All Outputs (3811)

Owners and veterinary surgeons in the United Kingdom disagree about what should happen during a small animal vaccination consultation (2018)
Journal Article

Dog and cat vaccination consultations are a common part of small animal practice in the United Kingdom. Few data are available describing what happens during those consultations or what participants think about their content. The aim of this novel st... Read More about Owners and veterinary surgeons in the United Kingdom disagree about what should happen during a small animal vaccination consultation.

Dynamic interplay between photodamage and photoprotection in photosystem II (2018)
Journal Article

Toward Investigation of External Oil Flow From a Journal Bearing in an Epicyclic Gearbox (2018)
Journal Article

High loads and bearing life requirements make journal bearings the preferred choice for use in high power, planetary gearboxes in jet engines. With the planet gears rotating about their own axis and orbiting around the sun gear, centrifugal forces ge... Read More about Toward Investigation of External Oil Flow From a Journal Bearing in an Epicyclic Gearbox.

Avoiding the internet of insecure industrial things (2018)
Journal Article

Security incidents such as targeted distributed denial of service (DDoS) attacks on power grids and hacking of factory industrial control systems (ICS) are on the increase. This paper unpacks where emerging security risks lie for the industrial inter... Read More about Avoiding the internet of insecure industrial things.

Motivic equivalence of affine quadrics (2018)
Journal Article

In this article we show that the motive of an affine quadric {q=1} determines the respective quadratic form.

Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway (2018)
Journal Article

Nineteen analogues of cardamonin were semi-synthesized and tested against A549 and HK1 cell lines. The analogues were fully characterized via IR and NMR analyses, while compound 19 (a Cu (II) complex of cardamonin) was further characterized via HRMS,... Read More about Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway.

3D extrusion printing of high drug loading immediate release paracetamol tablets (2018)
Journal Article

The manufacture of immediate release high drug loading paracetamol oral tablets was achieved using an extrusion based 3D printer from a premixed water based paste formulation. The 3D printed tablets demonstrate that a very high drug (paracetamol) loa... Read More about 3D extrusion printing of high drug loading immediate release paracetamol tablets.

Rate after-effects fail to transfer cross-modally: evidence for distributed sensory timing mechanisms (2018)
Journal Article

Accurate time perception is critical for a number of human behaviours, such as understanding speech and the appreciation of music. However, it remains unresolved whether sensory time perception is mediated by a central timing component regulating all... Read More about Rate after-effects fail to transfer cross-modally: evidence for distributed sensory timing mechanisms.

Psychosocial interventions for people with dementia: a synthesis of systematic reviews (2018)
Journal Article

© 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Objectives: Over the last 10years there has been a multitude of studies of psychosocial interventions for people with dementia. However, clinical serv... Read More about Psychosocial interventions for people with dementia: a synthesis of systematic reviews.

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018)
Journal Article

Vitamin D is a steroid hormone precursor that is associated with a range of human traits and diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). I... Read More about Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Species distribution modelling: contrasting presence-only models with plot abundance data (2018)
Journal Article

Species distribution models (SDMs) are widely used in ecology and conservation. Presence-only SDMs such as MaxEnt frequently use natural history collections (NHCs) as occurrence data, given their huge numbers and accessibility. NHCs are often spatial... Read More about Species distribution modelling: contrasting presence-only models with plot abundance data.

Development and validation of self-reported line drawings of the modified Beighton score for the assessment of generalised joint hypermobility (2018)
Journal Article

Background: The impracticalities and comparative expense of carrying out a clinical assessment is an obstacle in many large epidemiological studies. The purpose of this study was to develop and validate a series of electronic self-reported line drawi... Read More about Development and validation of self-reported line drawings of the modified Beighton score for the assessment of generalised joint hypermobility.

The impact of de-tiering in the UK's large value payment system (2018)
Journal Article

Large-value payment systems (LVPS) often have a tiered structure where only a limited number of banks have direct access to these systems and every other institution accesses the system through agency arrangements with the direct participants. As suc... Read More about The impact of de-tiering in the UK's large value payment system.

The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors (2018)
Journal Article

The dopamine D2 and D3 receptors (D2R and D3R) are important targets for antipsychotics and for the treatment of drug abuse. SB269652, a bitopic ligand that simultaneously binds both the orthosteric binding site (OBS) and a secondary binding pocket (... Read More about The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors.

Identifying rail asset maintenance processes: a human-centric and sensemaking approach (2018)
Journal Article

Efficient asset maintenance is key for delivering services such as transport. Current rail maintenance processes have been mostly reactive with a recent shift towards exploring proactive modes. The introduction of new ubiquitous technologies and adva... Read More about Identifying rail asset maintenance processes: a human-centric and sensemaking approach.

Progress towards a methodology for high throughput 3D reconstruction of soot nanoparticles via electron tomography (2018)
Journal Article

The aim of this work is to make progress towards the development of 3D reconstruction as a legitimate alternative to traditional 2D characterisation of soot. Time constraints are the greatest opposition to its implementation, as currently reconstruct... Read More about Progress towards a methodology for high throughput 3D reconstruction of soot nanoparticles via electron tomography.

An iterated local search algorithm for the team orienteering problem with variable profits (2018)
Journal Article

The orienteering problem (OP) is a routing problem that has numerous applications in various domains such as logistics and tourism. The objective is to determine a subset of vertices to visit for a vehicle so that the total collected score is maximiz... Read More about An iterated local search algorithm for the team orienteering problem with variable profits.

Voltage- and light-controlled spin properties of a two-dimensional hole gas in p-type GaAs/AlAs resonant tunneling diodes (2018)
Journal Article

We have investigated the spin properties of a two-dimensional hole gas (2DHG) formed at the contact layer of a p-type GaAs/AlAs resonant tunneling diode (RTD). We have measured the polarized-resolved photoluminescence of the RTD as a function of bias... Read More about Voltage- and light-controlled spin properties of a two-dimensional hole gas in p-type GaAs/AlAs resonant tunneling diodes.

Adaptive wild bootstrap tests for a unit root with non-stationary volatility (2018)
Journal Article

© 2017 The Authors. The Econometrics Journal published by John Wiley & Sons Ltd on behalf of Royal Economic Society. Recent research has emphasized that permanent changes in the innovation variance (caused by structural shifts or an integrated vola... Read More about Adaptive wild bootstrap tests for a unit root with non-stationary volatility.

Variation and constraints in hybrid genome formation (2018)
Journal Article

Hybridization is an important source of variation; it transfers adaptive genetic variation across species boundaries and generates new species. Yet, the limits to viable hybrid genome formation are poorly understood. Here we investigated to what exte... Read More about Variation and constraints in hybrid genome formation.