All Outputs (180)

Spatial fluctuations in the spectral shape of the UV background at 2 (2006)
Journal Article

The low density hydrogen and helium in the IGM probed by QSO absorption lines is sensitive to the amplitude and spectral shape of the metagalactic UV background. We use realistic HI and HeII Ly-alpha forest spectra, constructed from state-of-the-art... Read More about Spatial fluctuations in the spectral shape of the UV background at 2.

Effects of fatty acids on skeletal muscle cell differentiation in vitro (2006)
Journal Article

Previous studies have shown stimulatory effects of linoleic acid (LA, C18:2) on differentiation of rat muscle cells in culture (Allen et al. 1985), but there appears to be little investigation of the effects of other fatty acids. The present study th... Read More about Effects of fatty acids on skeletal muscle cell differentiation in vitro.

Wireless mobile ad-hoc sensor networks for very large scale cattle monitoring (2006)
Conference Proceeding

This paper investigates the use of wireless mobile ad hoc sensor networks in the nationwide cattle monitoring systems. This problem is essential for monitoring general animal health and detecting outbreaks of animal diseases that can... Read More about Wireless mobile ad-hoc sensor networks for very large scale cattle monitoring.

Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain (2006)
Journal Article

Homeodomain proteins regulate multiple developmental pathways by altering gene expression temporally and in a tissue-specific fashion. The Proline Rich Homeodomain protein (PRH/Hex) is a transcription factor and an essential regulator of embryonic de... Read More about Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain.

Multifactorial day hospital intervention to reduce falls in high risk older people in primary care: a multi-centre randomised controlled trial [ISRCTN46584556] (2006)
Journal Article

Falls in older people are a major public health concern in terms of morbidity, mortality and cost. Previous studies suggest that multifactorial interventions can reduce falls, and many geriatric day hospitals are now offering falls intervention progr... Read More about Multifactorial day hospital intervention to reduce falls in high risk older people in primary care: a multi-centre randomised controlled trial [ISRCTN46584556].

Serotonin Increases Susceptibility to Pulmonary Hypertension in BMPR2 -Deficient Mice (2006)
Journal Article

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33 (2006)
Journal Article

The mouse monoclonal antibody (MAb) AP33, recognizing a 12 amino acid linear epitope in the hepatitis C virus (HCV) E2 glycoprotein, potently neutralizes retroviral pseudoparticles (HCVpp) carrying genetically diverse HCV envelope glycoproteins. Cons... Read More about Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

Purification and characterisation of the PRH homeodomain: removal of the N-terminal domain of PRH increases the PRH homeodomain-DNA interaction (2006)
Journal Article

The Proline-Rich Homeodomain (PRH) protein is a regulator of transcription and translation and plays a key role in the control of cell proliferation and cell differentiation. PRH contains an N-terminal proline-rich domain that can repress transcripti... Read More about Purification and characterisation of the PRH homeodomain: removal of the N-terminal domain of PRH increases the PRH homeodomain-DNA interaction.

Diffusible VP22-E2 protein kills bystander cells and offers a route for cervical cancer gene therapy (2006)
Journal Article

Human papillomaviruses (HPVs) are a causative agent of cervical cancer and are implicated in several other types of malignant disease including cancer of the vulva, oral cancer, and skin cancer. In HPV-transformed cells, expression of the viral E6 an... Read More about Diffusible VP22-E2 protein kills bystander cells and offers a route for cervical cancer gene therapy.

Systematic review and evaluation of methods of assessing urinary incontinence (2006)
Journal Article

Effort-reward imbalance at work and the co-occurrence of lifestyle risk factors: cross-sectional survey in a sample of 36,127 public sector employees (2006)
Journal Article

Background In occupational life, a mismatch between high expenditure of effort and receiving few rewards may promote the co-occurrence of lifestyle risk factors, however, there is insufficient evidence to support or refute this hypothesis. The aim o... Read More about Effort-reward imbalance at work and the co-occurrence of lifestyle risk factors: cross-sectional survey in a sample of 36,127 public sector employees.

Calculating an exceptional machine (2006)
Book Chapter

A classification of tasks for the systematic study of immune response using functional genomics data (2006)
Journal Article

A full understanding of the immune system and its responses to infection by different pathogens is important for the development of anti-parasitic vaccines. A growing number of large-scale experimental techniques, such as microarrays, are being used... Read More about A classification of tasks for the systematic study of immune response using functional genomics data.

A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans (2006)
Journal Article

We have previously reported that low-intensity microwave exposure (0.75-1.0 GHz CW at 0.5 W; SAR 4-40 mW kg-1) can induce an apparently non-thermal heat-shock response in Caenorhabditis elegans worms carrying hsp16-1::reporter genes. Using matched co... Read More about A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans.

Multiple-retrieval case-based reasoning for course timetabling problems (2006)
Journal Article

The structured representation of cases by attribute graphs in a Case-Based Reasoning (CBR) system for course timetabling has been the subject of previous research by the authors. In that system, the case base is organised as a decision tree and the r... Read More about Multiple-retrieval case-based reasoning for course timetabling problems.

Seismic retrofit schemes for RC structures and local-global consequences (2006)
Journal Article

A review of repair schemes for reinforced concrete frame buildings is presented in this paper, within the context of global objectives of the intervention process. Local as well as global intervention measures are discussed and their technological ap... Read More about Seismic retrofit schemes for RC structures and local-global consequences.

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension (2006)
Journal Article

Mutations of the TGF-? type II receptor BMPR2 in pulmonary arterial hypertension (2006)
Journal Article

Pulmonary arterial hypertension (PAH) is clinically characterized by a sustained elevation in mean pulmonary artery pressure leading to significant morbidity and mortality. The disorder is typically sporadic, and in such cases the term idiopathic PAH... Read More about Mutations of the TGF-? type II receptor BMPR2 in pulmonary arterial hypertension.

Genetic mapping of a major gene affecting onion bulb fructan content (2006)
Journal Article

The non-structural dry matter content of onion bulbs consists principally of fructose, glucose, sucrose and fructans. The objective of this study was to understand the genetic basis for the wide variation observed in the relative amounts of these car... Read More about Genetic mapping of a major gene affecting onion bulb fructan content.

Reconstructing the Origins and Dispersal of the Polynesian Bottle Gourd (Lagenaria siceraria) (2006)
Journal Article

The origin of the Polynesian bottle gourd (Lagenaria siceraria), an important crop species in prehistoric Polynesia, has remained elusive. Most recently, a South American origin has been favored as the bottle gourd could have been introduced from thi... Read More about Reconstructing the Origins and Dispersal of the Polynesian Bottle Gourd (Lagenaria siceraria).