All Outputs (475)

Should treatment for Parkinson's disease start immediately on diagnosis or delayed until functional disability develops? (2011)
Journal Article

Background: Evidence from clinical trials with monoamine oxidase type B inhibitors (TEMPO, ADAGIO and DATATOP) and levodopa (ELLDOPA) suggests that Parkinson's disease patients may benefit from treatment being commenced immediately on diagnosis ra... Read More about Should treatment for Parkinson's disease start immediately on diagnosis or delayed until functional disability develops?.

The prevalence of metabolic syndrome in Latin America: A systematic review (2011)
Journal Article

Alien introgression in the grasses Lolium perenne (perennial ryegrass) and Festuca pratensis (meadow fescue): The development of seven monosomic substitution lines and their molecular and cytological characterization (2011)
Journal Article

BACKGROUND AND AIMS: To address the issues associated with food security, environmental change and bioenergy in the context of crop plants, the production, identification and evaluation of novel plant phenotypes is fundamental. One of the major rout... Read More about Alien introgression in the grasses Lolium perenne (perennial ryegrass) and Festuca pratensis (meadow fescue): The development of seven monosomic substitution lines and their molecular and cytological characterization.

Measurements of the ultraviolet background at 4.6 < z < 6.4 using the quasar proximity effect (2011)
Journal Article

We present measurements of the ionizing ultraviolet background (UVB) at z∼ 5–6 using the quasar proximity effect. The 15 quasars in our sample cover the range 4.6 < zq < 6.4, enabling the first proximity-effect measurements of the UVB at z > 5. The m... Read More about Measurements of the ultraviolet background at 4.6 < z < 6.4 using the quasar proximity effect.

All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study (2011)
Journal Article

Background: Mortality due to cirrhosis has tripled over the last 30 years in the UK. However, we lack adequate, contemporary, population-based estimates of the excess mortality patients who are at risk compared with the general population. Aim: To d... Read More about All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study.

Near-zone sizes and the rest-frame extreme ultraviolet spectral index of the highest redshift quasars (2011)
Journal Article

Implementation of case management in long-term conditions in England: Survey and case studies (2011)
Journal Article

Objectives: Our aim was to describe the current provision of case management arrangements in primary care for people with long-term conditions in England and identify the extent and nature of self-care support services within it. Methods: Cross-secti... Read More about Implementation of case management in long-term conditions in England: Survey and case studies.

Crohn disease: A current perspective on genetics, autophagy and immunity (2011)
Journal Article

Crohn disease (CD) is a chronic and debilitating inflammatory condition of the gastrointestinal tract.1 Prevalence in western populations is 100-150/100,000 and somewhat higher in Ashkenazi Jews. Peak incidence is in early adult life, although any ag... Read More about Crohn disease: A current perspective on genetics, autophagy and immunity.

Quantum Field Theory on Curved Noncommutative Spacetimes (2011)
Journal Article

We summarize our recently proposed approach to quantum field theory on noncommutative curved spacetimes. We make use of the Drinfel'd twist deformed differential geometry of Julius Wess and his group in order to define an action functional for a real... Read More about Quantum Field Theory on Curved Noncommutative Spacetimes.

Hurricanes and child health: lessons from Cuba (2011)
Journal Article

Adding more fuel to the fire: an eye-tracking study of idiom processing by native and non-native speaker (2011)
Journal Article

Using eye-tracking, we investigate on-line processing of idioms in a biasing story context by native and non-native speakers of English. The stimuli are idioms used figuratively (at the end of the day – ‘eventually’), literally (at the end of the day... Read More about Adding more fuel to the fire: an eye-tracking study of idiom processing by native and non-native speaker.

Bridging the gap: pracademics in foreign policy (2011)
Journal Article

In his seminal work Bridging the Gap: Theory and Practice in Foreign Policy, Alexander George (1993) lamented the great divide between academia and the foreign policymaking community, arguing that greater interaction between scholars and policymakers... Read More about Bridging the gap: pracademics in foreign policy.

Poo gurus? Researching the threats and opportunities presented by human waste (2011)
Journal Article

There is huge geographical variation in the extent to which excrement represents a threat to human and environmental health. In the UK, we tend to think little of such risks. By contrast, 52% of all people in Asia have no access to basic sanitation a... Read More about Poo gurus? Researching the threats and opportunities presented by human waste.

A heuristic algorithm for nurse scheduling with balanced preference satisfaction (2011)
Conference Proceeding

This paper tackles the nurse scheduling problem with balanced preference satisfaction which consists of generating an assignment of shifts to nurses over a given time horizon and ensuring that the satisfaction of nurses personal preferences for shift... Read More about A heuristic algorithm for nurse scheduling with balanced preference satisfaction.

Evolution of ?-blockers: from anti-anginal drugs to ligand-directed signalling (2011)
Journal Article

Sir James Black developed ?-blockers, one of the most useful groups of drugs in use today. Not only are they being used for their original purpose to treat angina and cardiac arrhythmias, but they are also effective therapeutics for hypertension, car... Read More about Evolution of ?-blockers: from anti-anginal drugs to ligand-directed signalling.

Evaluation of patient reporting of adverse drug reactions to the UK ‘Yellow Card Scheme’: literature review, descriptive and qualitative analyses, and questionnaire surveys (2011)
Book

Background: The monitoring of adverse drug reactions (ADRs) through pharmacovigilance is vital to patient safety. Spontaneous reporting of ADRs is one method of pharmacovigilance, and in the UK this is undertaken through the Yellow Card Scheme (YC... Read More about Evaluation of patient reporting of adverse drug reactions to the UK ‘Yellow Card Scheme’: literature review, descriptive and qualitative analyses, and questionnaire surveys.

Supporting nurse health champions: developing a 'new generation' of health improvement facilitators (2011)
Journal Article

In efforts to respond to key government public health initiatives for settings-based health promotion, the ‘Workplace Health Champion’ role has emerged as a method of promoting health within the UK healthcare setting. Health promotion techniques used... Read More about Supporting nurse health champions: developing a 'new generation' of health improvement facilitators.

Setting the stage – Building and working in an ancient DNA laboratory (2011)
Journal Article

With the introduction of next generation high throughput sequencing in 2005 and the resulting revolution in genetics, ancient DNA research has rapidly developed from an interesting but marginal field within evolutionary biology into one that can cont... Read More about Setting the stage – Building and working in an ancient DNA laboratory.

Making riverscapes real (2011)
Journal Article

Compensatory Neural Reorganization in Tourette Syndrome (2011)
Journal Article

Children with neurological disorders may follow unique developmental trajectories whereby they undergo compensatory neuroplastic changes in brain structure and function that help them gain control over their symptoms [1, 2, 3, 4, 5, 6]. We used behav... Read More about Compensatory Neural Reorganization in Tourette Syndrome.