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All Outputs (279)

Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study (2024)
Journal Article
Killan, C. F., Hoare, D. J., Hartley, D. E. H., Church, P., Isherwood, F., Nasim, S., …Kitterick, P. T. (in press). Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2023-326055

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., …Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.

Transgender and gender diverse older people: health, aging and dementia (2024)
Journal Article
Asti, E., Beale, N., Thorne, N., & Dening, T. (2024). Transgender and gender diverse older people: health, aging and dementia. International Journal of Transgender Health, https://doi.org/10.1080/26895269.2024.2355232

Background and Objectives 262,000 people in the UK identify as transgender and gender diverse (TGD), and this population is believed to be growing. As the population is aging, an increase in older TGD people accessing health and social care can be a... Read More about Transgender and gender diverse older people: health, aging and dementia.

Systematic Review and Meta-Analysis: Relative age in Attention-Deficit/ Hyperactivity Disorder and Autism Spectrum Disorder (2024)
Journal Article
Frisira, E., Holland, J., & Sayal, K. (2024). Systematic Review and Meta-Analysis: Relative age in Attention-Deficit/ Hyperactivity Disorder and Autism Spectrum Disorder. European Child and Adolescent Psychiatry, https://doi.org/10.1007/s00787-024-02459-x

Youngest students in their class, with birthdates just before the school entry cut-off date, are overrepresented among children receiving an Attention-Deficit/Hyperactivity Disorder (ADHD) diagnosis or medication for this. This is known as the relati... Read More about Systematic Review and Meta-Analysis: Relative age in Attention-Deficit/ Hyperactivity Disorder and Autism Spectrum Disorder.

Pathways between digital activity and depressed mood in adolescence: Outlining a developmental model integrating risk, reactivity, resilience and reciprocity (2024)
Journal Article
Sonuga-Barke, E. J. S., Stoilova, M., Kostyrka-Allchorne, K., Bourgaize, J., Murray, A., Tan, M. P. J., …Livingstone, S. (in press). Pathways between digital activity and depressed mood in adolescence: Outlining a developmental model integrating risk, reactivity, resilience and reciprocity. Current Opinion in Behavioral Sciences,

A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project (2024)
Journal Article
Routen, A. C., Cale, L., Chalkley, A. E., Clemes, S., Edwardson, C. L., Glazebrook, C., …Sherar, L. B. (2024). A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project. Translational Journal of the American College of Sports Medicine, 9(2), Article e000261. https://doi.org/10.1249/tjx.0000000000000261

Purpose To determine the a) implementation of CLASS PAL (Physically Active Learning), b) implementation process of CLASS PAL, and c) influence of the inner setting (i.e., school) and individuals (teachers and pupils) on the implementation of CLASS PA... Read More about A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project.

Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function (2024)
Journal Article
Hashmat, A., Ya, J., Kadir, R., Alwjwaj, M., & Bayraktutan, U. (2024). Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function. Tissue Barriers, Article 2350821. https://doi.org/10.1080/21688370.2024.2350821

Breakdown of blood-brain barrier (BBB) represents a key pathology in hyperglycemia-mediated cerebrovascular damage after an ischemic stroke. As changes in the level and nature of vasoactive agents released by endothelial cells (ECs) may contribute to... Read More about Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function.

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact (2024)
Journal Article
Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., …Ismail, O. (2024). The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, https://doi.org/10.1002/alz.13836

Two of every three persons living with dementia reside in low‐ and middle‐income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs oc... Read More about The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact.

Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol (2024)
Journal Article
Chouliara, N., Cameron, T., Ballard-Ridley, S., Fisher, R. J., Kettlewell, J., Kidd, L., …Gordon, A. L. (2024). Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol. Healthcare, 12(10), Article 1027. https://doi.org/10.3390/healthcare12101027

Telerehabilitation (TR) shows promise as a method of remote service delivery, yet there is little guidance to inform implementation in the context of the National Health Service (NHS) in England. This paper presents the protocol for a realist synthes... Read More about Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol.

Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial (2024)
Journal Article
Andrén, P., Sampaio, F., Ringberg, H., Wachtmeister, V., Warnström, M., Isomura, K., …Mataix-Cols, D. (2024). Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial. JAMA Network Open, 7(5), Article e248468. https://doi.org/10.1001/jamanetworkopen.2024.8468

Importance: Behavior therapy is a recommended intervention for Tourette syndrome (TS) and chronic tic disorder (CTD), but availability is limited and long-term effects are uncertain. Objective: To investigate the long-term efficacy and cost-effec... Read More about Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial.

