All Outputs (4)

The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response (2019)
Journal Article
Till, C. J., Vicente, J., Zhang, H., Oszvald, M., Deery, M. J., Pastor, V., …Holdsworth, M. J. (2019). The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response. Plant Direct, 3(12), Article e00194. https://doi.org/10.1002/pld3.194

N-degron pathways of ubiquitin-mediated proteolysis (formerly known as the N-end rule pathway) control the stability of substrate proteins dependent on the amino-terminal (Nt) residue. Unlike yeast or mammalian N-recognin E3 ligases, which each recog... Read More about The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.

The plant N?degron pathways of ubiquitin?mediated proteolysis (2019)
Journal Article
Holdsworth, M. J., Vicente, J., Sharma, G., Abbas, M., & Zubrycka, A. (2020). The plant N?degron pathways of ubiquitin?mediated proteolysis. Journal of Integrative Plant Biology, 62(1), 70-89. https://doi.org/10.1111/jipb.12882

The amino?terminal residue of a protein (or amino?terminus of a peptide following protease cleavage) can be an important determinant of its stability, through the Ubiquitin?Proteasome?System associated N?degron pathways. Plants contain a unique combi... Read More about The plant N?degron pathways of ubiquitin?mediated proteolysis.

Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress (2019)
Journal Article
Hartman, S., Liu, Z., Van Veen, H., Vicente, J., Reinen, E., Martopawiro, S., …Voesenek, L. A. (2019). Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress. Nature Communications, 10, Article 4020. https://doi.org/10.1038/s41467-019-12045-4

Timely perception of adverse environmental changes is critical for survival. Dynamic changes in gases are important cues for plants to sense environmental perturbations, such as submergence. In Arabidopsis thaliana, changes in oxygen and nitric oxide... Read More about Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress.

The Scope, Functions, and Dynamics of Posttranslational Protein Modifications (2019)
Journal Article
Millar, A. H., Heazlewood, J. L., Giglione, C., Holdsworth, M. J., Bachmair, A., & Schulze, W. X. (2019). The Scope, Functions, and Dynamics of Posttranslational Protein Modifications. Annual Review of Plant Biology, 70, 119-151. https://doi.org/10.1146/annurev-arplant-050718-100211

© 2019 by Annual Reviews. All rights reserved. Assessing posttranslational modification (PTM) patterns within protein molecules and reading their functional implications present grand challenges for plant biology. We combine four perspectives on PTMs... Read More about The Scope, Functions, and Dynamics of Posttranslational Protein Modifications.