All Outputs (559)

Physical activity for smoking cessation in pregnancy: randomised controlled trial (2015)
Journal Article
Ussher, M., Lewis, S., Aveyard, P., Manyonda, I., West, R., Lewis, B., …Coleman, T. (2015). Physical activity for smoking cessation in pregnancy: randomised controlled trial. BMJ, 350, Article h2145. https://doi.org/10.1136/bmj.h2145

Objective: To determine the effectiveness of a physical activity intervention for smoking cessation during pregnancy. Design: Parallel group, randomised controlled, multicentre trial. Setting: 13 hospitals in England, April 2009 to January 20... Read More about Physical activity for smoking cessation in pregnancy: randomised controlled trial.

The effect of emergency presentation on surgery and survival in lung cancer patients in England, 2006-2008 (2015)
Journal Article
Tataru, D., Jack, R. H., Lind, M. J., Møller, H., & Lüchtenborg, M. (2015). The effect of emergency presentation on surgery and survival in lung cancer patients in England, 2006-2008. Cancer Epidemiology, 39(4), 612-616. https://doi.org/10.1016/j.canep.2015.04.008

© 2015. A large proportion of lung cancer patients in England are diagnosed through an emergency route, which is associated with poorer outcomes. Here, we investigated the association between emergency presentation and the odds of undergoing surgical... Read More about The effect of emergency presentation on surgery and survival in lung cancer patients in England, 2006-2008.

A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32 (2015)
Journal Article
Hampshire, M., Park, S., Khan, N. F., KNOX, R., Malpass, A., Thomas, J., …Georgieva, Z. (2015). A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32. Medical Teacher, 37(7), 611-630. https://doi.org/10.3109/0142159X.2015.1032918

Background: General practice is increasingly used as a learning environment in undergraduate medical education in the UK. Aim: The aim of this project was to identify, summarise and synthesise research about undergraduate medical education in gene... Read More about A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32.

Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study (2015)
Journal Article
Baker, R., Orton, E., Tata, L. J., & Kendrick, D. (2015). Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study. Archives of Disease in Childhood, 100(5), https://doi.org/10.1136/archdischild-2013-305715

Aim: To investigate risk factors for first long-bone fractures in children up to 5 years old in order to provide evidence about which families could benefit from injury prevention interventions. Methods: Population-based matched nested case–control... Read More about Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study.

Nicotine replacement therapy in pregnancy and major congenital anomalies in offspring (2015)
Journal Article
Dhalwani, N. N., Szatkowski, L., Coleman, T., Fiaschi, L., & Tata, L. J. (2015). Nicotine replacement therapy in pregnancy and major congenital anomalies in offspring. Pediatrics, 135(5), https://doi.org/10.1542/peds.2014-2560

BACKGROUND AND OBJECTIVES: Nicotine replacement therapy (NRT) is now being used as a smoking cessation aid during pregnancy, although little is known about fetal safety. We assessed the relationship between early pregnancy exposure to NRT or smoking... Read More about Nicotine replacement therapy in pregnancy and major congenital anomalies in offspring.

Exploring the use of cost-benefit analysis to compare pharmaceutical treatments for menorrhagia (2015)
Journal Article
Sanghera, S., Frew, E., Gupta, J. K., Kai, J., & Roberts, T. E. (2015). Exploring the use of cost-benefit analysis to compare pharmaceutical treatments for menorrhagia. PharmacoEconomics, 33(9), https://doi.org/10.1007/s40273-015-0280-0

Background: The extra-welfarist theoretical framework tends to focus on health-related quality of life, whilst the welfarist framework captures a wider notion of well-being. EQ-5D and SF-6D are commonly used to value outcomes in chronic conditions wi... Read More about Exploring the use of cost-benefit analysis to compare pharmaceutical treatments for menorrhagia.

The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis (2015)
Journal Article
Achana, F. A., Sutton, A. J., Kendrick, D., Wynn, P., Young, B., Jones, D. R., …Cooper, N. J. (2015). The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis. PLoS ONE, 10(4), Article e0121122. https://doi.org/10.1371/journal.pone.0121122

Background: There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compare... Read More about The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis.

Do cravings predict smoking cessation in smokers calling a national quit line: secondary analyses from a randomised trial for the utility of ‘urges to smoke’ measures (2015)
Journal Article
Taggar, J. S., Lewis, S., Docherty, G., Bauld, L., McEwen, A., & Coleman, T. (in press). Do cravings predict smoking cessation in smokers calling a national quit line: secondary analyses from a randomised trial for the utility of ‘urges to smoke’ measures. Substance Abuse Treatment, Prevention, and Policy, 10(15), https://doi.org/10.1186/s13011-015-0011-8

BACKGROUND: Single-item urges to smoke measures have been contemplated as important measures of nicotine dependence This study aimed to prospectively determine the relationships between measures of craving to smoke and smoking cessation, and compare... Read More about Do cravings predict smoking cessation in smokers calling a national quit line: secondary analyses from a randomised trial for the utility of ‘urges to smoke’ measures.

Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline (2015)
Journal Article
Agboola, S. A., Coleman, T., McNeill, A., & Leonardi-Bee, J. (2015). Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline. Addiction, 110(7), 1182-1193. doi:10.1111/add.12941

Background and aims Varenicline increases the likelihood of long-term abstinence following a quit attempt. It has been suggested that 1) part of its benefit arises from ‘recruiting into abstinence’ smokers who are not able to stop on the target quit... Read More about Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline.

Does the timed up and go test predict future falls among British community-dwelling older people? Prospective cohort study nested within a randomised controlled trial (2015)
Journal Article
Kojima, G., Masud, T., Kendrick, D., Morris, R. W., Gawler, S., Treml, J., & Iliffe, S. (2015). Does the timed up and go test predict future falls among British community-dwelling older people? Prospective cohort study nested within a randomised controlled trial. BMC Geriatrics, 15(38), https://doi.org/10.1186/s12877-015-0039-7

Background Falling is common among older people. The Timed-Up-and-Go Test (TUG) is recommended as a screening tool for falls but its predictive value has been challenged. The objectives of this study were to examine the ability of TUG to predict f... Read More about Does the timed up and go test predict future falls among British community-dwelling older people? Prospective cohort study nested within a randomised controlled trial.

Preventing childhood scalds within the home: overview of systematic reviews and a systematic review of primary studies (2015)
Journal Article
Zou, K., Wynn, P. M., Miller, P., Hindmarch, P., Majsak-Newman, G., Young, B., …Kendrick, D. (2015). Preventing childhood scalds within the home: overview of systematic reviews and a systematic review of primary studies. Burns, 41(5), https://doi.org/10.1016/j.burns.2014.11.002

Objective: To synthesise and evaluate the evidence of the effectiveness of interventions to prevent scalds in children. Methods: An overview of systematic reviews (SR) and a SR of primary studies were performed evaluating interventions to prevent sc... Read More about Preventing childhood scalds within the home: overview of systematic reviews and a systematic review of primary studies.

The varying influence of socioeconomic deprivation on breast cancer screening uptake in London (2015)
Journal Article
Jack, R. H., Robson, T., & Davies, E. A. (2016). The varying influence of socioeconomic deprivation on breast cancer screening uptake in London. Journal of Public Health, 38(2), 330-334. https://doi.org/10.1093/pubmed/fdv038

Background We assessed the relationship between screening uptake and socioeconomic deprivation for London women aged 50-52 invited to their first routine screening appointment between 2006 and 2009. Methods We examined uptake for London overall and w... Read More about The varying influence of socioeconomic deprivation on breast cancer screening uptake in London.

Parental perceptions of barriers and facilitators to preventing child unintentional injuries within the home: a qualitative study (2015)
Journal Article
Ablewhite, J., Peel, I., McDaid, L., Hawkins, A., Goodenough, T., Deave, T., …Kendrick, D. (2015). Parental perceptions of barriers and facilitators to preventing child unintentional injuries within the home: a qualitative study. BMC Public Health, 15(280), https://doi.org/10.1186/s12889-015-1547-2

Background Childhood unintentional injury represents an important global health problem. Most of these injuries occur at home, and many are preventable. The main aim of this study was to identify key facilitators and barriers for parents in keepin... Read More about Parental perceptions of barriers and facilitators to preventing child unintentional injuries within the home: a qualitative study.

Comparison of coronary heart disease genetic assessment with conventional cardiovascular risk assessment in primary care: reflections on a feasibility study (2015)
Journal Article
Qureshi, N., Kai, J., Middlemass, J., Dhiman, P., Cross-Bardell, L., Acharya, J., …Standen, P. (2015). Comparison of coronary heart disease genetic assessment with conventional cardiovascular risk assessment in primary care: reflections on a feasibility study. Primary Health Care Research and Development, 16(6), 607-617. https://doi.org/10.1017/S1463423615000122

Aim: This study assesses the feasibility of collecting genetic samples and self-reported outcome measures after cardiovascular risk assessment, and presenting the genetic test results to participants. Background: Coronary heart disease (CHD) genetic... Read More about Comparison of coronary heart disease genetic assessment with conventional cardiovascular risk assessment in primary care: reflections on a feasibility study.

Maternal smoking and the risk of still birth: systematic review and meta-analysis (2015)
Journal Article
Marufu, T. C., Ahankari, A. S., Coleman, T., & Lewis, S. (in press). Maternal smoking and the risk of still birth: systematic review and meta-analysis. BMC Public Health, 15, Article 239. https://doi.org/10.1186/s12889-015-1552-5

BACKGROUND: Smoking in pregnancy is known to be associated with a range of adverse pregnancy outcomes, yet there is a high prevalence of smoking among pregnant women in many countries, and it remains a major public health concern. We have conducted a... Read More about Maternal smoking and the risk of still birth: systematic review and meta-analysis.

Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care?: study protocol for a randomised controlled trial (2015)
Journal Article
Downing, H. E., Carroll, F., Brookes, S. T., Hollinghurst, S., Timmins, D., Orton, E., …Hay, A. D. (2015). Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care?: study protocol for a randomised controlled trial. Trials, 16(1), Article 78. https://doi.org/10.1186/s13063-015-0569-5

Background: Acute lower respiratory tract infection (LRTI) is one of the most common conditions managed internationally and is costly to health services and patients. Despite good evidence that antibiotics are not effective for improving the symptom... Read More about Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care?: study protocol for a randomised controlled trial.

Recruitment and retention strategies and the examination of attrition bias in a randomised controlled trial in children’s centres serving families in disadvantaged areas of England (2015)
Journal Article
Hindmarch, P., Hawkins, A., McColl, E., Hayes, M., Majsak-Newman, G., Ablewhite, J., …Kendrick, D. (2015). Recruitment and retention strategies and the examination of attrition bias in a randomised controlled trial in children’s centres serving families in disadvantaged areas of England. Trials, 16(79), https://doi.org/10.1186/s13063-015-0578-4

Background Failure to retain participants in randomised controlled trials and longitudinal studies can cause significant methodological problems. We report the recruitment and retention strategies of a randomised controlled trial to promote fire-r... Read More about Recruitment and retention strategies and the examination of attrition bias in a randomised controlled trial in children’s centres serving families in disadvantaged areas of England.

Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study (2015)
Journal Article
Hippisley-Cox, J., & Coupland, C. (2015). Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study. BMJ Open, 5(3), Article e007825. https://doi.org/10.1136/bmjopen-2015-007825

Objective: To derive and validate a set of clinical risk prediction algorithm to estimate the 10-year risk of 11 common cancers. Design: Prospective open cohort study using routinely collected data from 753 QResearch general practices in England.... Read More about Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study.

Perspectives on enhancing physical activity and diet for health promotion among at-risk urban UK South Asian communities: a qualitative study (2015)
Journal Article
Cross-Bardell, L., George, T., Bhoday, M., Tuomainen, H., Qureshi, N., & Kai, J. (2015). Perspectives on enhancing physical activity and diet for health promotion among at-risk urban UK South Asian communities: a qualitative study. BMJ Open, 5(2), Article e007317. https://doi.org/10.1136/bmjopen-2014-007317

Objectives To explore perspectives on enhancing physical activity and diet among South Asians in urban deprived communities at high risk of chronic disease and to inform development of culturally appropriate health promotion intervention. Des... Read More about Perspectives on enhancing physical activity and diet for health promotion among at-risk urban UK South Asian communities: a qualitative study.

Antidepressant use and risk of suicide and attempted suicide or self harm in people aged 20 to 64: cohort study using a primary care database (2015)
Journal Article
Coupland, C., Hill, T., Morriss, R., Arthur, A., Moore, M., & Hippisley-Cox, J. (2015). Antidepressant use and risk of suicide and attempted suicide or self harm in people aged 20 to 64: cohort study using a primary care database. BMJ, 350(7996), Article h517. https://doi.org/10.1136/BMJ.h517

© BMJ Publishing Group Ltd 2015. Objective To assess the associations between different antidepressant treatments and the rates of suicide and attempted suicide or self harm in people with depression. Design Cohort study. Setting Patients registered... Read More about Antidepressant use and risk of suicide and attempted suicide or self harm in people aged 20 to 64: cohort study using a primary care database.