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All Outputs (149)

Sound therapy (using amplification devices and/or sound generators) for tinnitus in adults (Protocol) (2018)
Journal Article
Sereda, M., Xia, J., El Refaie, A., Hall, D. A., & Hoare, D. (2018). Sound therapy (using amplification devices and/or sound generators) for tinnitus in adults (Protocol). Cochrane Database of Systematic Reviews, 2018(8), Article CD013094. https://doi.org/10.1002/14651858.CD013094

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of sound therapy (using amplification devices and/or sound generators) for tinnitus in adults.

Validity and reliability of an objective structured assessment tool for performance of ultrasound-guided regional anaesthesia (2018)
Journal Article
Shafqat, A., Rafi, M., Thanawala, V., Bedforth, N. M., Hardman, J., & McCahon, R. A. (2018). Validity and reliability of an objective structured assessment tool for performance of ultrasound-guided regional anaesthesia. British Journal of Anaesthesia, 121(4), 867-875. https://doi.org/10.1016/j.bja.2018.06.014

Background: We aimed to examine the validity and reliability of previously developed criterion-referenced assessment checklist (AC) and global rating scale (GRS) to assess performance in ultrasound-guided regional anaesthesia (UGRA). Methods: Twenty... Read More about Validity and reliability of an objective structured assessment tool for performance of ultrasound-guided regional anaesthesia.

Assessment of diaphragmatic thickness by ultrasonography in Duchenne muscular dystrophy (DMD) patients (2018)
Journal Article
Laviola, M., Priori, R., D’Angelo, M. G., & Aliverti, A. (2018). Assessment of diaphragmatic thickness by ultrasonography in Duchenne muscular dystrophy (DMD) patients. PLoS ONE, 13(7), 1-13. https://doi.org/10.1371/journal.pone.0200582

Introduction In Duchenne muscular dystrophy (DMD) the assessment of diaphragmatic function is crucial because respiratory muscle weakness can cause respiratory failure. We aimed to noninvasively assess diaphragmatic function in DMD by measuring diap... Read More about Assessment of diaphragmatic thickness by ultrasonography in Duchenne muscular dystrophy (DMD) patients.

Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling (2018)
Journal Article
Mohammed, I., Ross, A. R., Britton, J. O., Said, D. G., & Dua, H. S. (2018). Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling. American Journal of Ophthalmology, 194, 16-25. https://doi.org/10.1016/j.ajo.2018.07.001

Purpose Descemet membrane endothelial keratoplasty (DMEK) and pre-Descemet endothelial keratoplasty (PDEK) tissues always scroll with the endothelial cells (EC) outside. We designed a study to understand the reason for this behavior. Design... Read More about Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling.

Do individual versus illness belief schema differ in the prediction of post-stroke recovery? (2018)
Journal Article
Aujla, N., Walker, M., Sprigg, N., & Vedhara, K. (2020). Do individual versus illness belief schema differ in the prediction of post-stroke recovery?. Journal of Health Psychology, 25(13-14), 2118-2128. https://doi.org/10.1177/1359105318785446

This longitudinal observational study examined how individual versus illness belief schema compare as predictors of post-stroke recovery. Forty-two stroke survivors (mean age=66.9 years/range=29-96 years; 68% male), were involved. The primary outcome... Read More about Do individual versus illness belief schema differ in the prediction of post-stroke recovery?.

Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage (2018)
Journal Article
Foster, R. J., Damion, R. A., Ries, M. E., Smye, S. W., McGonagle, D. G., Binks, D. A., & Radjenovic, A. (2018). Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage. Royal Society Open Science, 5(7), https://doi.org/10.1098/rsos.180221

Samples of human and bovine cartilage have been examined using magnetic resonance imaging to determine the proton nuclearmagnetic resonance spin-lattice relaxation time, T1, as a function of depth within the cartilage tissue. T1 was measured at five... Read More about Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage.

Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score (2018)
Journal Article
Sinha, R., Correia, R., Gardner, D., Grau-Roma, L., de Brot, S., Hardman, J., …Norris, A. (2018). Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score. Laryngoscope Investigative Otolaryngology, 3(4), 257-262. https://doi.org/10.1002/lio2.168

Objectives: Postintubation laryngotracheal injury is common. Assessment of histopathological changes currently requires animal models. We set about developing a viable, resource effective animal model to study these effects and to develop a detailed... Read More about Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score.

A comparison of two different software packages for the analysis of body composition using computed tomography images (2018)
Journal Article
Rollins, K. E., Awwad, A., MacDonald, I. A., & Lobo, D. N. (2019). A comparison of two different software packages for the analysis of body composition using computed tomography images. Nutrition, 57, 92-96. https://doi.org/10.1016/j.nut.2018.06.003

Objectives: Body composition analysis from computed tomography (CT) imaging has become widespread. However, the methodology used is far from established. Two main software packages are in common usage for body composition analysis, with results used... Read More about A comparison of two different software packages for the analysis of body composition using computed tomography images.

Retinal basal laminar deposits in complement fH/fP mouse model of dense deposit disease (2018)
Journal Article
Song, D., Mohammed, I., Bhuyan, R., Miwa, T., Williams, A. L., Gullipalli, D., …Song, W. (2018). Retinal basal laminar deposits in complement fH/fP mouse model of dense deposit disease. Investigative Ophthalmology & Visual Science, 59(8), 3405-3415. https://doi.org/10.1167/iovs.18-24133

Purpose: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM). C... Read More about Retinal basal laminar deposits in complement fH/fP mouse model of dense deposit disease.

Development of the Social Participation Restrictions Questionnaire (SPaRQ) through consultation with adults with hearing loss, researchers, and clinicians: a content evaluation study (2018)
Journal Article
Heffernan, E., Coulson, N. S., & Ferguson, M. (in press). Development of the Social Participation Restrictions Questionnaire (SPaRQ) through consultation with adults with hearing loss, researchers, and clinicians: a content evaluation study. International Journal of Audiology, https://doi.org/10.1080/14992027.2018.1483585

Objective - This research aimed to evaluate the content of the Social Participation Restrictions Questionnaire (SPaRQ) in terms of its relevance, clarity, comprehensiveness, acceptability to adults with hearing loss, and responsiveness. Design -... Read More about Development of the Social Participation Restrictions Questionnaire (SPaRQ) through consultation with adults with hearing loss, researchers, and clinicians: a content evaluation study.

An inhaled sGC modulator can lower PH in COPD patients without deteriorating oxygenation (2018)
Journal Article
Saffaran, S., Wang, W., Das, A., Schmitt, W., Becker-Pelster, E., Hardman, J. G., …Bates, D. G. (2018). An inhaled sGC modulator can lower PH in COPD patients without deteriorating oxygenation. CPT: Pharmacometrics and Systems Pharmacology, 7(8), 491-498. https://doi.org/10.1002/psp4.12308

This study uses a highly fidelity computational simulator of pulmonary physiology to evaluate the impact of a soluble guanylate cyclase (sGC) modulator on gas exchange in patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypert... Read More about An inhaled sGC modulator can lower PH in COPD patients without deteriorating oxygenation.

Sensing Uranyl(VI) Ions by Coordination and Energy Transfer to a Luminescent Europium(III) Complex (2018)
Journal Article
Harvey, P., Nonat, A., Platas-Iglesias, C., Natrajan, L. S., & Charbonnière, L. J. (2018). Sensing Uranyl(VI) Ions by Coordination and Energy Transfer to a Luminescent Europium(III) Complex. Angewandte Chemie, 130(31), 10069-10072. https://doi.org/10.1002/ange.201805316

The release of uranyl(VI) is a hazardous environmental issue, with limited ways to monitor accumulation in situ. Here, we present a method for the detection of uranyl(VI) ions through the utilization of a unique fluorescence energy transfer process t... Read More about Sensing Uranyl(VI) Ions by Coordination and Energy Transfer to a Luminescent Europium(III) Complex.

Evaluating a stroke-specific version of the Illness Perception Questionnaire–Revised, using the Think-Aloud method (2018)
Journal Article
Aujla, N., Vedhara, K., Walker, M., & Sprigg, N. (2020). Evaluating a stroke-specific version of the Illness Perception Questionnaire–Revised, using the Think-Aloud method. Journal of Health Psychology, 25(12), 1989-2005. https://doi.org/10.1177/1359105318781942

The main purpose was to evaluate, using the Think-Aloud method, a version of the Illness Perception Questionnaire-Revised (IPQ-R) for stroke survivors (the Stroke IPQ-R). Six stroke survivors (mean age=58.8 years, range=31 to 78 years, SD=18.9 years)... Read More about Evaluating a stroke-specific version of the Illness Perception Questionnaire–Revised, using the Think-Aloud method.

A cross-sectional questionnaire study of tinnitus awareness and impact in a population of adult cochlear implant users (2018)
Journal Article
Gomersall, P. A., Baguley, D., & Carlyon, R. P. (2019). A cross-sectional questionnaire study of tinnitus awareness and impact in a population of adult cochlear implant users. Ear and Hearing, 40(1), 135-142. https://doi.org/10.1097/AUD.0000000000000601

Objectives: The primary aim was to identify the proportion of individuals within the adult cochlear implant population who are aware of tinnitus and those who report a negative impact from this perception, using a bespoke questionnaire designed to li... Read More about A cross-sectional questionnaire study of tinnitus awareness and impact in a population of adult cochlear implant users.

Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques (2018)
Journal Article
Eithne, H., David, M., Johanna, B., & Melanie, F. (in press). Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques. Ear and Hearing, https://doi.org/10.1097/AUD.0000000000000618

Objectives: The primary aim of this research was to refine and validate the Social Participation Restrictions Questionnaire (SPaRQ). The SPaRQ is a hearing-specific, patient-reported outcome measure that was originally developed through consultation... Read More about Refinement and validation of the Social Participation Restrictions Questionnaire: an application of Rasch analysis and traditional psychometric analysis techniques.

Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial (2018)
Journal Article
Ovesen, C., Jakobsen, J. C., Gluud, C., Steiner, T., Law, Z., Flaherty, K., …Christensen, H. (2018). Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial. BMC Research Notes, 11, Article 379. https://doi.org/10.1186/s13104-018-3481-8

Objective We present the statistical analysis plan of a prespecified Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage (TICH)-2 sub-study aiming to investigate, if tranexamic acid has a different effect in intracerebral haemorrhage... Read More about Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial.

Pupil light reflex evoked by light-emitting diode and computer screen: methodology and association with need for recovery in daily life (2018)
Journal Article
Wang, Y., Zekveld, A. A., Wendt, D., Lunner, T., Naylor, G., & Kramer, S. E. (2018). Pupil light reflex evoked by light-emitting diode and computer screen: methodology and association with need for recovery in daily life. PLoS ONE, 13(6), Article e0197739. https://doi.org/10.1371/journal.pone.0197739

Objectives: Pupil light reflex (PLR) has been widely used as a method for evaluating parasympathetic activity. The first aim of the present study is to develop a PLR measurement using a computer screen set-up and compare its results with the PLR gene... Read More about Pupil light reflex evoked by light-emitting diode and computer screen: methodology and association with need for recovery in daily life.

Clinical evidence synopsis: hearing aids and health-related quality of life in adults with hearing loss (2018)
Journal Article
Kitterick, P. T., & Ferguson, M. A. (2018). Clinical evidence synopsis: hearing aids and health-related quality of life in adults with hearing loss. Journal of the American Medical Association, 319(21), https://doi.org/10.1001/jama.2018.5567

Clinical Question Are hearing aids associated with improved health-related quality of life in adults with mild to moderate hearing loss? Bottom Line Compared with no hearing aids, the provision of hearing aids was associated with improveme... Read More about Clinical evidence synopsis: hearing aids and health-related quality of life in adults with hearing loss.