All Outputs (960)

Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data (2018)
Journal Article
Otete, H. E., Deleuran, T., Fleming, K. M., Card, T. R., Aithal, G. P., Jepsen, P., & West, J. (2018). Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data. Journal of Hepatology, 69(3), 697-704. https://doi.org/10.1016/j.jhep.2018.04.002

© 2018 European Association for the Study of the Liver Background & Aims: Cirrhosis, the prevalence of which is increasing, is a risk factor for osteoporosis and fractures. However, little is known of the actual risk of hip fractures in patients with... Read More about Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data.

Scaling the Peaks Research Protocol: understanding the barriers and drivers to providing and using dementia-friendly community services in rural areas—a mixed methods study (2018)
Journal Article
Marshall, F., Basiri, A., Riley, M., Dening, T., Gladman, J. R., Griffiths, A., & Lewis, S. (2018). Scaling the Peaks Research Protocol: understanding the barriers and drivers to providing and using dementia-friendly community services in rural areas—a mixed methods study. BMJ Open, 8(4), 1-10. https://doi.org/10.1136/bmjopen-2017-020374

Introduction: Scaling the Peaks is a cross-disciplinary research study which draws on medical ethnography, human geography and Geospatial Information Science (GIS) to address the issues surrounding the design and delivery of dementia friendly service... Read More about Scaling the Peaks Research Protocol: understanding the barriers and drivers to providing and using dementia-friendly community services in rural areas—a mixed methods study.

What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab? (2018)
Journal Article
Card, T. R., Xu, J., Liang, H., & Bhayat, F. (2018). What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab?. Inflammatory Bowel Diseases, 24(5), https://doi.org/10.1093/ibd/izx097

Background: Progressive multifocal leukoencephalopathy is a serious condition linked to certain diseases and immunosuppressant therapies, including the α4 integrin antagonist natalizumab. No cases have been reported to date with vedolizumab, a select... Read More about What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab?.

Cost-effectiveness of interventions to control cardiovascular diseases and diabetes mellitus in South Asia: a systematic review (2018)
Journal Article
Singh, K., Chandrasekaran, A., Bhaumik, S., Chattopadhyay, K., Gamage, A. U., Silva, P. D., …Tandon, N. (2018). Cost-effectiveness of interventions to control cardiovascular diseases and diabetes mellitus in South Asia: a systematic review. BMJ Open, 8(4), Article e017809. https://doi.org/10.1136/bmjopen-2017-017809

OBJECTIVES: More than 80% of cardiovascular diseases (CVD) and diabetes mellitus (DM) burden now lies in low and middle-income countries. Hence, there is an urgent need to identify and implement the most cost-effective interventions, particularly in... Read More about Cost-effectiveness of interventions to control cardiovascular diseases and diabetes mellitus in South Asia: a systematic review.

Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation (2018)
Journal Article
Prasad, V., West, J., Kendrick, D., & Sayal, K. (2019). Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation. Archives of Disease in Childhood, 104(8), 802-805. https://doi.org/10.1136/archdischild-2017-314470

Background: In England, there is a discrepancy between the prevalence of Attention-deficit/hyperactivity disorder (ADHD) ascertained from medical records and community surveys. There is also a lack of data on variation in recorded prevalence by depri... Read More about Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation.

Glycaemic control in type 2 diabetes patients and its predictors: a retrospective database study at a tertiary care diabetes centre in Ningbo, China (2018)
Journal Article
Li, J., Chattopadhyay, K., Xu, M., Chen, Y., Hu, F., Chu, J., & Li, L. (in press). Glycaemic control in type 2 diabetes patients and its predictors: a retrospective database study at a tertiary care diabetes centre in Ningbo, China. BMJ Open, 8(3), Article e019697. https://doi.org/10.1136/bmjopen-2017-019697

Objectives: The objectives of the study were to assess glycaemic control in patients with type 2 diabetes (T2DM) at a tertiary care diabetes centre in Ningbo, China and to determine factors that independently predict their glycaemic control. Desig... Read More about Glycaemic control in type 2 diabetes patients and its predictors: a retrospective database study at a tertiary care diabetes centre in Ningbo, China.

A qualitative study of community perception and acceptance of biological larviciding for malaria mosquito control in rural Burkina Faso (2018)
Journal Article
Dambach, P., Mendes Jorge, M., Traoré, I., Phalkey, R., Sawadogo, H., Zabré, P., …Beiersmann, C. (2018). A qualitative study of community perception and acceptance of biological larviciding for malaria mosquito control in rural Burkina Faso. BMC Public Health, 18, Article 399. https://doi.org/10.1186/s12889-018-5299-7

Background: Vector and malaria parasite’s rising resistance against pyrethroid-impregnated bed nets and antimalarial drugs highlight the need for additional control measures. Larviciding against malaria vectors is experiencing a renaissance with the... Read More about A qualitative study of community perception and acceptance of biological larviciding for malaria mosquito control in rural Burkina Faso.

Whole genome sequencing in the investigation of recurrent invasive Group A streptococcus outbreaks in a maternity unit (2018)
Journal Article
Dickinson, H., Reacher, M., Nazareth, B., Eagle, H., Fowler, D., Underwood, A., …Puleston, R. (2019). Whole genome sequencing in the investigation of recurrent invasive Group A streptococcus outbreaks in a maternity unit. Journal of Hospital Infection, 101(3), 320-326. https://doi.org/10.1016/j.jhin.2018.03.018

Background: The clinical manifestations of Group A streptococcus (GAS) – (Streptococcus pyogenes) are diverse, ranging from asymptomatic colonisation to devastating invasive disease. Maternity related clusters of invasive Group A streptococcus (iGAS... Read More about Whole genome sequencing in the investigation of recurrent invasive Group A streptococcus outbreaks in a maternity unit.

Risk of fall in patients with COPD (2018)
Journal Article
Hakamy, A., Bolton, C. E., Gibson, J. E., & McKeever, T. M. (2018). Risk of fall in patients with COPD. Thorax, 73(11), 1079-1080. https://doi.org/10.1136/thoraxjnl-2017-211008

A matched cohort study was conducted to determine the incidence of falls in patients following a diagnosis of COPD using a UK primary care database. 44 400 patients with COPD and 175?545 non-COPD subjects were identified. The incidence rate of fall p... Read More about Risk of fall in patients with COPD.

Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings (2018)
Journal Article
Qureshi, N., Weng, S. F., Tranter, J. A., Da Silva, M. L., Kai, J., & Leonardi-Bee, J. (2018). Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings. Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012985

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The purpose of this review is to assess the effectiveness of interventions to systematically improve identification of FH in non-specialist settings compared t... Read More about Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings.

Prevalence and factors associated with exposure to second-hand smoke (SHS) among young people: a cross-sectional study from The Gambia (2018)
Journal Article
Jallow, I. K., Britton, J., & Langley, T. (2018). Prevalence and factors associated with exposure to second-hand smoke (SHS) among young people: a cross-sectional study from The Gambia. BMJ Open, 8(3), 1-8. https://doi.org/10.1136/bmjopen-2017-019524

Background: Annually 600,000 deaths are attributed to exposure of non-smokers to second-hand smoke (SHS). These include 165,000 among children, about 60% of which occur in Africa and South-East Asia. In 2011 only four countries in the African region... Read More about Prevalence and factors associated with exposure to second-hand smoke (SHS) among young people: a cross-sectional study from The Gambia.

Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol) (2018)
Journal Article
Doleman, B., Leonardi-Bee, J., Heinink, T. P., Lund, J., & Williams, J. P. (2018). Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol). Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012978

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate in adult participants undergoing all types of surgery, the effects of pre-emptive and preventive non-steroidal anti-inflammatory drugs (NSAIDs) com... Read More about Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol).

Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations (2018)
Journal Article
McKeever, T., Mortimer, K., Wilson, A., Walker, S., Brightling, C., Skeggs, A., …Harrison, T. (2018). Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations. New England Journal of Medicine, 378(10), 902-910. https://doi.org/10.1056/NEJMoa1714257

Copyright © 2018 Massachusetts Medical Society. BACKGROUND Asthma exacerbations are frightening for patients and are occasionally fatal. We tested the concept that a plan for patients to manage their asthma (self-management plan), which included a te... Read More about Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations.

Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2018)
Journal Article
Garcia-Larsen, V., Ierodiakonou, D., Jarrold, K., Cunha, S., Chivinge, J., Robinson, Z., …Boyle, R. J. (2018). Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis. PLoS Medicine, 15(2), Article e1002507. https://doi.org/10.1371/journal.pmed.1002507

Background: There is uncertainty about the influence of diet during pregnancy and infancy on a child’s immune development. We assessed whether variations in maternal or infant diet can influence risk of allergic or autoimmune disease. Methods and fi... Read More about Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis.

A survey of tobacco dependence treatment guidelines content in 61 countries (2018)
Journal Article
Nilan, K., McNeill, A., Murray, R. L., McKeever, T. M., & Raw, M. (2018). A survey of tobacco dependence treatment guidelines content in 61 countries. Addiction, 113(8), 1499-1506. https://doi.org/10.1111/add.14204

Aims: To assess tobacco dependence treatment guidelines content in accordance with Article 14 of the World Health Organisation (WHO) Framework Convention on Tobacco Control (FCTC) and its guidelines, and association between content and country income... Read More about A survey of tobacco dependence treatment guidelines content in 61 countries.

Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink (2018)
Journal Article
Pearce, F. A., Lanyon, P. C., Watts, R. A., Grainge, M. J., Abhishek, A., & Hubbard, R. B. (2018). Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink. Rheumatology, 57(6), 1002-1010. https://doi.org/10.1093/rheumatology/kex512

Objectives: We aimed to provide insights into the aetiology of granulomatosis with polyangiitis (GPA), by conducting a large case–control study using a general population-based, prospectively collected database of healthcare records. Methods: We... Read More about Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink.

Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink (2018)
Journal Article
Abhishek, A., Nakafero, G., Kuo, C., Mallen, C., Zhang, W., Grainge, M. J., & Doherty, M. (2018). Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink. Rheumatology, 57(6), 977–981. https://doi.org/10.1093/rheumatology/key013

Objectives: To examine temporal trends in all-cause and cause-specific mortality in RA. Methods: Data from the Clinical Practice Research Datalink (CPRD) were used. Incident RA cases and four age, sex and general practice matched controls were id... Read More about Rheumatoid arthritis and excess mortality: down but not out: a primary care cohort study using data from Clinical Practice Research Datalink.

A Cross-Sectional Study of the Impact of Standardized Tobacco Packaging Legislation on University Students (2018)
Journal Article
Poundall, T., Bogdanovica, I., & Langley, T. (2018). A Cross-Sectional Study of the Impact of Standardized Tobacco Packaging Legislation on University Students. Journal of Child and Adolescent Substance Abuse, 27(3), 165-173. https://doi.org/10.1080/1067828X.2018.1431992

Background: European Union and national legislation implemented from May 2016 mean that from May 2017 all tobacco products in the United Kingdom must be sold in standardized packs without external branding and with prominent graphic health warnings.... Read More about A Cross-Sectional Study of the Impact of Standardized Tobacco Packaging Legislation on University Students.

Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics (2018)
Journal Article
Sanderson, M., Chikhani, M., Blyth, E., Wood, S., Moppett, I. K., McKeever, T., & Simmonds, M. J. (2018). Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics. Journal of the Intensive Care Society, 19(4), 299-304. https://doi.org/10.1177/1751143718758975

Background Sepsis represents a significant public health burden, costing the NHS £2.5 billion annually, with 35% mortality in 2006. The aim of this exploratory study was to investigate risk factors predictive of 30-day mortality amongst patients w... Read More about Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics.

13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups (2018)
Journal Article
Daniel, P., Rodrigo, C., Bewick, T., Sheppard, C., Greenwood, S., McKeever, T. M., …Lim, W. S. (2018). 13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups. Vaccine, 36(12), 1614-1620. https://doi.org/10.1016/j.vaccine.2018.02.005

There is debate regarding the value of vaccinating adults with the 13-valent pneumococcal conjugate vaccine (PCV-13). This analysis was conducted to investigate the risk of PCV-13 serotype community acquired pneumonia (CAP) in hospitalised adults wit... Read More about 13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups.