Preview of the Lung Science Conference 2024
(2023)
Journal Article
All Outputs (236)
‘Project period’: a workplace health promotion innovation in a higher education setting (2023)
Journal Article
Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies (2023)
Journal Article
Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that protects the brain and spinal cord against mechanical shock, provides buoyancy, clears metabolic waste and transports extracellular components to remote sites in t... Read More about Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies.
Risk of alcohol-related liver disease in the offspring of parents with alcohol-related liver disease: A nationwide cohort study (2023)
Journal Article
Background and aims: Offspring of patients with alcohol-related liver disease (ALD) may have higher risk of ALD. We examined their risk of ALD and survival with ALD. Approach & Results: We used Danish nationwide registries to identify offspring of... Read More about Risk of alcohol-related liver disease in the offspring of parents with alcohol-related liver disease: A nationwide cohort study.
Presentation and publication skills: How to review a paper (2023)
Journal Article
We provide comprehensive insights into the peer review process and guide potential reviewers through the steps of reviewing scientific manuscripts. We discuss essential aspects such as the reviewer’s responsibility in responding to invitations and ma... Read More about Presentation and publication skills: How to review a paper.
ESPEN practical guideline on clinical nutrition in acute and chronic pancreatitis (2023)
Journal Article
Both acute and chronic pancreatitis are frequent diseases of the pancreas, which, despite being of benign nature, are related to a significant risk of malnutrition and may require nutritional support. Acute necrotizing pancreatitis is encountered in... Read More about ESPEN practical guideline on clinical nutrition in acute and chronic pancreatitis.
Temporal trends and patterns in initial opioid prescriptions after hospital discharge following colectomy in England over 10 years (2023)
Journal Article
Background While opioid analgesics are often necessary for the management of acute postoperative pain, appropriate prescribing practices are crucial to avoid harm. The aim was to investigate the changes in the proportion of people receiving initial... Read More about Temporal trends and patterns in initial opioid prescriptions after hospital discharge following colectomy in England over 10 years.
Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review (2023)
Journal Article
Coronavirus disease 2019 (COVID-19) can lead to ongoing symptoms such as breathlessness, fatigue and muscle pain, which can have a substantial impact on an individual. Exercise-based rehabilitation programmes have proven beneficial in many long-term... Read More about Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review.
Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study (2023)
Journal Article
Can angiotropism and lymphovascular invasion refine the current cutaneous melanoma staging system? (2023)
Journal Article
Background: Several prognostic factors for primary cutaneous melanoma (PCM) have been identified, and these predict metastasis and survival, to a certain extent. We sought to determine the frequency of angiotropism (AT) and lymphovascular invasion (L... Read More about Can angiotropism and lymphovascular invasion refine the current cutaneous melanoma staging system?.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth (2023)
Journal Article
Acute myeloid leukemia (AML) is a heterogeneous disease caused by different mutations. Previously, we showed that each mutational subtype develops its specific gene regulatory network (GRN) with transcription factors interacting within multiple gene... Read More about Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Mathematical modelling and deep learning algorithms to automate assessment of single and digitally multiplexed immunohistochemical stains in tumoural stroma (2023)
Journal Article
Whilst automated analysis of immunostains in pathology research has focused predominantly on the epithelial compartment, automated analysis of stains in the stromal compartment is challenging and therefore requires time-consuming pathological input a... Read More about Mathematical modelling and deep learning algorithms to automate assessment of single and digitally multiplexed immunohistochemical stains in tumoural stroma.
Understanding recent advances in genomic testing in paediatric oncology (2023)
Journal Article
Advancements in genomics have had a significant impact on our ability to diagnose and treat several health conditions, notably cancer. In this article, we discuss the evolution of genomic methods from the early first-generation genome sequencing meth... Read More about Understanding recent advances in genomic testing in paediatric oncology.
Quantitative expression of oestrogen receptor in breast cancer: Clinical and molecular significance (2023)
Journal Article
Background Oestrogen receptor (ER) positive breast cancer (BC) patients are eligible for endocrine therapy (ET), regardless of ER immunohistochemical expression level. There is a wide spectrum of ER expression and the response to ET is not uniform... Read More about Quantitative expression of oestrogen receptor in breast cancer: Clinical and molecular significance.
Regional variations and deprivation are linked to poorer access to laparoscopic and robotic colorectal surgery: a national study in England (2023)
Journal Article
Background: Laparoscopic and now robotic colorectal surgery has rapidly increased in prevalence; however, little is known about how uptake varies by region and sociodemographics. The aim of this study was to quantify the uptake of minimally invasive... Read More about Regional variations and deprivation are linked to poorer access to laparoscopic and robotic colorectal surgery: a national study in England.
Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease (2023)
Journal Article
BACKGROUND: The combination of ibrutinib and venetoclax has been shown to improve outcomes in patients with chronic lymphocytic leukemia (CLL) as compared with chemoimmunotherapy. Whether ibrutinib-venetoclax and personalization of treatment duration... Read More about Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease.
Richter's transformation: Transforming the clinical landscape (2023)
Journal Article
Richter transformation (RT) represents an aggressive histological transformation from chronic lymphocytic leukaemia, most often to a large B cell lymphoma. It is characterised by chemo-resistance and subsequent short survival. Drug development has st... Read More about Richter's transformation: Transforming the clinical landscape.
The amino acid transporter SLC7A11 expression in breast cancer (2023)
Journal Article
Breast cancer (BC), characterized by its diverse molecular profiles and clinical outcomes, presents a significant challenge in the development of effective therapeutic strategies. Metabolic reprogramming, a defining characteristic of cancer, has emer... Read More about The amino acid transporter SLC7A11 expression in breast cancer.
Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke (2023)
Journal Article
Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study explored wh... Read More about Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke.