Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis

Hollis, Chris; Pennant, Mary; Cuenca, Jose; Glazebrook, Cris; Kendall, Tim; Whittington, Craig; Stockton, Sarah; Larsson, Linn�a; Bunton, Penny; Dobson, Suzanne; Groom, Madeleine J.; Hedderly, Tammy; Heyman, Isobel; Jackson, Georgina M.; Jackson, Stephen; Murphy, Tara; Rickards, Hugh; Robertson, Mary; Stern, Jeremy

Abstract

Background: Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment.
Objective: To conduct a systematic review of the benefits and risks of pharmacological, behavioural and physical interventions for tics in children and young people with TS (part 1) and to explore the experience of treatment and services from the perspective of young people with TS and their parents (part 2).

Data Sources: For the systematic reviews (parts 1 and 2), mainstream bibliographic databases, The Cochrane Library, education, social care and grey literature databases were searched using subject headings and text words for tic* and Tourette* from database inception to January 2013.

Review/research methods: For part 1, randomised controlled trials and controlled before-and-after studies of pharmacological, behavioural or physical interventions in children or young people (aged

Citation

Hollis, C., Pennant, M., Cuenca, J., Glazebrook, C., Kendall, T., Whittington, C., …Stern, J. (2016). Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis. Health Technology Assessment, 20(4), 1-450. https://doi.org/10.3310/hta20040

• Journal Article Type: Article
• Acceptance Date: Sep 12, 2015
• Publication Date: Jan 1, 2016
• Deposit Date: Feb 23, 2016
• Publicly Available Date: Feb 23, 2016
• Journal: Health Technology Assessment
• Print ISSN: 1366-5278
• Electronic ISSN: 2046-4924
• Publisher: NIHR Journals Library
• Peer Reviewed: Peer Reviewed
• Volume: 20
• Issue: 4
• Pages: 1-450
• DOI: https://doi.org/10.3310/hta20040
• Public URL: https://nottingham-repository.worktribe.com/output/767814
• Publisher URL: http://www.journalslibrary.nihr.ac.uk/hta/volume-20/issue-4#abstract