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All Outputs (131)

Risk factors associated with oral Human Papillomavirus (HPV) prevalence within a young adult population (2024)
Journal Article

Background: The prevalence of, and risk factors for, genital Human Papillomavirus (HPV) infections within the young adult population are well-established; the same is not known for oral HPV. This observational study aimed to determine oral HPV preval... Read More about Risk factors associated with oral Human Papillomavirus (HPV) prevalence within a young adult population.

An In Vivo and In Silico Approach Reveals Possible Sodium Channel Nav1.2 Inhibitors from Ficus religiosa as a Novel Treatment for Epilepsy (2024)
Journal Article

Epilepsy is a neurological disease that affects approximately 50 million people worldwide. Despite an existing abundance of antiepileptic drugs, lifelong disease treatment is often required but could be improved with alternative drugs that have fewer... Read More about An In Vivo and In Silico Approach Reveals Possible Sodium Channel Nav1.2 Inhibitors from Ficus religiosa as a Novel Treatment for Epilepsy.

Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST (2024)
Journal Article

Blood Pressure Variability (BPV) is associated with cardiovascular risk and serum uric acid level. We investigated whether BPV was lowered by allopurinol and whether it was related to neuroimaging markers of cerebral small vessel disease (CSVD) and c... Read More about Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST.

Leave no one behind: A global survey of the current state of geriatric oncology practice by SIOG national representatives (2024)
Journal Article

Introduction The Sustainable Development Goals of the United Nations include a commitment to “leave no one behind” as a universal goal. To achieve this in geriatric oncology (GO) worldwide, it is important to understand the current state of GO at an... Read More about Leave no one behind: A global survey of the current state of geriatric oncology practice by SIOG national representatives.

Factors influencing older women's decision‐making related to treatment of operable breast cancer: A qualitative systematic review (2024)
Journal Article

Objective: There is variation in practice in the treatment of older women with breast cancer. International guidelines highlight the importance of patient autonomy in treatment decision‐making. The aim of this study is to identify factors which influ... Read More about Factors influencing older women's decision‐making related to treatment of operable breast cancer: A qualitative systematic review.

The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease (2024)
Journal Article

This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physica... Read More about The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease.

Quality of work life and job satisfaction among early-career pharmacists in Africa’s most populous country: A nationwide survey in Nigeria (2023)
Journal Article

This study examined the factors affecting the quality of work life and job satisfaction among early-career pharmacists in Nigeria. This was a cross-sectional survey conducted across the six geopolitical zones in Nigeria. We used the database of licen... Read More about Quality of work life and job satisfaction among early-career pharmacists in Africa’s most populous country: A nationwide survey in Nigeria.

Treatment and outcomes in breast cancer patients: A cross section study from the EUSOMA breast centre network (2023)
Journal Article

Introduction The present study was designed to describe tumour features and treatments for patients with breast cancer. It also aimed at assessing the risk of distant metastases in relation to biological profiles, disease stages and treatment. Meth... Read More about Treatment and outcomes in breast cancer patients: A cross section study from the EUSOMA breast centre network.

Assessing the impact of COVID-19 on prescription patterns and antibiotic use: Insights from three military health facilities (2023)
Journal Article

Background: The COVID-19 pandemic disrupted health systems globally and there are suggestions it impacted antibiotics prescribing patterns in clinical practice. Objectives: This study aimed to assess the effects of the COVID-19 pandemic on the prescr... Read More about Assessing the impact of COVID-19 on prescription patterns and antibiotic use: Insights from three military health facilities.

Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women (2023)
Journal Article

Studies examining the effect of protein (PRO) feeding on post resistance exercise (RE) muscle protein synthesis (MPS) have primarily been performed in men, and little evidence is available regarding the quantity of PRO required to maximally stimulate... Read More about Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women.

Assessing patient-reported outcomes (PROs) and patient-related outcomes in randomized cancer clinical trials for older adults: Results of DATECAN-ELDERLY initiative (2023)
Journal Article

As older adults with cancer are underrepresented in randomized clinical trials (RCT), there is limited evidence on which to rely for treatment decisions for this population. Commonly used RCT endpoints for the assessment of treatment efficacy are mor... Read More about Assessing patient-reported outcomes (PROs) and patient-related outcomes in randomized cancer clinical trials for older adults: Results of DATECAN-ELDERLY initiative.

Risk perception and hesitancy towards malaria vaccines among hospital pharmacists in southeast Nigeria: a cross-sectional study (2023)
Journal Article

This study evaluated the willingness and perceived concerns of hospital pharmacists in allowing and recommending malaria vaccines. This was a cross-sectional-based study. Participants were recruited from two teaching hospitals in southeast Nigeria –... Read More about Risk perception and hesitancy towards malaria vaccines among hospital pharmacists in southeast Nigeria: a cross-sectional study.

Effectiveness of educational interventions on hypertensive patients' self-management behaviours: an umbrella review protocol (2023)
Journal Article

Background: Although different educational interventions have been widely used to manage and treat hypertension, alone or in combination with other interventions, there is a significant variation in their claimed effectiveness. Review question/obj... Read More about Effectiveness of educational interventions on hypertensive patients' self-management behaviours: an umbrella review protocol.

Beyond Patient Characteristics: A Narrative Review of Contextual Factors Influencing Involuntary Admissions in Mental Health Care (2023)
Journal Article

Variations in the rates of involuntary admission (IA) reflect the influence of unexplained contextual variables that are typically too heterogeneous to be included in systematic reviews. This paper attempts to gather and analyze factors unrelated to... Read More about Beyond Patient Characteristics: A Narrative Review of Contextual Factors Influencing Involuntary Admissions in Mental Health Care.

Are Therapies That Target α-Synuclein Effective at Halting Parkinson’s Disease Progression? A Systematic Review (2023)
Journal Article

There are currently no pharmacological treatments available that completely halt or reverse the progression of Parkinson’s Disease (PD). Hence, there is an unmet need for neuroprotective therapies. Lewy bodies are a neuropathological hallmark of PD a... Read More about Are Therapies That Target α-Synuclein Effective at Halting Parkinson’s Disease Progression? A Systematic Review.