All Outputs (194)

Differentiation-dependent changes in the membrane properties of fiber cells isolated from the rat lens (2008)
Journal Article

Impedance measurements in whole lenses showed that lens fiber cells possess different permeability properties to the epithelial cells from which they differentiate. To confirm these observations at the cellular level, we analyzed the membrane propert... Read More about Differentiation-dependent changes in the membrane properties of fiber cells isolated from the rat lens.

Calculation of sample size for stroke trials assessing functional outcome: comparison of binary and ordinal approaches (2008)
Journal Article

Background Many acute stroke trials have given neutral results. Sub-optimal statistical analyses may be failing to detect efficacy. Methods which take account of the ordinal nature of functional outcome data are more efficient. We compare sample... Read More about Calculation of sample size for stroke trials assessing functional outcome: comparison of binary and ordinal approaches.

Reconstructing hydrological variability in Lake Baikal during MIS 11: An application of oxygen isotope analysis of diatom silica (2008)
Journal Article

In this paper we reconstruct hydrological variability in Lake Baikal during Marine Isotope Stage 11 (MIS 11) (427-362 ka BP) from oxygen isotope analysis of diatom silica. Highest δ18Odiatom values are found during MIS 11.3, highlighting the dominanc... Read More about Reconstructing hydrological variability in Lake Baikal during MIS 11: An application of oxygen isotope analysis of diatom silica.

‘Not rocket science’ or ‘No silver bullet’? Media and government discourses about MRSA and cleanliness (2008)
Journal Article

Methicillin-resistant Staphylococcus aureus (MRSA), commonly called a superbug, has recently been a major political issue in the UK, playing a significant role in debates over health policy in the general election held in 2005. While science recogniz... Read More about ‘Not rocket science’ or ‘No silver bullet’? Media and government discourses about MRSA and cleanliness.

Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis (2008)
Journal Article

Gating of sensory information can be assessed using an auditory conditioning-test paradigm which measures the reduction in the auditory evoked response to a test stimulus following an initial conditioning stimulus. Recording brainwaves from specific... Read More about Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis.

Role of VGF-derived peptides in the control of food intake, body weight and reproduction (2008)
Journal Article

VGF is a 68-kDa polypeptide synthesized in neuronal and neuroendocrine cells. It is cleaved into a number of smaller peptides which are stored in dense core vesicles and are likely to be secreted products. The VGF gene is expressed abundantly in the... Read More about Role of VGF-derived peptides in the control of food intake, body weight and reproduction.

In the kingdom of the blind: successfully implementing institutional repositories in the UK and the SHERPA Partnership experience (2008)
Journal Article

This paper takes an overview of the work of SHERPA team and the SHERPA Partnership institutions in the area of developing, populating and maintaining institutional open access repositories. Crucial to this work has been the development of mutually s... Read More about In the kingdom of the blind: successfully implementing institutional repositories in the UK and the SHERPA Partnership experience.

Possible evidence for an inverted temperature-density relation in the intergalactic medium from the flux distribution of the Lyman-alpha forest (2008)
Journal Article

Exercise intervention in acquired brain injury rehabilitation: a discussion (2008)
Journal Article

Physical activity is essential for health and well-being. The importance of an active lifestyle is increasingly being recognized in rehabilitation for its benefits to quality of life and the prevention and management of secondary disease resulting fr... Read More about Exercise intervention in acquired brain injury rehabilitation: a discussion.

The "home country" of a multinational enterprise group facing insolvency (2008)
Journal Article

Identifying the ‘home country’ for the multinational enterprise group’s insolvency proceedings can be crucial for allowing an effective insolvency process for related entities. However, this is a challenging task given the diversity of group structu... Read More about The "home country" of a multinational enterprise group facing insolvency.

Cow, farm, and herd management factors in the dry period associated with raised somatic cell counts in early lactation (2008)
Journal Article

This study investigated cow characteristics, farm facilities, and herd management strategies during the dry period to examine their joint influence on somatic cell counts (SCC) in early lactation. Data from 52 commercial dairy farms throughout Englan... Read More about Cow, farm, and herd management factors in the dry period associated with raised somatic cell counts in early lactation.

Innovation in practice: mobile phone technology in patient care (2008)
Journal Article

Mobile phones are becoming increasingly important in everyday life and now in healthcare. There has been a steady growth of information and communication technologies in health communication and technology is used progressively in telemedicine, wirel... Read More about Innovation in practice: mobile phone technology in patient care.

Structural and electrical characterization of AuPtAlTi ohmic contacts to AlGaN/GaN with varying annealing temperature and Al content (2008)
Journal Article

The effect of varying annealing temperature and Al layer thickness on the structural and electrical characteristics of AuPtAlTi/AlGaN/GaN ohmic contact structures has been systematically investigated. The relationship between annealing temperature, A... Read More about Structural and electrical characterization of AuPtAlTi ohmic contacts to AlGaN/GaN with varying annealing temperature and Al content.

G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors (2008)
Journal Article

The human dopamine D2L receptor couples promiscuously to multiple members of the Gαi/o subfamily. Despite the high homology of the D2L and D3 receptors, the G protein coupling specificity of the human D3 receptor is less clearly characterized. The pr... Read More about G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors.

Development of a Genomic Microsatellite Library in Perennial Ryegrass (Lolium perenne) and its Use in Trait Mapping (2008)
Journal Article

Background and Aims Perennial ryegrass (Lolium perenne) is one of the key forage and amenity grasses throughout the world. In the UK it accounts for 70 % of all agricultural land use with an estimated farm gate value of £6 billion per annum. However... Read More about Development of a Genomic Microsatellite Library in Perennial Ryegrass (Lolium perenne) and its Use in Trait Mapping.

Identifying genetic components controlling fertility in the outcrossing grass species perennial ryegrass (Lolium perenne) by quantitative trait loci analysis and comparative genetics (2008)
Journal Article

Mutational load and resource allocation factors and their effects on limiting seed set were investigated in ryegrass by comparative mapping genomics and quantitative trait loci (QTL) analysis in two perennial ryegrass (Lolium perenne) mapping familie... Read More about Identifying genetic components controlling fertility in the outcrossing grass species perennial ryegrass (Lolium perenne) by quantitative trait loci analysis and comparative genetics.

The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum (2008)
Journal Article

MUC1 is a high molecular weight glycoprotein that is overexpressed in breast cancer. Aberrant O-linked glycosylation of MUC1 in cancer has been implicated in disease progression. We investigated the O-linked glycosylation of MUC1 purified from the se... Read More about The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum.

Structure of the N-terminal oligomerization domain of DnaD reveals a unique tetramerization motif and provides insights into scaffold formation (2008)
Journal Article

DnaD is a primosomal protein that remodels supercoiled plasmids. It binds to supercoiled forms and converts them to open forms without nicking. During this remodeling process, all the writhe is converted to twist and the plasmids are held around the... Read More about Structure of the N-terminal oligomerization domain of DnaD reveals a unique tetramerization motif and provides insights into scaffold formation.

Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension (2008)
Journal Article

Formulaic sequences: Are they processed more quickly than nonformulaic language by native and nonnative speakers? (2008)
Journal Article

It is generally accepted that formulaic sequences like take the bull by the horns serve an important function in discourse and are widespread in language. It is also generally believed that these sequences are processed more efficiently because singl... Read More about Formulaic sequences: Are they processed more quickly than nonformulaic language by native and nonnative speakers?.