All Outputs (941)

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study (2021)
Journal Article
Hippisley-Cox, J., Coupland, C. A., Mehta, N., Keogh, R. H., Diaz-Ordaz, K., Khunti, K., …Nguyen-Van-Tam, J. S. (2021). Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study. BMJ, 374, Article n2244. https://doi.org/10.1136/bmj.n2244

Objectives To derive and validate risk prediction algorithms to estimate the risk of covid-19 related mortality and hospital admission in UK adults after one or two doses of covid-19 vaccination. Design Prospective, population based cohort study usin... Read More about Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study.

Case-finding and genetic testing for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Case-finding and genetic testing for familial hypercholesterolaemia in primary care. Heart, 107(24), 1956-1961. https://doi.org/10.1136/heartjnl-2021-319742

Objective: Familial Hypercholesterolaemia (FH) is a common inherited disorder causing premature heart disease and death. We have developed novel case-finding algorithms (FAMCAT version 1 & 2) for application in primary care, to improve detection of... Read More about Case-finding and genetic testing for familial hypercholesterolaemia in primary care.

Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19 (2021)
Journal Article
Au-Yong, I., Higashi, Y., Giannotti, E., Fogarty, A., Morling, J. R., Grainge, M., …Card, T. (2022). Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology, 302(2), 460-469. https://doi.org/10.1148/radiol.2021210986

Background Radiographic severity may help predict patient deterioration and outcomes from COVID-19 pneumonia. Purpose To assess the reliability and reproducibility of three chest radiograph reporting systems (radiographic assessment of lung edema [RA... Read More about Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19.

The global incidence of bullous pemphigoid: a systematic review and meta-analysis (2021)
Journal Article
Persson, M. S., Begum, N., Grainge, M. J., Harman, K. E., Grindlay, D., & Gran, S. (2022). The global incidence of bullous pemphigoid: a systematic review and meta-analysis. British Journal of Dermatology, 186(3), 414-425. https://doi.org/10.1111/bjd.20743

Background: Bullous pemphigoid (BP) is an autoimmune blistering disorder that mainly affects older people. Although the disease is associated with considerable morbidity and mortality, the burden of disease worldwide is unclear. Objectives: The study... Read More about The global incidence of bullous pemphigoid: a systematic review and meta-analysis.

Yoga Program for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People: Qualitative Study to Explore Reasons for Non-participation in a Feasibility Randomized Controlled Trial in India (2021)
Journal Article
Mishra, P., Greenfield, S., Harris, T., Hamer, M., Lewis, S. A., Singh, K., …Chattopadhyay, K. (2021). Yoga Program for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People: Qualitative Study to Explore Reasons for Non-participation in a Feasibility Randomized Controlled Trial in India. Frontiers in Public Health, 9, Article 682203. https://doi.org/10.3389/fpubh.2021.682203

Background: Yoga-based interventions can be effective in preventing type 2 diabetes mellitus (T2DM). We developed a Yoga program for T2DM prevention (YOGA-DP) among high-risk people and conducted a feasibility randomized controlled trial (RCT) in Ind... Read More about Yoga Program for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People: Qualitative Study to Explore Reasons for Non-participation in a Feasibility Randomized Controlled Trial in India.

Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity (2021)
Journal Article
Innes, H., Crooks, C. J., Aspinall, E., Card, T. R., Hamill, V., Dillon, J., …Morling, J. R. (2022). Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity. Hepatology, 75(2), 369-378. https://doi.org/10.1002/hep.32123

Background and Aims: It is thought that alcohol intake and body mass index (BMI) interact supra-additively to modulate the risk of cirrhosis, but evidence for this phenomenon is limited. We investigated the interrelationship between alcohol and BMI o... Read More about Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity.

Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy (2021)
Journal Article
Slaich, B., Claire, R., Emery, J., Lewis, S., Cooper, S., Thomson, R., …Coleman, T. (2022). Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy. Addiction, 117(3), 751-759. https://doi.org/10.1111/add.15671

Background and Aims Although English Stop Smoking Services routinely offer dual nicotine replacement therapy (NRT) to help pregnant women quit smoking, little is known about how nicotine and tobacco smoke exposures following this compares with that... Read More about Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy.

The Effect of Covid-19 on Alcohol Use Disorder and the Role of Universal Alcohol Screening in an Inpatient Setting: A Retrospective Cohort Control Study (2021)
Journal Article
Subhani, M., Sheth, A., Unitt, S., Aithal, G. P., Ryder, S. D., & Morling, J. R. (2022). The Effect of Covid-19 on Alcohol Use Disorder and the Role of Universal Alcohol Screening in an Inpatient Setting: A Retrospective Cohort Control Study. Alcohol and Alcoholism, 57(2), 203-210. https://doi.org/10.1093/alcalc/agab059

Aim: To assess the impact of Covid-19 on alcohol use disorders (AUD) and the role of universal alcohol screening (UAS) in an inpatient setting. Methods: Retrospective cohorts were defined as pre-pandemic and pandemic admitted to Nottingham University... Read More about The Effect of Covid-19 on Alcohol Use Disorder and the Role of Universal Alcohol Screening in an Inpatient Setting: A Retrospective Cohort Control Study.

Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes (2021)
Journal Article
Sand, L., Szatkowski, L., Kwok, T. C., Sharkey, D., Todd, D. A., Budge, H., & Ojha, S. (2022). Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107(2), 150-155. https://doi.org/10.1136/archdischild-2021-322390

Objective: To determine the change in non-invasive ventilation (NIV) use over time in infants born at

Association between characteristics of behavioural weight loss programmes and weight change after programme end: systematic review and meta-analysis (2021)
Journal Article
Hartmann-Boyce, J., Theodoulou, A., Oke, J. L., Butler, A. R., Scarborough, P., Bastounis, A., …Aveyard, P. (2021). Association between characteristics of behavioural weight loss programmes and weight change after programme end: systematic review and meta-analysis. BMJ, 374, Article n1840. https://doi.org/10.1136/bmj.n1840

Objective: To determine if the characteristics of behavioural weight loss programmes influence the rate of change in weight after the end of the programme. Design: Systematic review and meta-analysis. Data sources: Trial registries, 11 electron... Read More about Association between characteristics of behavioural weight loss programmes and weight change after programme end: systematic review and meta-analysis.

A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data (2021)
Journal Article
Bishton, M. J., Stilwell, P., Card, T. R., Lanyon, P., Ban, L., Elliss-Brookes, L., …Bythell, M. (2021). A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data. British Journal of Haematology, 194(6), 1039-1044. https://doi.org/10.1111/bjh.17768

We assessed the validity of coded healthcare data to identify cases of haemophagocytic lymphohistiocytosis (HLH). Hospital Episode Statistics (HES) identified 127 cases within five hospital Trusts 2013–2018 using ICD-10 codes D76.1, D76.2 and D76.3.... Read More about A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data.

Hospital-acquired SARS-CoV-2 infection in the UK's first COVID-19 pandemic wave (2021)
Journal Article
Read, J. M., Green, C. A., Harrison, E. M., Docherty, A. B., Funk, S., Harrison, J., …Semple, M. G. (2021). Hospital-acquired SARS-CoV-2 infection in the UK's first COVID-19 pandemic wave. Lancet, 398(10305), 1037-1038. https://doi.org/10.1016/S0140-6736%2821%2901786-4

Developing a novel e-cigarette regulatory and policy control scale: results from the European Union (2021)
Journal Article
Shah, A., Britton, J., & Bogdanovica, I. (2022). Developing a novel e-cigarette regulatory and policy control scale: results from the European Union. Drugs: Education, Prevention, and Policy, 29(6), 719-725. https://doi.org/10.1080/09687637.2021.1959520

Background: E-cigarette regulations vary considerably between countries though a standard approach for comparing regulatory frameworks does not exist. Additionally, there is no evidence on whether regulatory variations are associated with differences... Read More about Developing a novel e-cigarette regulatory and policy control scale: results from the European Union.

What is the Definition of Cure in Non-small Cell Lung Cancer? (2021)
Journal Article
Morgan, H., Ellis, L., O’Dowd, E. L., Murray, R. L., Hubbard, R., & Baldwin, D. R. (2021). What is the Definition of Cure in Non-small Cell Lung Cancer?. Oncology and Therapy, 9(2), 365-371. https://doi.org/10.1007/s40487-021-00163-3

The concept of cure from cancer is important to patients, but can be difficult to communicate in terms that are meaningful. This is because there are a number of definitions of cure that are applied by clinicians, patients and the public, and by poli... Read More about What is the Definition of Cure in Non-small Cell Lung Cancer?.

Improved survival outcomes despite older age at diagnosis: an era‐by‐era analysis of patients with primary central nervous system lymphoma treated at a single referral centre in the United Kingdom (2021)
Journal Article
Kaji, F. A., Martinez‐Calle, N., Bishton, M. J., Figueroa, R., Adlington, J., O’Donoghue, M., …Fox, C. P. (2021). Improved survival outcomes despite older age at diagnosis: an era‐by‐era analysis of patients with primary central nervous system lymphoma treated at a single referral centre in the United Kingdom. British Journal of Haematology, 195(4), 561-570. https://doi.org/10.1111/bjh.17747

Observational studies with long-term follow-up of patients with primary central nervous system lymphoma (PCNSL) are scarce. Patient data over a period of four decades were retrospectively analysed from databases at Not-tingham University Hospitals Tr... Read More about Improved survival outcomes despite older age at diagnosis: an era‐by‐era analysis of patients with primary central nervous system lymphoma treated at a single referral centre in the United Kingdom.

Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial (2021)
Journal Article
Liu, X., Shaw, R. H., Stuart, A. S. V., Greenland, M., Aley, P. K., Andrews, N. J., …Allen, L. (2021). Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial. Lancet, 398(10303), 856-869. https://doi.org/10.1016/S0140-6736%2821%2901694-9

Background: Use of heterologous prime-boost COVID-19 vaccine schedules could facilitate mass COVID-19 immunisation. However, we have previously reported that heterologous schedules incorporating an adenoviral vectored vaccine (ChAdOx1 nCoV-19, AstraZ... Read More about Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial.

Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India (2021)
Journal Article
Kulkarni, M. M., Kamath, A., Kamath, V. G., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (2021). Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India. PLoS ONE, 16(8), Article e0253593. https://doi.org/10.1371/journal.pone.0253593

Background Exposure to tobacco imagery in films causes young people to start smoking. Popular Indian films contain high levels of tobacco imagery, but those that do are required by law to display onscreen health warnings when smoking imagery occurs a... Read More about Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India.

Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial (2021)
Journal Article
Ussher, M., Best, C., Lewis, S., McKell, J., Coleman, T., Cooper, S., …Bauld, L. (2021). Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial. Trials, 22(1), Article 512. https://doi.org/10.1186/s13063-021-05480-6

Background: Financial incentives are an effective way of helping women to stop smoking during pregnancy. Unfortunately, most women who stop smoking at this time return to smoking within 12 months of the infant’s birth. There is no evidence for interv... Read More about Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial.

The Impact of Environmental Sustainability Labels on Willingness-to-Pay for Foods: A Systematic Review and Meta-Analysis of Discrete Choice Experiments (2021)
Journal Article
Bastounis, A., Buckell, J., Hartmann-Boyce, J., Cook, B., King, S., Potter, C., …Jebb, S. A. (2021). The Impact of Environmental Sustainability Labels on Willingness-to-Pay for Foods: A Systematic Review and Meta-Analysis of Discrete Choice Experiments. Nutrients, 13(8), Article 2677. https://doi.org/10.3390/nu13082677

Food production is a major contributor to environmental damage. More environmentally sustainable foods could incur higher costs for consumers. In this review, we explore whether consumers are willing to pay (WTP) more for foods with environmental sus... Read More about The Impact of Environmental Sustainability Labels on Willingness-to-Pay for Foods: A Systematic Review and Meta-Analysis of Discrete Choice Experiments.

Was the implementation of standardised tobacco packaging legislation in England associated with changes in smoking prevalence? A segmented regression analysis between 2006 and 2019 (2021)
Journal Article
Opazo Breton, M., Britton, J., Brown, J., Beard, E., & Bogdanovica, I. (2021). Was the implementation of standardised tobacco packaging legislation in England associated with changes in smoking prevalence? A segmented regression analysis between 2006 and 2019. Tobacco Control, https://doi.org/10.1136/tobaccocontrol-2021-056694

Background and aim In 2016, England initiated the implementation of standardised tobacco packaging, introduced in conjunction with minimum pack sizes and other measures included in the 2014 European Tobacco Products Directive, over the course of a 1-... Read More about Was the implementation of standardised tobacco packaging legislation in England associated with changes in smoking prevalence? A segmented regression analysis between 2006 and 2019.