All Outputs (3811)
Large neighbourhood search with adaptive guided ejection search for the pickup and delivery problem with time windows (2018)
Journal Article
© 2018, The Author(s). An effective and fast hybrid metaheuristic is proposed for solving the pickup and delivery problem with time windows. The proposed approach combines local search, large neighbourhood search and guided ejection search in a novel... Read More about Large neighbourhood search with adaptive guided ejection search for the pickup and delivery problem with time windows.
Growing up in a megalopolis: environmental effects on galaxy evolution in a supercluster at z?0.65 in UKIDSS UDS (2018)
Journal Article
We present a large-scale galaxy structure Cl J021734-0513 at z ∼ 0.65 discovered in the UKIDSS UDS field, made of ∼ 20 galaxy groups and clusters, spreading over 10 Mpc. We report on a VLT/VIMOS spectroscopic follow-up program that, combined with pas... Read More about Growing up in a megalopolis: environmental effects on galaxy evolution in a supercluster at z?0.65 in UKIDSS UDS.
Stable DHLA–PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging (2018)
Journal Article
The short shelf-life of water-soluble quantum dots (QDs) due to colloidal instability represents a major drawback to their exploitation. This work examines the colloidal stability of PbS nanoparticles capped with dihydrolipoic acid–polyethylene glyco... Read More about Stable DHLA–PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging.
Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans (2018)
Journal Article
The molecular and metabolic mechanisms underlying the increase in insulin sensitivity (i.e. increased insulin-stimulated skeletal muscle glucose uptake, phosphorylation and storage as glycogen) observed from 12 to 48 h following a single bout of exer... Read More about Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans.
Quantitative outcomes of a One Health approach to study global health challenges (2018)
Journal Article
Having gained momentum in the last decade, the One Health initiative promotes a holistic approach to address complex global health issues. Before recommending its adoption to stakeholders, however, it is paramount to first compile quantitative eviden... Read More about Quantitative outcomes of a One Health approach to study global health challenges.
Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence (2018)
Journal Article
Large repeat rich genomes present challenges for assembly using short read technologies. The 32 Gb axolotl genome is estimated to contain ~19 Gb of repetitive DNA making an assembly from short reads alone effectively impossible. Indeed, this model sp... Read More about Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence.
Views and experiences of seeking information and help for vitiligo: a qualitative study of written accounts (2018)
Journal Article
Objectives: Vitiligo is a relatively common autoimmune condition causing loss of skin pigment. Around 1 in 100 people in the UK develop vitiligo. It can have a significant impact on quality of life for many of those affected. How people access inform... Read More about Views and experiences of seeking information and help for vitiligo: a qualitative study of written accounts.
Microstructure and properties of C/C–ZrC composites prepared by hydrothermal deposition combined with carbothermal reduction (2018)
Journal Article
Carbon fiber reinforced carbon matrix containing ZrC (C/C–ZrC) composites were prepared by hydrothermal deposition combined with carbothermal reduction. The submicron ZrC particles (100~300 nm) were dispersed in the matrix. The stress-strain curves o... Read More about Microstructure and properties of C/C–ZrC composites prepared by hydrothermal deposition combined with carbothermal reduction.
Emotional intelligence and caring in health care professionals (2018)
Journal Article
Background: Over recent years there has been criticism within the United Kingdom’s health service regarding a lack of care and compassion, resulting in adverse outcomes for patients. The impact of emotional intelligence in staff on patient health car... Read More about Emotional intelligence and caring in health care professionals.
High nuclear MSK1 is associated with longer survival in breast cancer patients (2018)
Journal Article
Purpose: Mitogen- and stress- activated kinases (MSKs) are important substrates of the mitogen-activated protein kinase (MAPK)-activated protein kinase family. MSK1 and MSK2 are both nuclear serine/threonine protein kinases, with MSK1 being suggested... Read More about High nuclear MSK1 is associated with longer survival in breast cancer patients.
Epidemiological survey of equine influenza in Andalusia, Spain (2018)
Journal Article
Equine influenza is a highly contagious respiratory disease considered the most important respiratory disease in equids. Although influenza A virus (IAV) has caused outbreaks in equids worldwide, surveillance on these species in Spain has not been co... Read More about Epidemiological survey of equine influenza in Andalusia, Spain.
Selective CO2 hydrogenation to formic acid with multifunctional ionic liquids (2018)
Journal Article
The development of simple, cost-effective and sustainable methods to transform CO2 into feedstock chemicals is essential to reduce the dependence on fossil fuels of the chemical industry. Here, we report the selective and efficient catalytic hydrogen... Read More about Selective CO2 hydrogenation to formic acid with multifunctional ionic liquids.
Incidence and prevalence of patellofemoral pain: a systematic review and meta-analysis (2018)
Journal Article
Background: Patellofemoral pain is considered one of the most common forms of knee pain, affecting adults, adolescents, and physically active populations. Inconsistencies in reported incidence and prevalence exist and in relation to the allocation of... Read More about Incidence and prevalence of patellofemoral pain: a systematic review and meta-analysis.
Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria (2018)
Journal Article
Mitochondrial Ca2+ homoeostasis regulates aerobic metabolism and cell survival. Ca2+ flux into mitochondria is mediated by the mitochondrial calcium uniporter (MCU) channel whereas Ca2+ export is often through an electrogenic Na+–Ca2+ exchanger. Here... Read More about Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria.
Analysis of intercomponent energy transfer in the interaction of oscillating-grid turbulence with an impermeable boundary (2018)
Journal Article
New experimental results are presented that investigate the nature of the intercomponent energy transfer that occurs in the interaction between oscillating-grid turbulence and a solid impermeable boundary, using instantaneous velocity measurements ob... Read More about Analysis of intercomponent energy transfer in the interaction of oscillating-grid turbulence with an impermeable boundary.
Shape-related characteristics of age-related differences in subcortical structures (2018)
Journal Article
OBJECTIVES: With an increasing aging population, it is important to gain a better understanding of biological markers of aging. Subcortical volume is known to differ with age; additionally considering shape-related characteristics may provide a bette... Read More about Shape-related characteristics of age-related differences in subcortical structures.
Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery (2018)
Journal Article
A robust discovery methodology is presented to identify novel biomaterials suitable for 3D printing. Currently the application of Additive Manufacturing is limited by the availability of functional inks, especially in the area of biomaterials-this me... Read More about Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery.
A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort (2018)
Journal Article
Objectives: Cognitive deficits are a common feature of neuropsychiatric disorders. We investigated the relationship between cognitive performance and a deletion allele within GluK4 protective against risk for bipolar disorder, in 1642 individuals fro... Read More about A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort.
Candidate high-z proto-clusters among the Planck compact sources, as revealed by Herschel-SPIRE (2018)
Journal Article
By determining the nature of all the Planck compact sources within 808.4 deg2 of large Herschel surveys, we have identified 27 candidate proto-clusters of dusty star forming galaxies (DSFGs) that are at least 3σ overdense in either 250, 350 or 500 μm... Read More about Candidate high-z proto-clusters among the Planck compact sources, as revealed by Herschel-SPIRE.