Skip to main content

Research Repository

Advanced Search

All Outputs (79)

Annual research review: Digital health interventions for children and young people with mental health problems: a systematic and meta-review (2016)
Journal Article
Hollis, C., Falconer, C. J., Martin, J. L., Whittington, C., Stockton, S., Glazebrook, C., & Davies, E. B. (in press). Annual research review: Digital health interventions for children and young people with mental health problems: a systematic and meta-review. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.12663

Digital health interventions (DHIs), including computer-assisted therapy, smartphone apps and wearable technologies, are heralded as having enormous potential to improve uptake and accessibility, efficiency, clinical effectiveness and personalisation... Read More about Annual research review: Digital health interventions for children and young people with mental health problems: a systematic and meta-review.

Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system (2016)
Journal Article
Man, K. K., Coghill, D., Chan, E. W., Lau, W. C., Hollis, C., Liddle, E., …Wong, I. C. (in press). Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system. Translational Psychiatry, 6, Article e956. https://doi.org/10.1038/tp.2016.216

Previous studies have suggested that risk of psychotic events may be increased in children exposed to methylphenidate (MPH). However, this risk has not been fully examined and the possibility of confounding factors has not been excluded. Patients age... Read More about Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system.

The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder (2016)
Journal Article
Groom, M. J., Young, Z., Hall, C. L., Gillott, A., & Hollis, C. (2016). The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder. Psychiatry Research, 243, https://doi.org/10.1016/j.psychres.2016.06.042

There is a clinical need for objective evidence-based measures that are sensitive and specific to ADHD when compared with other neurodevelopmental disorders. This study evaluated the incremental validity of adding an objective measure of activity and... Read More about The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder.

Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review (2016)
Journal Article
Whittington, C., Pennant, M., Kendall, T., Glazebrook, C., Trayner, P., Groom, M. J., …Hollis, C. (in press). Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review. Journal of Child Psychology and Psychiatry, 57(9), 988-1004. https://doi.org/10.1111/jcpp.12556

Background: Tourette syndrome (TS) and chronic tic disorder (CTD) affect 1–2% of children and young people, but the most effective treatment is unclear. To establish the current evidence base, we conducted a systematic review of interventions for ch... Read More about Practitioner review: Treatments for Tourette syndrome in children and young people: a systematic review.

Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs (2016)
Journal Article
Simons, L., Valentine, A. Z., Falconer, C. J., Groom, M., Daley, D., Craven, M. P., …Hollis, C. (2016). Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs. JMIR mHealth and uHealth, 4(1), Article e31. https://doi.org/10.2196/mhealth.5009

Background: Guidelines in the United Kingdom recommend that medication titration for attention deficit hyperactivity disorder (ADHD) should be completed within 4-6 weeks and include regular reviews. However, most clinicians think that weekly clinic c... Read More about Developing mHealth Remote Monitoring Technology for Attention Deficit Hyperactivity Disorder: A Qualitative Study Eliciting User Priorities and Needs.

The challenges of implementing ADHD clinical guidelines and research best evidence in routine clinical care settings: a Delphi survey and mixed-methods study (2016)
Journal Article
Hall, C. L., Taylor, J. A., Newell, K., Baldwin, L., Sayal, K., & Hollis, C. (2016). The challenges of implementing ADHD clinical guidelines and research best evidence in routine clinical care settings: a Delphi survey and mixed-methods study. BJPsych Open, 2(1), 25-31. https://doi.org/10.1192/bjpo.bp.115.002386

Background:The landmark US Multimodal Treatment of ADHD (MTA) study established the benefits of individualised medication titration and optimisation strategies to improve short- to medium-term outcomes in attention-deficit hyperactivity disorder (ADH... Read More about The challenges of implementing ADHD clinical guidelines and research best evidence in routine clinical care settings: a Delphi survey and mixed-methods study.

Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle (2016)
Journal Article
Hall, C. L., Selby, K., Guo, B., Valentine, A. Z., Walker, G. M., & Hollis, C. (2016). Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle. Child and Adolescent Mental Health, 21(3), 175-178. https://doi.org/10.1111/camh.12140

Background Diagnosing attention deficit/hyperactivity disorder (ADHD) in children and young people typically relies on clinical observation and subjective parent, teacher and self-reports. The subjective nature of reports combined with contradicto... Read More about Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle.

Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis (2016)
Journal Article
Hollis, C., Pennant, M., Cuenca, J., Glazebrook, C., Kendall, T., Whittington, C., …Stern, J. (2016). Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis. Health Technology Assessment, 20(4), 1-450. https://doi.org/10.3310/hta20040

Background: Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment. Ob... Read More about Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis.

The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review (2015)
Journal Article
Hall, C. L., Valentine, A., Groom, M. J., Walker, G. M., Sayal, K., Daley, D., & Hollis, C. (2016). The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review. European Child and Adolescent Psychiatry, 25(7), 677-699. https://doi.org/10.1007/s00787-015-0798-x

Attention deficit hyperactivity disorder (ADHD) is typically diagnosed using clinical observation and subjective informant reports. Once children commence ADHD medication, robust monitoring is required to detect partial or non-responses. The extent t... Read More about The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review.

Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades (2015)
Journal Article
Jung, J., Jackson, S. R., Nam, K., Hollis, C., & Jackson, G. M. (2015). Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades. Journal of Neuropsychology, 9(2), https://doi.org/10.1111/jnp.12044

Tourette syndrome (TS) is a neurodevelopmental disorder characterised by motor and vocal tics. Tics are repetitive and uncontrolled behaviours that have been associated with basal ganglia dysfunction. We investigated saccadic eye movements in a group... Read More about Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades.

Technological innovations in mental healthcare: harnessing the digital revolution (2015)
Journal Article
Hollis, C., Morriss, R., Martin, J., Amani, S., Cotton, R., Denis, M., & Lewis, S. (2015). Technological innovations in mental healthcare: harnessing the digital revolution. British Journal of Psychiatry, 206(4), https://doi.org/10.1192/bjp.bp.113.142612

Digital technology has the potential to transform mental healthcare by connecting patients, services and health data in new ways. Digital online and mobile applications can offer patients greater access to information and services and enhance clinica... Read More about Technological innovations in mental healthcare: harnessing the digital revolution.

Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial (2014)
Journal Article
Hall, C. L., Walker, G. M., Valentine, A. Z., Guo, B., Kaylor-Hughes, C., James, M., …Hollis, C. (2014). Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial. BMJ Open, 4(12), Article e006838. https://doi.org/10.1136/bmjopen-2014-006838

Introduction: The National Institute for Health and Care Excellence (NICE) guidelines for attention deficit/hyperactivity disorder (ADHD) state that young people need to have access to the best evidence-based care to improve outcome. The current ‘gol... Read More about Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial.

Services for young people with attention deficit/hyperactivity disorder transitioning from child to adult mental health services: a national survey of mental health trusts in England. (2014)
Journal Article
Hall, C. L., Newell, K., Taylor, J., Sayal, K., & Hollis, C. (2015). Services for young people with attention deficit/hyperactivity disorder transitioning from child to adult mental health services: a national survey of mental health trusts in England. Journal of Psychopharmacology, 29(1), https://doi.org/10.1177/0269881114550353

Transition from child to adult mental health services is considered to be a difficult process, particularly for individuals with neurodevelopmental disorders such as attention deficit/hyperactivity disorder (ADHD). This article presents results from... Read More about Services for young people with attention deficit/hyperactivity disorder transitioning from child to adult mental health services: a national survey of mental health trusts in England..

Innovations in practice: piloting electronic session-by-session monitoring in child and adolescent mental health : a preliminary study (2014)
Journal Article
Hall, C. L., Moldavsky, M., Taylor, J. A., Marriott, M., Goodman, R., Sayal, K., & Hollis, C. (2015). Innovations in practice: piloting electronic session-by-session monitoring in child and adolescent mental health : a preliminary study. Child and Adolescent Mental Health, 20(3), https://doi.org/10.1111/camh.12066

Background Recent UK initiatives have advocated the use of session-by-session outcome measurement in CAMHS. However, little is known about the feasibility of this approach. Method The PROMPT study (Patient Reported Outcome Monitoring Progres... Read More about Innovations in practice: piloting electronic session-by-session monitoring in child and adolescent mental health : a preliminary study.

A qualitative process evaluation of electronic session-by-session outcome measurement in child and adolescent mental health services (2014)
Journal Article
Hall, C. L., Taylor, J., Moldavsky, M., Marriott, M., Pass, S., Newell, K., …Hollis, C. (2014). A qualitative process evaluation of electronic session-by-session outcome measurement in child and adolescent mental health services. BMC Psychiatry, 14(113), https://doi.org/10.1186/1471-244X-14-113

Background Regular monitoring of patient progress is important to assess the clinical effectiveness of an intervention. Recently, initiatives within UK child and adolescent mental health services (CAMHS) have advocated the use of session-by-session... Read More about A qualitative process evaluation of electronic session-by-session outcome measurement in child and adolescent mental health services.

Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder (2013)
Journal Article
Groom, M. J., Liddle, E. B., Scerif, G., Liddle, P. F., Batty, M. J., Liotti, M., & Hollis, C. (2013). Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder. Journal of Child Psychology and Psychiatry, 54(8), https://doi.org/10.1111/jcpp.12069

Background Children with attention deficit hyperactivity disorder (ADHD) are characterised by developmentally inappropriate levels of hyperactivity, impulsivity and/or inattention and are particularly impaired when performing tasks that require a hi... Read More about Motivational incentives and methylphenidate enhance electrophysiological correlates of error monitoring in children with attention deficit/hyperactivity disorder.

Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate (2011)
Journal Article
Liddle, E. B., Hollis, C., Batty, M. J., Groom, M. J., Totman, J. J., Liotti, M., …Liddle, P. F. (2011). Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate. Journal of Child Psychology and Psychiatry, 52(7), https://doi.org/10.1111/j.1469-7610.2010.02333.x

Background: Deficits characteristic of Attention Deficit/Hyperactivity Disorder (ADHD), including poor attention and inhibitory control, are at least partially alleviated by factors that increase engagement of attention, suggesting a hypodopaminergic... Read More about Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate.

Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism (2002)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Hollis, C., & Groom, M. J. (2002). Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism. Journal of Attention Disorders, 26(3), 434-446. https://doi.org/10.1177/1087054720972793

Objective. We investigated autonomic arousal, attention and response conflict, in ADHD and autism. Method. Heart rate variability (HRV), and behavioural and electrophysiological indices of performance, were recorded during a task with low and hig... Read More about Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism.