All Outputs (3714)

Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers (2017)
Journal Article

The objective of this study was to assess both independent and combined effects of routine foot trimming of heifers at 3 weeks pre-calving and 100 days post calving on the first lactation lameness and lactation productivity. A total of 419 pre-calvin... Read More about Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers.

Combined inkjet printing and infrared sintering of silver nanoparticles using a swathe-by-swathe and layer-by-layer approach for 3-dimensional structures (2017)
Journal Article

Despite the advancement of additive manufacturing (AM)/3-dimensional (3D) printing, single-step fabrication of multifunctional parts using AM is limited. With the view of enabling multifunctional AM (MFAM), in this study, sintering of metal nanoparti... Read More about Combined inkjet printing and infrared sintering of silver nanoparticles using a swathe-by-swathe and layer-by-layer approach for 3-dimensional structures.

Patient safety incidents involving sick children in primary care in England and Wales: a mixed methods analysis (2017)
Journal Article

Background: The UK performs poorly relative to other economically developed countries on numerous indicators of care quality for children. The contribution of iatrogenic harm to these outcomes is unclear. As primary care is the first point of health... Read More about Patient safety incidents involving sick children in primary care in England and Wales: a mixed methods analysis.

Lessons learned from the London Exercise and Pregnant (LEAP) Smokers randomised controlled trial process evaluation: implications for the design of physical activity for smoking cessation interventions during pregnancy (2017)
Journal Article

Background: The challenges of delivering interventions for pregnant smokers have been poorly documented. Also, the process of promoting a physical activity intervention for pregnant smokers has not been previously recorded. This study describes the e... Read More about Lessons learned from the London Exercise and Pregnant (LEAP) Smokers randomised controlled trial process evaluation: implications for the design of physical activity for smoking cessation interventions during pregnancy.

Colour-kinematics duality and the Drinfeld double of the Lie algebra of diffeomorphisms (2017)
Journal Article

Colour-kinematics duality suggests that Yang-Mills (YM) theory possesses some hidden Lie algebraic structure. So far this structure has resisted understanding, apart from some progress in the self-dual sector. We show that there is indeed a Lie algeb... Read More about Colour-kinematics duality and the Drinfeld double of the Lie algebra of diffeomorphisms.

Development of Clostridium difficile R20291?PaLoc model strains and in vitro methodologies reveals CdtR is required for the production of CDT to cytotoxic levels (2017)
Journal Article

Assessing the regulation of Clostridium difficile transferase (CDT), is complicated by the presence of a Pathogenicity locus (PaLoc) which encodes Toxins A and B. Here we developed R20291?PaLoc model strains and cell-based assays to quantify CDT-medi... Read More about Development of Clostridium difficile R20291?PaLoc model strains and in vitro methodologies reveals CdtR is required for the production of CDT to cytotoxic levels.

Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot ‘Prevention of decline in cognition after stroke trial’ (PODCAST) randomised controlled trial (2017)
Journal Article

Background Stroke is associated with the development of cognitive impairment and dementia. We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive outcomes in patients with recent stroke in a pilot trial. Meth... Read More about Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot ‘Prevention of decline in cognition after stroke trial’ (PODCAST) randomised controlled trial.

Heterogeneous network epidemics: real-time growth, variance and extinction of infection (2017)
Journal Article

© 2017, The Author(s). Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model... Read More about Heterogeneous network epidemics: real-time growth, variance and extinction of infection.

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with acidic stores (lysosomes) in the heart (2017)
Journal Article

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) stimulates calcium release from acidic stores such as lysosomes and is a highly potent calcium-mobilising second messenger. NAADP plays an important role in calcium signalling in the heart under b... Read More about High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with acidic stores (lysosomes) in the heart.

Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer (2017)
Journal Article

Inflammatory breast cancer (IBC) is a virulent form of breast cancer, and novel treatment strategies are urgently needed. Immunohistochemical analysis of tumors from women with a clinical diagnosis of IBC (n = 147) and those with non-IBC breast cance... Read More about Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer.

Scene-selective coding by single neurons in the human parahippocampal cortex (2017)
Journal Article

Imaging, electrophysiological, and lesion studies have shown a relationship between the parahippocampal cortex (PHC) and the processing of spatial scenes. Our present knowledge of PHC, however, is restricted to the macroscopic properties and dynamics... Read More about Scene-selective coding by single neurons in the human parahippocampal cortex.

Multipath extraction and mitigation for bridge deformation monitoring using a single-difference model (2017)
Journal Article

Multipath is one of the primary error sources in high precision GNSS applications. Since it is highly correlated with observation environments , the multipath effect is difficult to be parameterized with an empirical model or eliminated by current di... Read More about Multipath extraction and mitigation for bridge deformation monitoring using a single-difference model.

Randomized clinical trial of preoperative oral versus intravenous iron in anaemic patients with colorectal cancer (2017)
Journal Article

Combining plasmonic trap filling and optical backscattering for highly efficient third generation solar cells (2017)
Journal Article

© The Royal Society of Chemistry. Metal oxide contact layers such as ZnO and TiOx are commonly used in third generation solar cells as they can be solution processed and have a relatively high conductivity. It is well known that by ultraviolet (UV) l... Read More about Combining plasmonic trap filling and optical backscattering for highly efficient third generation solar cells.

Geometry control of closed contour forming in uniform micro metal droplet deposition manufacturing (2017)
Journal Article

Micro metal droplet deposition manufacturing shows great potential applications in many industrial areas such as micro circuits printing, thin-wall metal parts, porous metal parts, and heterogeneous material parts. However, excessive overlapping of m... Read More about Geometry control of closed contour forming in uniform micro metal droplet deposition manufacturing.

Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin-induced myotoxicity (2017)
Journal Article

The association of lipophilic statins with plasma lipoproteins in the presence of disturbed acid-base balance can modify the pharmacokinetics and tissue distribution of these drugs, resulting in alteration in their efficacy and toxicity profiles. The... Read More about Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin-induced myotoxicity.

Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions (2017)
Journal Article

We summarize here the results presented and subsequent discussion from the meeting on Integrating Hebbian and Homeostatic Plasticity at the Royal Society in April 2016. We first outline the major themes and results presented at the meeting. We next p... Read More about Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.

Probing the diamagnetic term in light–matter interaction (2017)
Journal Article

We address the quantum estimation of the diamagnetic, or A 2, term in an effective model of light–matter interaction featuring two coupled oscillators. First, we calculate the quantum Fisher information of the diamagnetic parameter in the interacting... Read More about Probing the diamagnetic term in light–matter interaction.

Technologies to support community-dwelling persons with dementia: a position paper on issues regarding development, usability, effectiveness and cost-effectiveness, deployment, and ethics (2017)
Journal Article

Background: With the expected increase in the numbers of persons with dementia, providing timely, adequate, and affordable care and support is challenging. Assistive and health technologies may be a valuable contribution in dementia care, but new cha... Read More about Technologies to support community-dwelling persons with dementia: a position paper on issues regarding development, usability, effectiveness and cost-effectiveness, deployment, and ethics.

Surface modification of PdlLGA microspheres with gelatine methacrylate: evaluation of adsorption, entrapment, and oxygen plasma treatment approaches (2017)
Journal Article

Injectable poly (dl-lactic-co-glycolic acid) (PdlLGA) microspheres are promising candidates as biodegradable controlled release carriers for drug and cell delivery applications; however, they have limited functional groups on the surface to enable de... Read More about Surface modification of PdlLGA microspheres with gelatine methacrylate: evaluation of adsorption, entrapment, and oxygen plasma treatment approaches.