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Controlled semantic cognition relies upon dynamic and flexible interactions between the executive ‘semantic control’ and hub-and-spoke ‘semantic representation’ systems (2018)
Journal Article
Chiou, R., Humphreys, G. F., Jung, J., & Lambon Ralph, M. A. (2018). Controlled semantic cognition relies upon dynamic and flexible interactions between the executive ‘semantic control’ and hub-and-spoke ‘semantic representation’ systems. Cortex, 103, 100-116. https://doi.org/10.1016/j.cortex.2018.02.018

© 2018 The Author(s) Built upon a wealth of neuroimaging, neurostimulation, and neuropsychology data, a recent proposal set forth a framework termed controlled semantic cognition (CSC) to account for how the brain underpins the ability to flexibly us... Read More about Controlled semantic cognition relies upon dynamic and flexible interactions between the executive ‘semantic control’ and hub-and-spoke ‘semantic representation’ systems.

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database (2018)
Journal Article
Coupland, C., Hill, T., Morriss, R., Moore, M., Arthur, A., & Hippisley-Cox, J. (2018). Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database. BMC Medicine, 16(1), Article 36. https://doi.org/10.1186/s12916-018-1022-x

© 2018 The Author(s). Background: Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age group. Th... Read More about Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database.

Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol) (2018)
Journal Article
Doleman, B., Leonardi-Bee, J., Heinink, T. P., Lund, J., & Williams, J. P. (2018). Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol). Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012978

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate in adult participants undergoing all types of surgery, the effects of pre-emptive and preventive non-steroidal anti-inflammatory drugs (NSAIDs) com... Read More about Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol).

Hip precautions after hip operation (HippityHop): protocol for a before and after study evaluating hip precautions following total hip replacement (2018)
Journal Article
Lightfoot, C., Sehat, K., Drury, G., Brewin, C., Coole, C., & Drummond, A. E. (in press). Hip precautions after hip operation (HippityHop): protocol for a before and after study evaluating hip precautions following total hip replacement. British Journal of Occupational Therapy, https://doi.org/10.1177/0308022618757183

Introduction Hip precautions are routinely used despite inconclusive evidence that they reduce dislocations, and concern that they impede activities of daily living. HippityHop compares a change in practice locally from implementing routine hip prec... Read More about Hip precautions after hip operation (HippityHop): protocol for a before and after study evaluating hip precautions following total hip replacement.

Synchronisation in the prefrontal-striatal circuit tracks behavioural choice in a go no-go task in rats (2018)
Journal Article
Stubbendorff, C., Molano-Mazon, M., Young, A. M., & Gerdjikov, T. V. (in press). Synchronisation in the prefrontal-striatal circuit tracks behavioural choice in a go no-go task in rats. European Journal of Neuroscience, https://doi.org/10.1111/ejn.13905

Rodent striatum is involved in sensory-motor transformations and reward-related learning. Lesion studies suggest dorsolateral striatum, dorsomedial striatum, and nucleus accumbens underlie stimulus-response transformations, goal-directed behaviour an... Read More about Synchronisation in the prefrontal-striatal circuit tracks behavioural choice in a go no-go task in rats.

Noise evaluation of a point autofocus surface topography measuring instrument (2018)
Journal Article
Maculotti, G., Feng, X., Galetto, M., & Leach, R. K. (2018). Noise evaluation of a point autofocus surface topography measuring instrument. Measurement Science and Technology, 29(6), https://doi.org/10.1088/1361-6501/aab528

In this work, the measurement noise of a point autofocus surface topography measuring instrument is evaluated, as the first step towards establishing a route to traceability for this type of instrument. The evaluation is based on the determination of... Read More about Noise evaluation of a point autofocus surface topography measuring instrument.

Fibre sub-type specific conduction reveals metabolic function in mouse sciatic nerve (2018)
Journal Article
Rich, L., & Brown, A. M. (2018). Fibre sub-type specific conduction reveals metabolic function in mouse sciatic nerve. Journal of Physiology, 596(10), https://doi.org/10.1113/JP275680

The stimulus evoked compound action potential (CAP), recorded using suction electrodes, provides an index of the relative number of conducting axons within a nerve trunk. As such the CAP has been used to elucidate the diverse mechanisms of injury res... Read More about Fibre sub-type specific conduction reveals metabolic function in mouse sciatic nerve.

Central Bank interest rate decisions, household indebtedness, and psychiatric morbidity and distress: evidence from the UK (2018)
Journal Article
Boyce, C. J., Delaney, L., Ferguson, E., & Wood, A. M. (2018). Central Bank interest rate decisions, household indebtedness, and psychiatric morbidity and distress: evidence from the UK. Journal of Affective Disorders, 234, https://doi.org/10.1016/j.jad.2018.03.003

Background: Central banks set economy-wide interest rates to meet exclusively economic objectives. There is a strong link between indebtedness and psychiatric morbidity at the individual level, with interest rates being an important factor determinin... Read More about Central Bank interest rate decisions, household indebtedness, and psychiatric morbidity and distress: evidence from the UK.

Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment (2018)
Journal Article
Brookes, M. J., Groom, M. J., Liuzzi, L., Hill, R. M., Smith, H. J., Briley, P. M., …Liddle, E. B. (2018). Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment. NeuroImage, 174, https://doi.org/10.1016/j.neuroimage.2018.03.008

Network connectivity is an integral feature of human brain function, and characterising its maturational trajectory is a critical step towards understanding healthy and atypical neurodevelopment. Here, we used magnetoencephalography (MEG) to investig... Read More about Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment.

The challenges posed by equine arboviruses (2018)
Journal Article
Chapman, G. E., Baylis, M., Archer, D., & Daly, J. M. (2018). The challenges posed by equine arboviruses. Equine Veterinary Journal, 50(4), 436-445. https://doi.org/10.1111/evj.12829

Equine populations worldwide are at increasing risk of infection by viruses transmitted by biting arthropods including mosquitoes, biting midges (Culicoides), sandflies and ticks. These include the flaviviruses (Japanese encephalitis, West Nile and M... Read More about The challenges posed by equine arboviruses.

Water-in-oil-in-water double emulsion for the delivery of starter cultures in reduced-salt moromi fermentation of soy sauce (2018)
Journal Article
Devanthi, P. V. P., Linforth, R., El Kadri, H., & Gkatzionis, K. (2018). Water-in-oil-in-water double emulsion for the delivery of starter cultures in reduced-salt moromi fermentation of soy sauce. Food Chemistry, 257, https://doi.org/10.1016/j.foodchem.2018.03.022

This study investigated the application of water-oil-water (W1/O/W2) double emulsions (DE) for yeast encapsulation and sequential inoculation of Zygosaccharomyces rouxii and Tetragenococcus halophilus in moromi stage of soy sauce fermentation with re... Read More about Water-in-oil-in-water double emulsion for the delivery of starter cultures in reduced-salt moromi fermentation of soy sauce.

Prediction of enteric methane production, yield and intensity in dairy cattle using an intercontinental database (2018)
Journal Article
Niu, M., Kebreab, E., Hristov, A. N., Oh, J., Arndt, C., Bannink, A., …Yu, Z. (2018). Prediction of enteric methane production, yield and intensity in dairy cattle using an intercontinental database. Global Change Biology, 24(8), https://doi.org/10.1111/gcb.14094

Enteric methane (CH₄) production from cattle contributes to global greenhouse gas emissions. Measurement of enteric CH₄ is complex, expensive and impractical at large scales; therefore, models are commonly used to predict CH₄ production. However, bui... Read More about Prediction of enteric methane production, yield and intensity in dairy cattle using an intercontinental database.

A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: the NOTEPAD study Protocol (2018)
Journal Article
Burroughs, H., Bartlam, B., Kingstone, T., Shepherd, T., Ogollah, R. O., Proctor, J., …Chew-Graham, C. (2018). A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: the NOTEPAD study Protocol. Trials, 19, Article 172. https://doi.org/10.1186/s13063-018-2550-6

BACKGROUND: Anxiety and depression are common among older people, with up to 20% reporting such symptoms, and the prevalence increases with co-morbid chronic physical health problems. Access to treatment for anxiety and depression in this population... Read More about A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: the NOTEPAD study Protocol.

Laser drilling of microholes in single crystal silicon using continuous wave (CW) 1070 nm fiber lasers with millisecond pulse widths (2018)
Journal Article
Maclean, J. O., Hodson, J., Tangkijcharoenchai, C., Al-Ojaili, S., Rodsavas, S., Coomber, S., & Voisey, K. (2018). Laser drilling of microholes in single crystal silicon using continuous wave (CW) 1070 nm fiber lasers with millisecond pulse widths. Lasers in Engineering, 39(1-2),

The laser microdrilling of via holes in Si semiconductor wafers was studied using 1 ms pulses from an Yb fibre laser with 1070 nm wavelength. Optical microscopy and cross‑sectional analysis were used to quantify hole dimensions, the distribution of r... Read More about Laser drilling of microholes in single crystal silicon using continuous wave (CW) 1070 nm fiber lasers with millisecond pulse widths.

An investigation into whether the laser drilling capabilities of a 2kW fibre laser can be enhanced using pulse train shaping (2018)
Journal Article
Markcoons, D., & Voisey, K. (2018). An investigation into whether the laser drilling capabilities of a 2kW fibre laser can be enhanced using pulse train shaping. Lasers in Engineering, 39(1-2),

In long, ms, pulsed melt ejected based laser drilling of metals pulse train shaping has previously improved drilling efficiency. This work investigates if pulse train shaping can be exploited in the laser drilling of 0.8-2 mm mild steel with a 1070 n... Read More about An investigation into whether the laser drilling capabilities of a 2kW fibre laser can be enhanced using pulse train shaping.

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort (2018)
Journal Article
Mukherjee, A., Russell, R., Chin, S., Liu, B., Rueda, O., Ali, H., …Provenzano, E. (2018). Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort. npj Breast Cancer, 4(1), Article 5. https://doi.org/10.1038/s41523-018-0056-8

The integration of genomic and transcriptomic profiles of 2000 breast tumours from the METABRIC [Molecular Taxonomy of Breast Cancer International Consortium] cohort revealed ten subtypes, termed integrative clusters (IntClust/s), characterised by di... Read More about Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

Synthesis and thermoelectric properties of 2- and 2,8-substituted tetrathiotetracenes (2018)
Journal Article
Robert Garrett, M., Durán-Peña, M. J., Lewis, W., Pudzs, K., Uzulis, J., Mihailovs, I., …Woodward, S. (2018). Synthesis and thermoelectric properties of 2- and 2,8-substituted tetrathiotetracenes. Journal of Materials Chemistry C, 6(13), 3403-3409. https://doi.org/10.1039/c8tc00073e

Reaction of elemental sulfur with 2-R1 and 2,8-R1,R2-substituted tetracenes (2) in refluxing DMF affords 5,6,11,12 tetrathiotetracenes (1) in good yields (74-99%) for a range of substituents where R1,R2 are: H,H (a); Me,H (b); MeO,H (c); Ph,H (d); Me... Read More about Synthesis and thermoelectric properties of 2- and 2,8-substituted tetrathiotetracenes.

Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes (2018)
Journal Article
Almulathanon, A. A., Ranucci, E., Ferruti, P., Garnett, M. C., & Bosquillon, C. (2018). Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes. Pharmaceutical Research, 35(4), Article 86. https://doi.org/10.1007/s11095-017-2328-7

Purpose: This study aimed to further explore the mechanisms behind the ability of certain linear polyamidoamines (PAAs) to transfect cells with minimal cytotoxicity. Methods: The transfection efficiency of DNA complexed with a PAA of a molecular we... Read More about Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes.

Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands (2018)
Journal Article
Alea-Reyes, M. E., Penon, O., García Calavia, P., Marín, M. J., Russell, D. A., & Pérez-García, L. (2018). Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands. Journal of Colloid and Interface Science, 521, https://doi.org/10.1016/j.jcis.2018.03.014

Hypothesis Metalloporphyrins are extensively investigated for their ability to form reactive oxygen species and as potent photosensitisers for use in photodynamic therapy. However, their hydrophobicity generally causes solubility issues concerning... Read More about Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands.

Electrochemical Sensor for Bilirubin Detection Using Screen Printed Electrodes Functionalized with Carbon Nanotubes and Graphene (2018)
Journal Article
Thangamuthu, M., Gabriel, W., Santschi, C., & Martin, O. (2018). Electrochemical Sensor for Bilirubin Detection Using Screen Printed Electrodes Functionalized with Carbon Nanotubes and Graphene. Sensors, 18(3), Article 800. https://doi.org/10.3390/s18030800

Practice oriented point-of-care diagnostics require easy-to-handle, miniaturized, and low-cost analytical tools. In a novel approach, screen printed carbon electrodes (SPEs), which were functionalized with nanomaterials, are employed for selective me... Read More about Electrochemical Sensor for Bilirubin Detection Using Screen Printed Electrodes Functionalized with Carbon Nanotubes and Graphene.