethnic groups within the UK.

Methods: Data on patients resident in England diagnosed with primary liver cancer (ICD-10 C22) between 2001 and 2007 w... Read More about Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007.

Bridging the gap: bitopic ligands of G-protein-coupled receptors (2012)
Journal Article
Lane, J. R., Sexton, P. M., & Christopoulos, A. (2013). Bridging the gap: bitopic ligands of G-protein-coupled receptors. Trends in Pharmacological Sciences, 34(1), 59-66. https://doi.org/10.1016/j.tips.2012.10.003

Although classical approaches to G-protein-coupled receptor (GPCR) drug design have targeted the orthosteric binding site, potentially all GPCRs possess druggable allosteric sites. In addition, it is clear that GPCRs can adopt multiple active states... Read More about Bridging the gap: bitopic ligands of G-protein-coupled receptors.

Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway (2012)
Journal Article
Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., LOURDUSAMY, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. .., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R., …Lovestone, S. (2014). Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry, 19(1), 88-98. https://doi.org/10.1038/mp.2012.163

Although the mechanism of Abaction in the pathogenesis of Alzheimer’s disease (AD) has remained elusive, it is known to increasethe expression of the antagonist of canonical wnt signalling, Dickkopf-1 (Dkk1), whereas the silencing ofDkk1blocks Abneur... Read More about Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.

Leukotriene B4 receptor locus gene characterisation and association studies in asthma (2012)
Journal Article
Tulah, A. S., Beghé, B., Barton, S. J., Holloway, J. W., & Sayers, I. (2012). Leukotriene B4 receptor locus gene characterisation and association studies in asthma. BMC Medical Genetics, 13(Novemb), Article 11. https://doi.org/10.1186/1471-2350-13-110

Background: Polymorphisms spanning genes involved in the production of leukotriene B4 (LTB4) e.g. ALOX5AP and
LTA4H are associated with asthma susceptibility, suggesting a role for LTB4 in disease. The contribution of LTB4
receptor polymorphism is... Read More about Leukotriene B4 receptor locus gene characterisation and association studies in asthma.