Skip to main content

Research Repository

Advanced Search

All Outputs (1122)

Robust Data-Driven Auditory Profiling Towards Precision Audiology (2020)
Journal Article
Sanchez-Lopez, R., Fereczkowski, M., Neher, T., Santurette, S., & Dau, T. (2020). Robust Data-Driven Auditory Profiling Towards Precision Audiology. Trends in Hearing, 24, https://doi.org/10.1177/2331216520973539

The sources and consequences of a sensorineural hearing loss are diverse. While several approaches have aimed at disentangling the physiological and perceptual consequences of different etiologies, hearing deficit characterization and rehabilitation... Read More about Robust Data-Driven Auditory Profiling Towards Precision Audiology.

Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups (2020)
Journal Article
Tarlinton, R., Wang, B., Morandi, E., Gran, B., Khaibullin, T., Martynova, E., …Khaiboullina, S. (2020). Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups. Frontiers in Pharmacology, 10, Article 1645. https://doi.org/10.3389/fphar.2019.01645

Copyright © 2020 Tarlinton, Wang, Morandi, Gran, Khaiboullin, Martynova, Rizvanov and Khaiboullina. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction... Read More about Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups.

Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group (2020)
Journal Article
Wilson, A., on behalf of the ESO Health Economics Working group, Cadilhac, D. A., Kim, J., Berge, E., Patel, A., …Ranta, A. (2020). Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group. European Stroke Journal, 5(2), 184-192. https://doi.org/10.1177/2396987319897466

Abstract Introduction: Approaches to economic evaluations of stroke therapies are varied and inconsistently described. An objective of the European Stroke Organisation (ESO) Health Economics Working Group is to standardise and improve the economic ev... Read More about Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group.

Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid (2020)
Journal Article
Law, Z. K., England, T. J., Mistri, A. K., Woodhouse, L. J., Cala, L., Dineen, R., …TICH-2 investigators. (2020). Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid. European Stroke Journal, 5(2), 123-129. https://doi.org/10.1177/2396987320901391

Introduction: Seizures are common after intracerebral haemorrhage. Tranexamic acid increases the risk of seizures in non-intracerebral haemorrhage population but its effect on post-intracerebral haemorrhage seizures is unknown. We explored the risk f... Read More about Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid.

Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke (2020)
Journal Article
Appleton, J. P., Krishnan, K., & Bath, P. M. (2020). Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke. Expert Opinion on Drug Delivery, 17(3), 297-303. https://doi.org/10.1080/17425247.2020.1716727

© 2020 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Glyceryl trinitrate (GTN), a nitric oxide donor, is a candidate treatment for the management of acute stroke with hemodynamic and potential reperfusion and neuroprotective... Read More about Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke.

Elevated plasminogen activators are associated with hematoma progression in spontaneous intracerebral hemorrhage (2020)
Journal Article
Law, Z. K., Desborough, M., Rakkar, K., Bath, P. M., Bayraktutan, U., & Sprigg, N. (2020). Elevated plasminogen activators are associated with hematoma progression in spontaneous intracerebral hemorrhage. Brain Hemorrhages, 1(1), 75-79. https://doi.org/10.1016/j.hest.2019.12.001

Endogenous fibrinolysis might lead to hematoma progression in spontaneous intracerebral hemorrhage (ICH). We studied plasma biomarkers of fibrinolysis and hemostasis in twenty-two patients with ICH and nine healthy controls (HC) in a single-center st... Read More about Elevated plasminogen activators are associated with hematoma progression in spontaneous intracerebral hemorrhage.

Accuracy and clinical utility of comprehensive dysphagia screening assessments in acute stroke: A systematic review and meta?analysis (2020)
Journal Article
Benfield, J. K., Everton, L. F., Bath, P. M., & England, T. J. (2020). Accuracy and clinical utility of comprehensive dysphagia screening assessments in acute stroke: A systematic review and meta?analysis. Journal of Clinical Nursing, 29(9-10), 1527-1538. https://doi.org/10.1111/jocn.15192

Introduction Nurses and other nonspecialists in dysphagia are often trained to screen swallowing poststroke. There are many basic tools that test water only, they are usually conservative, and patients that fail the test remain nil by mouth until... Read More about Accuracy and clinical utility of comprehensive dysphagia screening assessments in acute stroke: A systematic review and meta?analysis.

Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe (2020)
Journal Article
Cima, R. F., Kikidis, D., Mazurek, B., Haider, H., Cederroth, C. R., Norena, A., …Hoare, D. J. (2020). Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe. BMJ Open, 10(1), Article e029346. https://doi.org/10.1136/bmjopen-2019-029346

Tinnitus remains a scientific and clinical problem whereby, in spite of increasing knowledge on effective treatment and management for tinnitus, very little impact on clinical practice has been observed. There is evidence that prolonged, obscure and... Read More about Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe.

High Xe density, high photon flux, stopped-flow spin-exchange optical pumping: Simulations versus experiments (2020)
Journal Article
Skinner, J. G., Ranta, K., Whiting, N., Coffey, A. M., Nikolaou, P., Rosen, M. S., …Goodson, B. M. (2020). High Xe density, high photon flux, stopped-flow spin-exchange optical pumping: Simulations versus experiments. Journal of Magnetic Resonance, 312, Article 106686. https://doi.org/10.1016/j.jmr.2020.106686

© 2020 Elsevier Inc. Spin-exchange optical pumping (SEOP) can enhance the NMR sensitivity of noble gases by up to five orders of magnitude at Tesla-strength magnetic fields. SEOP-generated hyperpolarised (HP) 129Xe is a promising contrast agent for l... Read More about High Xe density, high photon flux, stopped-flow spin-exchange optical pumping: Simulations versus experiments.

Group cognitive rehabilitation to reduce the psychological impact of multiple sclerosis on quality of life: the CRAMMS RCT (2020)
Journal Article
Lincoln, N. B., Bradshaw, L. E., Constantinescu, C. S., Day, F., Drummond, A. E., Fitzsimmons, D., …CRAMMS Trial Collaborative Group. (2020). Group cognitive rehabilitation to reduce the psychological impact of multiple sclerosis on quality of life: the CRAMMS RCT. Health Technology Assessment, 24(4), 1-182. https://doi.org/10.3310/hta24040

Abstract Background People with multiple sclerosis have problems with memory and attention. The effectiveness of cognitive rehabilitation has not been established. Objectives The objectives were to assess the clinical effectiveness and cost-eff... Read More about Group cognitive rehabilitation to reduce the psychological impact of multiple sclerosis on quality of life: the CRAMMS RCT.

Radiological evaluation of newly diagnosed non-brainstem pediatric high-grade glioma in the HERBY phase II trial (2020)
Journal Article
Rodriguez, D., Jones, C., Varlet, P., Mackay, A., Warren, D., Warmuth-Metz, M., …Jaspan, T. (2020). Radiological evaluation of newly diagnosed non-brainstem pediatric high-grade glioma in the HERBY phase II trial. Clinical Cancer Research, 26(8), 1856-1865. https://doi.org/10.1158/1078-0432.ccr-19-3154

Purpose: The HERBY trial evaluated the benefit of the addition of the antiangiogenic agent Bevacizumab (BEV) to radiotherapy/temozolomide (RT/TMZ) in pediatric patients with newly diagnosed non-brainstem high-grade glioma (HGG). The work presented he... Read More about Radiological evaluation of newly diagnosed non-brainstem pediatric high-grade glioma in the HERBY phase II trial.

Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study (2020)
Journal Article
Othman, O., Rakkar, K., Sprigg, N., Bath, P., & Bayraktutan, U. (2020). Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study. Neural Regeneration Research, 15(7), 1300-1307. https://doi.org/10.4103/1673-5374.269028

Ischemic stroke is a devastating, life altering event which can severely reduce patient quality of life. Despite years of research there have been minimal therapeutic advances. Endothelial progenitor cells (EPCs), stem cells involved in both vasculog... Read More about Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study.

Image-guided neural activity manipulation with a paramagnetic drug (2020)
Journal Article
Bricault, S., Barandov, A., Harvey, P., DeTienne, E., Hai, A., & Jasanoff, A. (2020). Image-guided neural activity manipulation with a paramagnetic drug. Nature Communications, 11(1), Article 136. https://doi.org/10.1038/s41467-019-13933-5

© 2020, The Author(s). Targeted manipulations of neural activity are essential approaches in neuroscience and neurology, but monitoring such procedures in the living brain remains a significant challenge. Here we introduce a paramagnetic analog of th... Read More about Image-guided neural activity manipulation with a paramagnetic drug.

TRY plant trait database – enhanced coverage and open access (2019)
Journal Article
Kattge, J., Bönisch, G., Díaz, S., Lavorel, S., Prentice, I. C., Leadley, P., …The Nutrient Network. (2020). TRY plant trait database – enhanced coverage and open access. Global Change Biology, 26(1), 119-188. https://doi.org/10.1111/gcb.14904

© 2019 The Authors. Global Change Biology published by John Wiley & Sons Ltd Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, af... Read More about TRY plant trait database – enhanced coverage and open access.

Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review (2019)
Journal Article
Oates, L. L., Moghaddam, N., Evangelou, N., & das Nair, R. (2020). Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review. Clinical Rehabilitation, 34(3), 310-319. https://doi.org/10.1177/0269215519896404

© The Author(s) 2019. Objective: To evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations. Data sources: PsycINFO, MEDLINE, CINAHL, AME... Read More about Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review.

Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy (2019)
Journal Article
Baguley, D. M., & Prayuenyong, P. (2020). Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy. Cancer Chemotherapy and Pharmacology, 85(2), 245-250. https://doi.org/10.1007/s00280-019-04012-z

© 2019, The Author(s). Introduction: Ototoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors. Discussion: In this article, we highlight important aspects of the evaluat... Read More about Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy.

Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage (2019)
Journal Article
Bayraktutan, U., Abdulkadir, R., Alwjwaj, M., Othman, O., & Rakkar, K. (2020). Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage. Neural Regeneration Research, 15(6), 1071-1078. https://doi.org/10.4103/1673-5374.269029

Breakdown of blood-brain barrier, formed mainly by brain microvascular endothelial cells (BMECs), represents the major cause of mortality during early phases of ischemic strokes. Hence, discovery of novel agents that can effectively replace dead or d... Read More about Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage.

Tinnitus, hearing loss and inflammatory processes in an older Portuguese population (2019)
Journal Article
Haider, H. F., Ribeiro, S. F., Martins, C., Ribeiro, D., Trigueiros, N., Szczepek, A. J., …Borrego, L. (2019). Tinnitus, hearing loss and inflammatory processes in an older Portuguese population. International Journal of Audiology, 59(5), 323-332. https://doi.org/10.1080/14992027.2019.1698775

Objective: Tinnitus is associated with various conditions such as presbycusis, infectious, autoimmune and many other diseases. Our study aims to identify an association between inflammatory markers and the presence of tinnitus or hearing loss (HL).... Read More about Tinnitus, hearing loss and inflammatory processes in an older Portuguese population.

How do patients spend their time in stroke rehabilitation units in England? The REVIHR study (2019)
Journal Article
Chouliara, N., Fisher, R., Crosbie, B., Guo, B., Sprigg, N., & Walker, M. (2021). How do patients spend their time in stroke rehabilitation units in England? The REVIHR study. Disability and Rehabilitation, 43(16), 2312-2319. https://doi.org/10.1080/09638288.2019.1697764

Aim: To examine how patients spend their time in stroke rehabilitation units in England. Methods: We recruited 144 patients within a month after stroke from four stroke rehabilitation units and observed their activity type, interactions and locati... Read More about How do patients spend their time in stroke rehabilitation units in England? The REVIHR study.