All Outputs (3714)

Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery (2017)
Journal Article

A spirocyclic, sp3-atom rich oxetane-containing scaffold was synthesised in just two steps via a gold catalysed propargylic alcohol rearrangement. The key gold cyclisation can be undertaken on a 40 g scale allowing the preparation of 419 lead-like co... Read More about Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery.

The 13th data release of the Sloan Digital Sky Survey: first spectroscopic data from the SDSS-IV survey mapping nearby galaxies at Apache Point Observatory (2017)
Journal Article

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) began observations in 2014 July. It pursues three core programs: the Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2), Mapping Nearby Galaxies at APO (MaNGA), and the... Read More about The 13th data release of the Sloan Digital Sky Survey: first spectroscopic data from the SDSS-IV survey mapping nearby galaxies at Apache Point Observatory.

Controllable synthesis of (NH4)Fe2(PO4)2(OH)·2H2O using two-step route: Ultrasonic-intensified impinging stream pre-treatment followed by hydrothermal treatment (2017)
Journal Article

© 2017 Elsevier B.V. (NH4)Fe2(PO4)2(OH)·2H2O samples with different morphology are successfully synthesized via two-step synthesis route – ultrasonic-intensified impinging stream pre-treatment followed by hydrothermal treatment (UIHT) method. The eff... Read More about Controllable synthesis of (NH4)Fe2(PO4)2(OH)·2H2O using two-step route: Ultrasonic-intensified impinging stream pre-treatment followed by hydrothermal treatment.

Community based response to the Japanese tsunami: A bottom-up approach (2017)
Journal Article

The 2011 Tohuku earthquake and tsunami are said to be the most powerful ever to hit Japan. The result was tremendous loss of life, homes and livelihoods; the destruction of infrastructures; and the disruption of basic facilities. The aftermath of thi... Read More about Community based response to the Japanese tsunami: A bottom-up approach.

Unified viscoplasticity modelling and its application to fatigue-creep behaviour of gas turbine rotor (2017)
Journal Article

This paper presents an elasto-visco-plastic finite element modelling framework including the associated UMAT codes to investigate the high temperature behaviour of gas turbine rotor steels. The model used in the FE study is an improved and unified mu... Read More about Unified viscoplasticity modelling and its application to fatigue-creep behaviour of gas turbine rotor.

Patient characteristics and outcome measurement in a low secure forensic hospital (2017)
Journal Article

Background: Health services are increasingly required to measure outcomes after treatment, which can be reported to the funding body and may be scrutinised by the public. Extensive high quality measurements are time consuming. Routinely collected cli... Read More about Patient characteristics and outcome measurement in a low secure forensic hospital.

Chinese refugee children and empires: the politics of international adoptions in cold war Hong Kong (2017)
Journal Article

With the support of new sources from British and Hong Kong archives, this study casts new light on the post-war international adoptions of Chinese refugee children in the British colony of Hong Kong. It argues that while children were ‘saved’ and fou... Read More about Chinese refugee children and empires: the politics of international adoptions in cold war Hong Kong.

Synthetic light-curable polymeric materials provide a supportive niche for dental pulp stem cells (2017)
Journal Article

Dental disease annually affects billions of patients, and while regenerative dentistry aims to heal dental tissue after injury, existing polymeric restorative materials, or fillings, do not directly participate in the healing process in a bioinstruct... Read More about Synthetic light-curable polymeric materials provide a supportive niche for dental pulp stem cells.

Fluorinated electrolytes for li-ion batteries: the lithium difluoro(oxalato)borate additive for stabilizing the solid electrolyte interphase (2017)
Journal Article

Fluorinated electrolytes based on fluoroethylene carbonate (FEC) have been considered as promising alternative electrolytes for high-voltage and high-energy capacity lithium-ion batteries (LIBs). However, the compatibility of the fluorinated electrol... Read More about Fluorinated electrolytes for li-ion batteries: the lithium difluoro(oxalato)borate additive for stabilizing the solid electrolyte interphase.

Scientific synergy between LSST and Euclid (2017)
Journal Article

Euclid and the Large Synoptic Survey Telescope (LSST) are poised to dramatically change the astronomy landscape early in the next decade. The combination of high-cadence, deep, wide-field optical photometry from LSST with high-resolution, wide-field... Read More about Scientific synergy between LSST and Euclid.

Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016 (2017)
Journal Article

Following notification of a Salmonella enterica serovar Typhimurium gastroenteritis outbreak, we identified 82 cases linked to a restaurant with symptom onset from 12 February 2015 to 8 March 2016. Seventy-two cases had an isolate matching the nation... Read More about Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016.

A research team’s perspective on the editorial 'Revolutionary reform in psychiatric care in Italy: The abolition of forensic mental hospitals' (2017)
Journal Article

Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines (2017)
Journal Article

© 2017 The Author(s). Mineral content of complete pet food is regulated to ensure health of the companion animal population. Analysis of adherence to these regulatory guidelines has not been conducted. Here, mineral composition of complete wet (n = 9... Read More about Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines.

Alcohol Misuse and Injury Outcomes in Young People Aged 10–24 (2017)
Journal Article

Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health out... Read More about Alcohol Misuse and Injury Outcomes in Young People Aged 10–24.

An exploration of solutions for improving access to affordable fresh food with disadvantaged Welsh communities (2017)
Journal Article

Our research is rooted in community operational research (community OR) and adopts a qualitative problem structuring approach to exploring potential solutions for addressing inequality in access to affordable healthy food in disadvantaged communities... Read More about An exploration of solutions for improving access to affordable fresh food with disadvantaged Welsh communities.

Generalised path-following for well-behaved nonlinear structures (2017)
Journal Article

Recent years have seen a research revival in structural stability analysis. This renewed interest stems from a paradigm shift regarding the role of buckling instabilities in engineering design—from detrimental sources of catastrophic failure to novel... Read More about Generalised path-following for well-behaved nonlinear structures.

Physical and rheological characterization of carbonated bitumen for paving applications (2017)
Journal Article

In the paving industry, current attempts aimed at reducing greenhouse gas emissions have focused on the development of technologies that decrease bitumen viscosity so that asphalt mixtures can be produced at temperatures that are lower than conventio... Read More about Physical and rheological characterization of carbonated bitumen for paving applications.

An automated method to detect and quantify fungiform papillae in the human tongue: Validation and relationship to phenotypical differences in taste perception (2017)
Journal Article

Determination of the number of fungiform papillae (FP) on the human tongue is an important measure that has frequently been associated with individual differences in oral perception, including taste sensitivity. At present, there is no standardised m... Read More about An automated method to detect and quantify fungiform papillae in the human tongue: Validation and relationship to phenotypical differences in taste perception.

The scope and limits of accounting and judicial courts intervention in inefficient public procurement (2017)
Journal Article

Cost inefficiencies in public procurement tend to come from two sources: corruption (moral hazard) and incompetence (adverse selection). In most countries, audit authorities are responsible for monitoring costs but do not distinguish both sources of... Read More about The scope and limits of accounting and judicial courts intervention in inefficient public procurement.

Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography (2017)
Journal Article

Background: Rising cirrhosis incidence and mortality in the United Kingdom has been attributed predominantly to excess alcohol consumption. However, metabolic risk factors such as type 2 diabetes and obesity may also be important. Aim: To screen at-... Read More about Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography.