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Lipidomic analysis of serum from horses with strongyle infection

Lamb, Jenna; Hallowell, Gayle D.; Harris, Patricia; Xing-Quan, Zhu; Elsheikha, Hany M.

Authors

Jenna Lamb

Gayle D. Hallowell

Patricia Harris

Zhu Xing-Quan

Hany M. Elsheikha

Abstract

The development of techniques capable of accurate diagnosis of strongyle infections is at the forefront of research in equine parasitology. The aim of this study was to evaluate the potential, for using lipidomics in the diagnosis of strongyle infection. Blood and fecal samples were collected from 30 horses. Fecal egg count (FEC) results were used to select the serum samples from six uninfected horses (negative controls) and from the five horses with the highest burdens. The lipid portion of serum samples was extracted and analyzed using High Performance Liquid Chromatography-Mass Spectroscopy. The concentrations of 66 lipid metabolites differed between infected and uninfected horses (p

Journal Article Type Article
Journal Journal of Veterinary Science and Technology
Electronic ISSN 2157-7579
Publisher OMICS International
Peer Reviewed Peer Reviewed
Volume 3
Issue 6
Article Number 122
Institution Citation Lamb, J., Hallowell, G. D., Harris, P., Xing-Quan, Z., & Elsheikha, H. M. Lipidomic analysis of serum from horses with strongyle infection. Journal of Veterinary Science and Technology, 3(6), doi:10.4172/2157-7579.1000122
DOI https://doi.org/10.4172/2157-7579.1000122
Publisher URL http://omicsonline.org/2157-7579/2157-7579-3-122.digital/2157-7579-3-122.html
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0




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