All Outputs (131)

Developmental student support in undergraduate medical education: AMEE Guide No. 92 (2014)
Journal Article

Developmental student support has a focus on developing the whole person, not only academic and clinical competence. The positive and proactive developmental approach is in marked contrast to the deficit and reactive approach to student support which... Read More about Developmental student support in undergraduate medical education: AMEE Guide No. 92.

How do surgeons and anaesthetists make decisions about surgery for patients who are frail, and what factors influence these decisions? (2014)
Journal Article

Auditory network connectivity in tinnitus patients: a resting-state fMRI study (2014)
Journal Article

Objective: Resting-state functional magnetic resonance imaging (fMRI) uncovers correlated activity between spatially distinct functionally related brain regions and offers clues about the integrity of functional brain circuits in people with chronic... Read More about Auditory network connectivity in tinnitus patients: a resting-state fMRI study.

Reappraising the long-term course and outcome of psychotic disorders: the AESOP-10 study (2014)
Journal Article

When is birthweight at term abnormally low?: a systematic review and meta-analysis of the association and predictive ability of current birthweight standards for neonatal outcomes (2014)
Journal Article

Background Intrauterine growth restriction is a cause of neonatal morbidity and mortality. A variety of definitions of low birthweight are used in clinical practice, with a lack of consensus regarding which definitions best predict adverse outcomes.... Read More about When is birthweight at term abnormally low?: a systematic review and meta-analysis of the association and predictive ability of current birthweight standards for neonatal outcomes.

Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders. (2014)
Journal Article

Background: Childhood abuse is considered one of the main environmental risk factors for the development of psychotic symptoms and disorders. However, this association could be due to genetic factors influencing exposure to such risky environments or... Read More about Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders..

The prevalence of tinnitus and the relationship with neuroticism in a middle-aged UK population (2014)
Journal Article

Background: Previous research has suggested that a substantial proportion of the population are severely affected by tinnitus, however recent population data are lacking. Furthermore, there is growing evidence that the perception of severity is close... Read More about The prevalence of tinnitus and the relationship with neuroticism in a middle-aged UK population.

The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology (2013)
Journal Article

Aim The Cochrane Skin Group (CSG) is part of the international Cochrane Collaboration (http://www.cochrane.org/). The CSG prepares, maintains and disseminates high quality evidence-based summaries on the prevention, diagnosis and treatment of skin d... Read More about The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology.

Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10 (2013)
Journal Article

There is growing interest in myeloid (my) dendritic cells (DC) as an alternative to monocyte-derived DC (moDC) for immunotherapy. However, in contrast to moDC, little is known regarding the effect of malignancy on the function, abundance or use of in... Read More about Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10.

Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies (2013)
Journal Article

Background The most important challenge of performing insitu transcriptional profiling of the human ocular surface epithelial regions is obtaining samples in sufficient amounts, without contamination from adjacent tissue, as the region of interest i... Read More about Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies.

Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool (2013)
Journal Article

The Management Standards Indicator Tool (MSIT) is a 35-item self-report measure of the psychosocial work environment designed to assist organizations with psychosocial risk assessment. It is also used in work environment research. Edwards and Webster... Read More about Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool.

Report of the first veterinary student support workshop (2013)
Journal Article

Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol (2013)
Journal Article

Background The prevalence of tobacco smoking among homeless people can reach more than 90%, with related morbidity and mortality being high. However, research in this area is scarce. This study aims to explore smoking and quitting related behaviours... Read More about Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol.

Menopause and work: an electronic survey of employees’ attitudes in the UK (2013)
Journal Article

Objectives: This study explored women's experiences of working through menopausal transition in the UK. It aimed to identify the perceived effects of menopausal symptoms on working life, to outline the perceived effects of work on menopausal symptoms... Read More about Menopause and work: an electronic survey of employees’ attitudes in the UK.

Development of a new SonovueTM contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding (2013)
Journal Article

Compromised limb blood flow in aging may contribute to the development of sarcopenia, frailty, and the metabolic syndrome. We developed a novel contrast-enhanced ultrasound technique using Sonovue™ to characterize muscle microvasculature responses to... Read More about Development of a new SonovueTM contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding.

Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis (2013)
Journal Article

C. difficile infection (CDI) is rarely reported in cystic fibrosis (CF) patients despite frequent hospitalisations and antibiotic usage. Conversely, the prevalence of CDI in inflammatory bowel disease (IBD) has received increased attention. We inve... Read More about Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis.

Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI (2013)
Journal Article

Ex vivo rodent lung models are explored for physiological measurements of respiratory function with hyperpolarized (hp) 129Xe MRI. It is shown that excised lung models allow for simplification of the technical challenges involved and provide valuable... Read More about Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI.

Neural primacy of the salience processing system in schizophrenia (2013)
Journal Article

For effective information processing, two large-scale distributed neural networks appear to be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (DLPFC) and a salience system anchored on the anterior insula. Aberr... Read More about Neural primacy of the salience processing system in schizophrenia.

A survey of tobacco dependence treatment guidelines in 121 countries (2013)
Journal Article

Aims To report progress among Parties to the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in developing national tobacco treatment guidelines in accordance with FCTC Article 14 guideline recommendations. Design... Read More about A survey of tobacco dependence treatment guidelines in 121 countries.

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More about Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics.