All Outputs (178)

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article

Objective: To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care. Design: Randomised controlled trial. Setting: Participant... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED) (2023)
Journal Article

Background. The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial (RCT) showed no measurable be... Read More about The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED).

The impact of ageing on adults with cerebral palsy (2023)
Journal Article

Background Cerebral palsy (CP) is one of the most common neurological disorders in children and results in lifelong physical impairments. Adults with CP have approximately the same life expectancy as their non-disabled peers, so helping them to stay... Read More about The impact of ageing on adults with cerebral palsy.

The use of non‐invasive brain stimulation techniques to reduce body weight and food cravings: A systematic review and meta‐analysis (2023)
Journal Article

Several studies demonstrated non‐invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are safe and simple techniques that can reduce body weight, food cravings... Read More about The use of non‐invasive brain stimulation techniques to reduce body weight and food cravings: A systematic review and meta‐analysis.

Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams (2023)
Journal Article

Objectives: In the UK, over 20% of stroke survivors leave hospital with severe disability. Limited evidence-based clinical guidance is available to support the rehabilitation of these individuals. Our previous research has focussed on establishing co... Read More about Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams.

Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review (2023)
Journal Article

Introduction Osteoarthritis (OA) results from various aetiologies, including joint morphology, biomechanics, inflammation, and injury. The latter is implicated in post-traumatic OA, which offers a paradigm to identify potential biomarkers enabling e... Read More about Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review.

The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease (2023)
Journal Article

Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have develo... Read More about The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.

The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease (2023)
Journal Article

Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have develop... Read More about The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease.

The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease (2023)
Journal Article

Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have deve... Read More about The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.

Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research (2023)
Journal Article

Within the UK Armed Forces, musculoskeletal injuries account for over half of all medical downgrades and discharges. Data from other Armed Forces show that osteoarthritis (OA), more common in military personnel, is likely to contribute to this, both... Read More about Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research.

Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players (2023)
Journal Article

Importance Although professional soccer players appear to be at higher risk of neurodegenerative disease, the reason remains unknown. Objective To examine whether heading frequency is associated with risk of cognitive impairment in retired profe... Read More about Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players.

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article

Purpose To investigate the longitudinal associations between pain and depressive symptoms in adults. Methods Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data (2023)
Journal Article

Objective: Despite the prevalence of osteoarthritis (OA) in England, few studies have examined the health economic impact of chronic pain associated with OA. The aim of this study was to compare outcomes in patients with moderate-to-severe chronic pa... Read More about Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data.

Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database. (2023)
Journal Article

Background The burden of osteoarthritis (OA) in UK primary care has not been investigated thoroughly. Aim To estimate healthcare use and mortality in people with OA (overall and joint specific). Design and setting A matched cohort study of adul... Read More about Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database..

Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data (2023)
Journal Article

Background: Comorbidities are common in patients with osteoarthritis (OA). This study aimed to determine the association of a wide range of previously diagnosed comorbidities in adults with newly diagnosed OA compared with matched controls without OA... Read More about Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data.

Characterization of a Helicobacter pylori strain with high biofilm-forming ability (2023)
Journal Article

Introduction. Helicobacter pylori is highly polymorphic, and some strains are much more likely to cause disease than others. Biofilm formation can help bacteria to survive antibiotic treatment, immune attack and other stresses, promoting persistent i... Read More about Characterization of a Helicobacter pylori strain with high biofilm-forming ability.

Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study (2023)
Journal Article

Background Previous studies based on death certificates have found professional soccer players were more likely to die with neurodegenerative diseases, including dementia. Therefore, this study aimed to investigate whether retired professional male... Read More about Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study.

"Crack on": a qualitative study of care home managers experiences and responses to system-led setbacks during the crisis of the COVID- 19 Pandemic in England (2023)
Journal Article

Objectives: To explore care home managers’ experiences of systems working with various organisations, including statutory, third sector and private, during the second wave of the COVID-19 pandemic from Sept 2020 to April 2021 Design: An exploratory q... Read More about "Crack on": a qualitative study of care home managers experiences and responses to system-led setbacks during the crisis of the COVID- 19 Pandemic in England.

Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts (2023)
Journal Article

Background/Objectives: Ataxia telangiectasia (A‐T) is a multiorgan disorder with increased vulnerability to cancer. Despite this increased cancer risk, there are no widely accepted guidelines for cancer surveillance in people affected by A‐T. We aime... Read More about Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts.

Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting (2023)
Journal Article

INTRODUCTION: Older people were at particular risk of morbidity and mortality during COVID-19. Consequently, they experienced formal (externally imposed) and informal (self-imposed) periods of social isolation and quarantine. This is hypothesised to... Read More about Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting.