All Outputs (37679)

Adaptive regulation or governmentality: patient safety and the changing regulation of medicine
Journal Article

Studies from across the world have shown that clinical mistakes are a major threat to the safety of patient care (World Health Organisation 2004). For the National Health Service (NHS) of England and Wales it is estimated that one in ten hospital pat... Read More about Adaptive regulation or governmentality: patient safety and the changing regulation of medicine.

Beyond Blame: cultural barriers to medical reporting
Journal Article

The paper explores the attitudes of medical physicians towards adverse incident reporting in health care, with particular focus on the inhibiting factors or barriers to participation. It is recognised that there are major barriers to medical reporti... Read More about Beyond Blame: cultural barriers to medical reporting.

Inclusion, Participation and the Emergence of British Chinese Websites
Journal Article

Previous work has drawn attention to the relative absence of British Chinese voices in public culture. No one is more aware of this invisibility than British-born Chinese people themselves. Since 2000 the emergence of Internet discussion sites prod... Read More about Inclusion, Participation and the Emergence of British Chinese Websites.

Fractured families--united countries?: family, nostalgia and nationbuilding in Das Wunder von Bern and Goodbye Lenin!
Journal Article

The article compares the role and construction of nostalgia in two of the most successful German films released in 2003, Das Wunder von Bern and Goodbye Lenin!. While both films portray a close connection between male adolescence, incomplete families... Read More about Fractured families--united countries?: family, nostalgia and nationbuilding in Das Wunder von Bern and Goodbye Lenin!.

"Ordinary people only": knowledge, representativeness and the publics of public participation in healthcare
Journal Article

Public involvement in healthcare is a prominent policy in countries across the economically developed world. A growing body of academic literature has focused on public participation, often presenting dichotomies between good and bad practice: betwe... Read More about "Ordinary people only": knowledge, representativeness and the publics of public participation in healthcare.

Recombinant expression of Aryl Hydrocarbon Receptor for quantitative ligand-binding analysis
Journal Article

Recombinant expression of the Aryl Hydrocarbon Receptor (AhR) yields small amounts of ligand- binding competent AhR. Therefore, Spodoptera frugiperda (Sf9) cells and baculovirus have been evaluated for high level and functional expression of AhR. R... Read More about Recombinant expression of Aryl Hydrocarbon Receptor for quantitative ligand-binding analysis.

Landscape-mindscape: writing in Scotland’s prehistoric future
Journal Article

Density-dependent fitness benefits in quorum-sensing bacterial populations
Journal Article

It has been argued that bacteria communicate using small diffusible signal molecules to coordinate, among other things, the production of factors that are secreted outside of the cells in a process known as quorum sensing (QS). The underlying assumpt... Read More about Density-dependent fitness benefits in quorum-sensing bacterial populations.

The effective mathematics department: adding value and increasing participation?
Journal Article

Given the commonly accepted view that having a mathematically well-educated populace is strategically important, there is considerable international interest in raising attainment, and increasing participation, in post-compulsory mathematics educatio... Read More about The effective mathematics department: adding value and increasing participation?.

Lipidomic analysis of serum from horses with strongyle infection
Journal Article

The development of techniques capable of accurate diagnosis of strongyle infections is at the forefront of research in equine parasitology. The aim of this study was to evaluate the potential, for using lipidomics in the diagnosis of strongyle infect... Read More about Lipidomic analysis of serum from horses with strongyle infection.

18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells
Journal Article

Background: One requisite of quantitative reverse transcription PCR (qRT-PCR) is to normalise the data with an internal reference gene that is invariant regardless of treatment, such as virus infection. Several studies have found variability in the... Read More about 18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells.

Structural optimization of molecular clusters with density functional theory combined with basin hopping
Journal Article

Identifying the energy minima of molecular clusters is a challenging problem. Traditionally, search algorithms such as simulated annealing, genetic algorithms, or basin hopping are usually used in conjunction with empirical force fields. We have impl... Read More about Structural optimization of molecular clusters with density functional theory combined with basin hopping.

Regulation of cel genes of C. cellulolyticum: identification of GlyR2, a transcriptional regulator regulating cel5D gene expression
Journal Article

Transcription and expression regulation of some individual cel genes (cel5A, cel5I, cel5D and cel44O) of Clostridium cellulolyticum were investigated. Unlike the cip-cel operon, these genes are transcribed as monocistronic units of transcription, exc... Read More about Regulation of cel genes of C. cellulolyticum: identification of GlyR2, a transcriptional regulator regulating cel5D gene expression.

Making Science Public as a route to better evidence
Journal Article

It is widely accepted that scientific evidence should play a role in policy decisions, yet the form that this should or could take remains subject to intense debate. Warren Pearce and Sujatha Raman discuss how the Making Science Public project attemp... Read More about Making Science Public as a route to better evidence.

Two-component signal transduction system CBO0787/ CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502
Journal Article

Blocking neurotransmission, botulinum neurotoxin is the most poisonous biological substance known to mankind. Despite its infamy as the scourge of the food industry, the neurotoxin is increasingly used as a pharmaceutical to treat an expanding range... Read More about Two-component signal transduction system CBO0787/ CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502.

Exploring haemodynamics of haemodialysis using extrema points analysis model
Journal Article

Background: Haemodialysis is a form of renal replacement therapy used to treat patients with end stage renal failure. It is becoming more appreciated that haemodialysis patients exhibit higher rates of multiple end organ damage compared to the gen... Read More about Exploring haemodynamics of haemodialysis using extrema points analysis model.

Delivery and use of individualised feedback in large class medical teaching
Journal Article

Background: Formative feedback that encourages self-directed learning in large class medical teaching is difficult to deliver. This study describes a new method, blueprinted feedback, and explores learner’s responses to assess its appropriate use w... Read More about Delivery and use of individualised feedback in large class medical teaching.

Time for curriculum reform: the case of mathematics
Journal Article

Mathematics education is rarely out of the policy spotlight in England. Over the last ten years, considerable attention has been given to improving 14-19 mathematics curriculum pathways. In this paper we consider some of the challenges of enacting cu... Read More about Time for curriculum reform: the case of mathematics.

Measuring proton shift tensors with ultrafast MAS NMR
Journal Article

A new proton anisotropic-isotropic shift correlation experiment is described which operates with ultrafast MAS, resulting in good resolution of isotropic proton shifts in the detection dimension. The new experiment makes use of a recoupling sequence... Read More about Measuring proton shift tensors with ultrafast MAS NMR.

A generic ?* shape resonance observed in energy-dependent photoelectron angular distributions from two-colour, resonant multiphoton ionization of difluorobenzene isomers
Journal Article

We present new evidence for the existence of a near threshold ?* shape resonance as a common feature in the photoionization of each isomer of difluorobenzene. Experimentally this is revealed by significant changes in the anisotropy of the photoelectr... Read More about A generic ?* shape resonance observed in energy-dependent photoelectron angular distributions from two-colour, resonant multiphoton ionization of difluorobenzene isomers.