Maternal smoking and the risk of still birth: systematic review and meta-analysis

Marufu, Takawira C.; Ahankari, Anand S.; Coleman, Tim; Lewis, Sarah

Abstract

BACKGROUND: Smoking in pregnancy is known to be associated with a range of adverse pregnancy outcomes, yet there is a high prevalence of smoking among pregnant women in many countries, and it remains a major public health concern. We have conducted a systematic review and meta-analysis to provide contemporary estimates of the association between maternal smoking in pregnancy and the risk of stillbirth.

METHODS: We searched four databases namely MEDLINE, EMBASE, Psych Info and Web of Science for all relevant original studies published until 31(st) December 2012. We included observational studies that measured the association between maternal smoking during pregnancy and the risk of stillbirth.

RESULTS: 1766 studies were screened for title analysis, of which 34 papers (21 cohorts, 8 case controls and 5 cross sectional studies) met the inclusion criteria. In meta-analysis smoking during pregnancy was significantly associated with a 47% increase in the odds of stillbirth (OR 1.47, 95% CI 1.37, 1.57, p?

Citation

Marufu, T. C., Ahankari, A. S., Coleman, T., & Lewis, S. (in press). Maternal smoking and the risk of still birth: systematic review and meta-analysis. BMC Public Health, 15, Article 239. https://doi.org/10.1186/s12889-015-1552-5

• Journal Article Type: Article
• Acceptance Date: Feb 16, 2015
• Online Publication Date: Mar 13, 2015
• Deposit Date: Aug 10, 2016
• Publicly Available Date: Aug 10, 2016
• Journal: BMC Public Health
• Electronic ISSN: 1471-2458
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 15
• Article Number: 239
• DOI: https://doi.org/10.1186/s12889-015-1552-5
• Public URL: https://nottingham-repository.worktribe.com/output/747706
• Publisher URL: http://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-015-1552-5
• Related Public URLs: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372174/