All Outputs (214)

PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression (2021)
Working Paper

This protocol describes a cohort study comparing the risks of mortality and serious self-harm (suicide or near-fatal deliberate self-harm) between adults with depression prescribed mirtazapine, a selective serotonin reuptake inhibitor (SSRI), amitrip... Read More about PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression.

Do online support groups help individuals affected by HIV/AIDS?: A systematic review of the quantitative and qualitative literature (2021)
Working Paper

Background: Online support groups provide opportunities for individuals affected by HIV/AIDS to seek information, advice and support from peers. However, if and how engagement with online support groups helps individuals affected by HIV/AIDS remains... Read More about Do online support groups help individuals affected by HIV/AIDS?: A systematic review of the quantitative and qualitative literature.

Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study (2021)
Working Paper

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups conduc... Read More about Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study.

A systematic review and meta-analysis of Anakinra, Sarilumab, Siltuximab and Tocilizumab for Covid-19 (2021)
Working Paper

Background There is accumulating evidence for an overly activated immune response in severe Covid-19, with several studies exploring the therapeutic role of immunomodulation. Through systematic review and meta-analysis, we assess the effectiveness of... Read More about A systematic review and meta-analysis of Anakinra, Sarilumab, Siltuximab and Tocilizumab for Covid-19.

Zinc lability and solubility in soils of Ethiopia – an isotopic dilution study (2021)
Working Paper

Understanding each other's models: a standard representation of global water models to support improvement, intercomparison, and communication (2021)
Working Paper

Global water models (GWMs) simulate the terrestrial water cycle, on the global scale, and are used to assess the impacts of climate change on freshwater systems. GWMs are developed within different modeling frameworks and consider different underlyin... Read More about Understanding each other's models: a standard representation of global water models to support improvement, intercomparison, and communication.

The Functional Threshold: Direct International Legal Regulation of Collective Nonstate Entities and the Law of International Peace and Security (2020)
Working Paper

This article explores transformations in international law with respect to collective nonstate entities, challenging the mainstream view that international law stipulates rights and obligations directly binding on such entities only on an exceptional... Read More about The Functional Threshold: Direct International Legal Regulation of Collective Nonstate Entities and the Law of International Peace and Security.

Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort (2020)
Working Paper

Objective: This study examined the COVID-19 risk perceptions and mental health of university students on returning to campus in the midst of the COVID-19 pandemic. Methods: An online survey was completed during the first four weeks of the academic... Read More about Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort.

The influence of surface charge on the coalescence of ice and dust particles in the mesosphere (2020)
Working Paper

Agglomeration of charged ice and dust particles in the mesosphere is studied using a classical electrostatic approach, which is extended to capture the induced polarisation of surface charge. Collision outcomes are predicted whilst varying particle s... Read More about The influence of surface charge on the coalescence of ice and dust particles in the mesosphere.

Mobilising molluscan models and genomes in biology (2020)
Working Paper

Molluscs are amongst the most ancient, diverse, and important of all animal taxa. Even so, no individual mollusc species has emerged as a broadly applied model system in biology. We here make the case that both perceptual and methodological barriers... Read More about Mobilising molluscan models and genomes in biology.

Comparing short and long batteries to assess deficits and their neural bases in stroke aphasia (2020)
Working Paper

Multiple language assessments are necessary for diagnosing, characterising and quantifying the multifaceted deficits observed in many patients’ post-stroke. Current language batteries, however, tend to be an imperfect trade-off between time and sensi... Read More about Comparing short and long batteries to assess deficits and their neural bases in stroke aphasia.

The rhetoric of closed borders: quotas, lax enforcement and illegal immigration (2020)
Working Paper

Governments do not always enforce their laws, even when they have the means of doing so, and lax enforcement is common in the domain of immigration policy. To explain this paradox we develop a political agency model where gains from migration are une... Read More about The rhetoric of closed borders: quotas, lax enforcement and illegal immigration.

COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees During the COVID-19 Pandemic (2020)
Working Paper

Skill-Biased Structural Change (2020)
Working Paper

Using a broad panel of advanced economies we document that increases in GDP per capita are associated with a systematic shift in the composition of value added to sectors that are intensive in high-skill labor, a process we label as skill-biased stru... Read More about Skill-Biased Structural Change.

Morbidity and complications of diabetes mellitus in children and adolescents in Ghana: study design and rationale (2020)
Working Paper

Background: Diabetes is associated with premature morbidity and mortality from its many complications. There is limited data on the chronic complications of diabetes in children and adolescents in sub-Saharan Africa. Objective: The study aims t... Read More about Morbidity and complications of diabetes mellitus in children and adolescents in Ghana: study design and rationale.

Full species-wide leaf and seed ionomic diversity of Arabidopsis thaliana (2020)
Working Paper

• Soil is a heterogenous reservoir of essential elements needed for plant growth and development. Plants have evolved mechanisms to balance their nutritional needs based on availability of nutrients. This has led to genetically-based variation in the... Read More about Full species-wide leaf and seed ionomic diversity of Arabidopsis thaliana.

Immediate impact of transcranial magnetic stimulation on brain structure: short-term neuroplasticity following one session of cTBS (2020)
Working Paper

Recent evidence demonstrates that activation-dependent neuroplasticity on a structural level can occur in a short time (2 hour or less) in humans. However, the exact time scale of structural plasticity in adult human brain remains unclear. Using voxe... Read More about Immediate impact of transcranial magnetic stimulation on brain structure: short-term neuroplasticity following one session of cTBS.

Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study) (2020)
Working Paper

Background: Effective help for depression and anxiety only reaches a small proportion of those who might benefit from it. The scale of the problem suggests a role for effective, safe public health online services delivered directly to the public. On... Read More about Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study).

Evidence for selection in a prokaryote pangenome (2020)
Working Paper

A pangenome is the complete set of genes (core and accessory) present in a phylogenetic clade. We hypothesize that a pangenome’s accessory gene content is structured and maintained by selection. To test this hypothesis, we interrogated the genomes of... Read More about Evidence for selection in a prokaryote pangenome.

Altered hippocampal functional connectivity patterns in patients with cognitive impairments following ischaemic stroke: a resting-state fMRI study (2020)
Working Paper

Background Ischemic stroke with cognitive impairment is a considerable risk factor for developing dementia. Identifying imaging markers of cognitive impairment following ischemic stroke will help to develop prevention strategies against post-stroke d... Read More about Altered hippocampal functional connectivity patterns in patients with cognitive impairments following ischaemic stroke: a resting-state fMRI study.