Dysphagia after stroke: research advances in treatment interventions (2024)
Journal Article
Labeit, B., Michou, E., Trapl-Grundschober, M., Suntrup-Krueger, S., Muhle, P., Bath, P. M., & Dziewas, R. (2024). Dysphagia after stroke: research advances in treatment interventions. Lancet Neurology, 23(4), 418-428. https://doi.org/10.1016/s1474-4422%2824%2900053-x

After a stroke, most patients have dysphagia, which can lead to aspiration pneumonia, malnutrition, and adverse functional outcomes. Protective interventions aimed at reducing these complications remain the cornerstone of treatment. Dietary adjustmen... Read More about Dysphagia after stroke: research advances in treatment interventions.

Age Deficits in Associative Memory are not Alleviated by Multisensory Paradigms (2024)
Journal Article
Badham, S. P., Atkin, C., Stacey, J. E., Henshaw, H., Allen, H. A., & Roberts, K. L. (2024). Age Deficits in Associative Memory are not Alleviated by Multisensory Paradigms. Journals of Gerontology, Series B, https://doi.org/10.1093/geronb/gbae063

Objectives Age deficits in memory are widespread, this impacts individuals at a personal level, and investigating memory has been a key focus in cognitive ageing research. Age deficits occur in memory for an episode, where information from the envir... Read More about Age Deficits in Associative Memory are not Alleviated by Multisensory Paradigms.

Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives (2024)
Journal Article
Tucker, R., Vickers, R., Adams, E. J., Burgon, C., Lock, J., Goldberg, S. E., …Harwood, R. H. (2024). Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives. Archives of Public Health, 82(1), Article 54. https://doi.org/10.1186/s13690-024-01283-8

Background Despite several interventions demonstrating benefit to people living with dementia and their caregivers, few have been translated and implemented in routine clinical practice. There is limited evidence of the barriers and facilitators for... Read More about Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives.

Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies (2024)
Journal Article
Lim, A., Ma, H., Johnston, S. C., Singhal, S., Muthusamy, S., Wang, Y., …Phan, T. G. (2024). Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies. Journal of the American Heart Association, 13(9), Article e032471. https://doi.org/10.1161/jaha.123.032471

Background Risk of recurrence after minor ischemic stroke is usually reported with transient ischemic attack. No previous meta‐analysis has focused on minor ischemic stroke alone. The objective was to evaluate the pooled proportion of 90‐day stroke r... Read More about Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies.

Gradient boosted decision trees reveal nuances of auditory discrimination behavior (2024)
Journal Article
Griffiths, C. S., Lebert, J. M., Sollini, J., & Bizley, J. K. (2024). Gradient boosted decision trees reveal nuances of auditory discrimination behavior. PLoS Computational Biology, 20(4), Article e1011985. https://doi.org/10.1371/journal.pcbi.1011985

Animal psychophysics can generate rich behavioral datasets, often comprised of many 1000s of trials for an individual subject. Gradient-boosted models are a promising machine learning approach for analyzing such data, partly due to the tools that all... Read More about Gradient boosted decision trees reveal nuances of auditory discrimination behavior.

When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial) (2024)
Journal Article
Brown, S., Ploeger, C., Petersen, J. J., Guo, B., Beckenstrom, A. C., Petersen, J. J., …Morriss, R. (2024). When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial). Comprehensive Psychiatry, 132, Article 152467. https://doi.org/10.1016/j.comppsych.2024.152467

Background A RCT of a novel intervention to detect antidepressant medication response (the PReDicT Test) took place in five European countries, accompanied by a nested study of its acceptability and implementation presented here. The RCT results i... Read More about When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial).

Objective QC for diffusion MRI data: artefact detection using normative modelling (2024)
Journal Article
Cirstian, R., Forde, N. J., Andersson, J. L., Sotiropoulos, S. N., Beckmann, C. F., & Marquand, A. F. (2024). Objective QC for diffusion MRI data: artefact detection using normative modelling. Imaging Neuroscience, 2, 1-14. https://doi.org/10.1162/imag_a_00144

Diffusion MRI is a neuroimaging modality used to evaluate brain structure at a microscopic level and can be exploited to map white matter fibre bundles and microstructure in the brain. One common issue is the presence of artefacts, such as acquisitio... Read More about Objective QC for diffusion MRI data: artefact detection using normative modelling.

Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications (2024)
Journal Article
Woods, J. G., Achten, E., Asllani, I., Bolar, D. S., Dai, W., Detre, J. A., …the ISMRM Perfusion Study Group. (2024). Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications. Magnetic Resonance in Medicine, https://doi.org/10.1002/mrm.30091

Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic processes involved in various neurological disorders and guiding clinical decision-making. This guidelines article provides a comprehensive overview of quantitative... Read More about Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications.