All Outputs (516)

Being the ‘med reg’: an exploration of junior doctors’ perceptions of the medical registrar role (2017)
Journal Article
Fisher, J. M., Garside, M. J., Brock, P., Gibson, V., Hunt, K., Wyrko, Z., & Gordon, A. L. (2017). Being the ‘med reg’: an exploration of junior doctors’ perceptions of the medical registrar role. Journal of the Royal College of Physicians of Edinburgh, 47(1), https://doi.org/10.4997/JRCPe.2017.116

The role of the medical registrar is a challenging one and is acknowledged as being a disincentive to a career in medicine for some junior doctors. We set out to build a broader understanding of the role through exploration of Foundation Doctors’ and... Read More about Being the ‘med reg’: an exploration of junior doctors’ perceptions of the medical registrar role.

A low cost virtual reality system for home based rehabilitation of the arm following stroke: a randomised controlled feasibility trial (2017)
Journal Article
Standen, P., Threapleton, K., Richardson, A., Connell, L., Brown, D., Battersby, S., …Burton, A. (2017). A low cost virtual reality system for home based rehabilitation of the arm following stroke: a randomised controlled feasibility trial. Clinical Rehabilitation, 31(3), https://doi.org/10.1177/0269215516640320

OBJECTIVE: To assess the feasibility of conducting a randomised controlled trial of a home-based virtual reality system for rehabilitation of the arm following stroke. DESIGN: Two group feasibility randomised controlled trial of intervention versus... Read More about A low cost virtual reality system for home based rehabilitation of the arm following stroke: a randomised controlled feasibility trial.

Understanding the models of community hospital rehabilitation activity (MoCHA): a mixed method study (2017)
Journal Article
Gladman, J., Buckell, J., Young, J., Smith, A., Hulme, C., Saggu, S., …Tucker, H. (2017). Understanding the models of community hospital rehabilitation activity (MoCHA): a mixed method study. BMJ Open, 7(2), Article e010483. https://doi.org/10.1136/bmjopen-2015-010483

Introduction To understand the variation in performance between community hospitals, our objectives are: to measure the relative performance (cost efficiency) of rehabilitation services in community hospitals; to identify the characteristics of c... Read More about Understanding the models of community hospital rehabilitation activity (MoCHA): a mixed method study.

Why geriatric medicine? A survey of UK specialist trainees in geriatric medicine (2017)
Journal Article
Fisher, J. M., Garside, M. J., Brock, P., Gibson, V., Hunt, K. K., Briggs, S., & Gordon, A. L. (2017). Why geriatric medicine? A survey of UK specialist trainees in geriatric medicine. Age and Ageing, 46(4), 672-677. https://doi.org/10.1093/ageing/afx009

Background: There is global concern that there are insufficient numbers of geriatricians to meet the needs of the ageing population. A 2005 survey described factors that influenced why UK geriatricians had chosen to specialise in the field - in the d... Read More about Why geriatric medicine? A survey of UK specialist trainees in geriatric medicine.

The competencies of registered nurses working in care homes: a modified Delphi study (2017)
Journal Article
Stanyon, M., Goldberg, S. E., Astle, A., Griffiths, A., & Gordon, A. L. (2017). The competencies of registered nurses working in care homes: a modified Delphi study. Age and Ageing, 46(4), 582–588. https://doi.org/10.1093/ageing/afw244

BACKGROUND: Registered Nurses (RNs) working in UK care homes receive most of their training in acute hospitals. At present the role of care home nursing is underdeveloped and it is seen as a low status career. We describe here research to define cor... Read More about The competencies of registered nurses working in care homes: a modified Delphi study.

Acetylcholinesterase activity measurement and clinical features of delirium (2016)
Journal Article
Jackson, T., Moorey, H., Sheehan, B., Maclullich, A., Gladman, J., & Lord, J. (2017). Acetylcholinesterase activity measurement and clinical features of delirium. Dementia and Geriatric Cognitive Disorders, 43(1-2), https://doi.org/10.1159/000452832

Aims: Cholinergic deficiency is commonly implicated in the pathophysiology of delirium. We aimed to investigate the relationship between directly measured serum AChE activity and (1) clinical features of delirium and (2) outcomes, among older hospita... Read More about Acetylcholinesterase activity measurement and clinical features of delirium.

A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities (2016)
Conference Proceeding
Aslam, S., Standen, P., Shopland, N., & Burton, A. (2016). A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities. In Proceedings - 2016 International Conference on Interactive Technologies and Games (ITAG). https://doi.org/10.1109/iTAG.2016.9

Previous research has shown that the humanoid NAO robot can enhance learning as well as improve communication in children with intellectual disabilities. However, most special needs schools cannot afford the humanoid NAO robot due to high costs. Coul... Read More about A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities.

A study of the validity and the reliability of the Geriatric Anxiety Inventory in screening for anxiety after stroke in older inpatients (2016)
Journal Article
Kneebone, I. I., Fife-Schaw, C., Lincoln, N., & Harder, H. (2016). A study of the validity and the reliability of the Geriatric Anxiety Inventory in screening for anxiety after stroke in older inpatients. Clinical Rehabilitation, 30(12), https://doi.org/10.1177/0269215515619661

Objectives: To investigate the validity and reliability of the Geriatric Anxiety Inventory in screening for anxiety in older inpatients post-stroke. Design: Longitudinal. Subjects: A total of 81 inpatients with stroke aged 65 years or older we... Read More about A study of the validity and the reliability of the Geriatric Anxiety Inventory in screening for anxiety after stroke in older inpatients.

How to screen for non-adherence to antihypertensive therapy (2016)
Journal Article
Gupta, P., Patel, P., Horne, R., Buchanan, H., Williams, B., & Tomaszewski, M. (in press). How to screen for non-adherence to antihypertensive therapy. Current Hypertension Reports, 18(12), Article 88. https://doi.org/10.1007/s11906-016-0697-7

The quality of assessment of non-adherence to treatment in hypertensive is poor. Within this review, we discuss the different methods used to assess adherence to blood-pressure-lowering medications in hypertension patients. Subjective reports such as... Read More about How to screen for non-adherence to antihypertensive therapy.

A systematic review of peer mentoring interventions for people with traumatic brain injury (2016)
Journal Article
Morris, R., Fletcher-Smith, J. C., & Radford, K. (in press). A systematic review of peer mentoring interventions for people with traumatic brain injury. Clinical Rehabilitation, https://doi.org/10.1177/0269215516676303

Objective: This systematic review sought evidence concerning the effectiveness of peer mentoring for people with traumatic brain injury. Data sources: Fourteen electronic databases were searched, including PsycINFO, MEDLINE, CINAHL, EMBASE and the C... Read More about A systematic review of peer mentoring interventions for people with traumatic brain injury.

Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial (2016)
Journal Article
Bath, P. M., Appleton, J. P., Beridze, M., Christensen, H., Dineen, R. A., Duley, L., …Sprigg, N. (2017). Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial. International Journal of Stroke, 12(5), 524-538. https://doi.org/10.1177/1747493016677988

Background: The risk of recurrence following ischaemic stroke (IS) or transient ischaemic attack (TIA) is highest immediately after the event. Antiplatelet agents are effective in reducing the risk of recurrence and two agents are superior to one in... Read More about Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial.

Frailsafe: from conception to national breakthrough collaborative (2016)
Journal Article
Offord, N., Wyrko, Z., Downes, T., Hopper, A., Harriman, P., & Gordon, A. L. (2016). Frailsafe: from conception to national breakthrough collaborative. Acute Medicine, 15(3),

The number of people aged over 60 years worldwide is projected to rise from 605 million in 2000 to almost 2 billion by 2050, while those over 80 years will quadruple to 395 million. Two-thirds of UK acute hospital admissions are over 65, the highest... Read More about Frailsafe: from conception to national breakthrough collaborative.

Virtual rehabilitation: what are the practical barriers for home-based research? (2016)
Journal Article
Threapleton, K., Drummond, A. E., & Standen, P. (2016). Virtual rehabilitation: what are the practical barriers for home-based research?. Digital Health, 2, https://doi.org/10.1177/2055207616641302

Virtual reality technologies are becoming increasingly accessible and affordable to deliver, and consequently the interest in applying virtual reality within rehabilitation is growing. This has resulted in the emergence of research exploring the util... Read More about Virtual rehabilitation: what are the practical barriers for home-based research?.

New horizons: the management of hypertension in people with dementia (2016)
Journal Article
Harrison, J. K., Van Der Wardt, V., Conroy, S. P., Stott, D. J., Dening, T., Gordon, A. L., …Gladman, J. R. (2016). New horizons: the management of hypertension in people with dementia. Age and Ageing, 45(6), 740-746. https://doi.org/10.1093/ageing/afw155

The optimal management of hypertension in people with dementia is uncertain. This review explores if people with dementia experience greater adverse effects from antihypertensive medications, if cognitive function is protected or worsened by controll... Read More about New horizons: the management of hypertension in people with dementia.

The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency (2016)
Journal Article
Sahota, O., Pulikottil-Jacob, R., Marshall, F., Montgomery, A., Tan, W., Sach, T., …Waring, J. (in press). The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency. Age and Ageing, 46(1), https://doi.org/10.1093/ageing/afw149

Objective: To compare the clinical and cost-effectiveness of a Community In-reach Rehabilitation and Care Transition (CIRACT) service with the traditional hospital-based rehabilitation (THB-Rehab) service. Design: Pragmatic randomised controlled... Read More about The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency.

Bathing adaptations in the homes of older adults (BATH-OUT): protocol for a feasibility randomised controlled trial (RCT) (2016)
Journal Article
Whitehead, P. J., James, M., Belshaw, S., Dawson, T., Day, M. R., & Walker, M. F. (2016). Bathing adaptations in the homes of older adults (BATH-OUT): protocol for a feasibility randomised controlled trial (RCT). BMJ Open, 6(10), 1-7. https://doi.org/10.1136/bmjopen-2016-013448

Introduction The Care Act 2014 has placed a responsibility on local authorities in England to provide services that prevent deterioration and minimise the use of other health and social care services. Housing adaptations have been identified as 1 of... Read More about Bathing adaptations in the homes of older adults (BATH-OUT): protocol for a feasibility randomised controlled trial (RCT).

Histopathological subgroups in knee osteoarthritis (2016)
Journal Article
Wyatt, L., Morerton, B., Mapp, P. I., Wilson, D., Hill, R., Ferguson, E., …Walsh, D. A. (in press). Histopathological subgroups in knee osteoarthritis. Osteoarthritis and Cartilage, 25(1), https://doi.org/10.1016/j.joca.2016.09.021

Objective: Osteoarthritis (OA) is a heterogeneous, multi-tissue disease. We hypothesised that different histopathological features characterise different stages during knee OA progression, and that discrete subgroups can be defined based on validated... Read More about Histopathological subgroups in knee osteoarthritis.

Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization (2016)
Journal Article
Alshuft, H., Condon, L., Dineen, R. A., & Auer, D. P. (in press). Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization. PLoS ONE, 11(9), Article e0161687. https://doi.org/10.1371/journal.pone.0161687

Objective This study investigates associations between cortical thickness and pain duration, and central sensitization as markers of pain progression in painful knee osteoarthritis. Methods Whole brain cortical thickness and pressure pain th... Read More about Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization.

Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India (2016)
Journal Article
Liu, H., Lindley, R., Alim, M., Felix, C., Gandhi, D. B., Verma, S. J., …Jan, S. (2016). Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India. BMJ, 6(e01202), 1-8. https://doi.org/10.1136/bmjopen-2016-012027

Introduction We are undertaking a randomised controlled trial (fAmily led rehabiliTaTion aftEr stroke in INDia, ATTEND) evaluating training a family carer to enable maximal rehabilitation of patients with stroke-related disability; as a potentially a... Read More about Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India.

Granulocyte Colony Stimulating Factor and Physiotherapy after Stroke: Results of a Feasibility Randomised Controlled Trial: Stem Cell Trial of Recovery EnhanceMent after Stroke-3 (STEMS-3 ISRCTN16714730) (2016)
Journal Article
Sprigg, N., O’Connor, R., Woodhouse, L. J., Krishnan, K., England, T. J., Connell, L. A., …Bath, P. M. (2016). Granulocyte Colony Stimulating Factor and Physiotherapy after Stroke: Results of a Feasibility Randomised Controlled Trial: Stem Cell Trial of Recovery EnhanceMent after Stroke-3 (STEMS-3 ISRCTN16714730). PLoS ONE, 11(9), Article e0161359. https://doi.org/10.1371/journal.pone.0161359

Background Granulocyte-colony stimulating factor (G-CSF) mobilises endogenous haematopoietic stem cells and enhances recovery in experimental stroke. Recovery may also be dependent on an enriched environment and physical activity. G-CSF may have the... Read More about Granulocyte Colony Stimulating Factor and Physiotherapy after Stroke: Results of a Feasibility Randomised Controlled Trial: Stem Cell Trial of Recovery EnhanceMent after Stroke-3 (STEMS-3 ISRCTN16714730).