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Maternal smoking and the risk of still birth: systematic review and meta-analysis

Marufu, Takawira C.; Ahankari, Anand S.; Coleman, Tim; Lewis, Sarah

Authors

Takawira C. Marufu

Anand S. Ahankari

TIM COLEMAN tim.coleman@nottingham.ac.uk
Professor of Primary Care



Abstract

BACKGROUND: Smoking in pregnancy is known to be associated with a range of adverse pregnancy outcomes, yet there is a high prevalence of smoking among pregnant women in many countries, and it remains a major public health concern. We have conducted a systematic review and meta-analysis to provide contemporary estimates of the association between maternal smoking in pregnancy and the risk of stillbirth.

METHODS: We searched four databases namely MEDLINE, EMBASE, Psych Info and Web of Science for all relevant original studies published until 31(st) December 2012. We included observational studies that measured the association between maternal smoking during pregnancy and the risk of stillbirth.

RESULTS: 1766 studies were screened for title analysis, of which 34 papers (21 cohorts, 8 case controls and 5 cross sectional studies) met the inclusion criteria. In meta-analysis smoking during pregnancy was significantly associated with a 47% increase in the odds of stillbirth (OR 1.47, 95% CI 1.37, 1.57, p 

Journal Article Type Article
Journal BMC Public Health
Electronic ISSN 1471-2458
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 15
Article Number 239
APA6 Citation Marufu, T. C., Ahankari, A. S., Coleman, T., & Lewis, S. (in press). Maternal smoking and the risk of still birth: systematic review and meta-analysis. BMC Public Health, 15, https://doi.org/10.1186/s12889-015-1552-5
DOI https://doi.org/10.1186/s12889-015-1552-5
Publisher URL http://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-015-1552-5
Related Public URLs http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372174/
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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