All Outputs (1392)

Effects of cyclic equibiaxial mechanical stretch on ?-BK and TRPV4 expression in equine chondrocytes (2014)
Journal Article

Background Chondrocytes are regularly exposed to load-induced stimuli and have the capability to sense and respond to applied mechanical stress. However, the mechanisms involved in chondrocyte mechanotransduction are not clearly understood. The pu... Read More about Effects of cyclic equibiaxial mechanical stretch on ?-BK and TRPV4 expression in equine chondrocytes.

Acinar cell carcinoma of exocrine pancreas in two horses (2014)
Journal Article

Two horses were presented with non-specific clinical signs of several weeks' duration and were humanely destroyed due to a poor prognosis. At necropsy examination, both horses had multiple small, white nodules replacing pancreatic tissue and involvin... Read More about Acinar cell carcinoma of exocrine pancreas in two horses.

A mitochondrial location for haemoglobins--dynamic distribution in ageing and Parkinson's disease (2014)
Journal Article

Bayesian evaluation of budgets for endemic disease control: an example using management changes to reduce milksomatic cell count early in the first lactation of Irish dairy cows (2014)
Journal Article

The aim of this research was to determine budgets for specific management interventions to control heifer mastitis in Irish dairy herds as an example of evidence synthesis and 1-step Bayesian micro-simulation in a veterinary context. Budgets were det... Read More about Bayesian evaluation of budgets for endemic disease control: an example using management changes to reduce milksomatic cell count early in the first lactation of Irish dairy cows.

Association between somatic cell count during the first lactation and the cumulative milk yield of cows in Irish dairy herds (2014)
Journal Article

Reduced potential milk yield is an important component of mastitis costs in dairy cows. The first aim of this study was to assess associations between somatic cell count (SCC) during the first lactation, and cumulative milk yield over the first lacta... Read More about Association between somatic cell count during the first lactation and the cumulative milk yield of cows in Irish dairy herds.

Survey of the UK veterinary profession: common species and conditions nominated by veterinarians in practice (2014)
Journal Article

The practice of evidence-based veterinary medicine involves the utilisation of scientific evidence for clinical decision making. To enable this, research topics pertinent to clinical practice need to be identified, and veterinary clinicians are best... Read More about Survey of the UK veterinary profession: common species and conditions nominated by veterinarians in practice.

Computed tomography analysis of guinea pig bone: architecture, bone thickness and dimensions throughout development. (2014)
Journal Article

The domestic guinea pig, Cavia aperea f. porcellus, belongs to the Caviidae family of rodents. It is an important species as a pet, a source of food and in medical research. Adult weight is achieved at 8-12 months and life expectancy is ?5-6 years. O... Read More about Computed tomography analysis of guinea pig bone: architecture, bone thickness and dimensions throughout development..

Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012 (2014)
Journal Article

Equine influenza viruses are a major cause of respiratory disease in horses worldwide and undergo antigenic drift. Several outbreaks of equine influenza occurred worldwide during 2010-2012, including in vaccinated animals, highlighting the importance... Read More about Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012.

The impact of cafeteria feeding during lactation in the rat on novel object discrimination in the offspring (2014)
Journal Article

There is increasing evidence that hyperenergetic diets impact on memory in rodents. However, it is largely unknown how diets, such as a cafeteria diet (CD), that mimic a Western diet act on learning and memory, in particular when fed during early sta... Read More about The impact of cafeteria feeding during lactation in the rat on novel object discrimination in the offspring.

The utility of low-density genotyping for imputation in the Thoroughbred horse (2014)
Journal Article

Background Despite the dramatic reduction in the cost of high-density genotyping that has occurred over the last decade, it remains one of the limiting factors for obtaining the large datasets required for genomic studies of disease in the horse. In... Read More about The utility of low-density genotyping for imputation in the Thoroughbred horse.

Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1? (2013)
Journal Article

Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly... Read More about Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1?.

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis (2013)
Journal Article

Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for inte... Read More about IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.

Mycobacteriosis outbreak caused by Mycobacterium aviumsubsp.avium detected through meat inspection in five porcine fattening farms (2013)
Journal Article

Between December 2010 and January 2011 a number (n=20) of cases were submitted to the Slaughterhouse Support Service (Servei de Suport a Escorxadors, SESC-CReSA), consisting of grossly nodular granulomatous and caseous lesions in pig carcasses from f... Read More about Mycobacteriosis outbreak caused by Mycobacterium aviumsubsp.avium detected through meat inspection in five porcine fattening farms.

Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy (2013)
Journal Article

The calculation of pepitope values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the pepitope value to equine influenza vaccine strain selection was assessed. There was a ne... Read More about Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy.

Nanotechnology tracks to the renal ward (2013)
Journal Article

The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages (2013)
Journal Article

There is emerging experimental evidence that hyper-energetic diets not only cause obesity but also impact on behaviour in rodents. A hyper-energetic comfort diet/cafeteria diet (CD) fed during early development programmes anxiety-related behaviour in... Read More about The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages.

Use of contrast-enhanced ultrasonography in chronic pathologic canine testes (2013)
Journal Article

Contrast-enhanced ultrasound with sulphur hexafluoride microbubbles was performed in seven healthy dogs without a history of reproductive pathology and with histologically confirmed normal testes and in 42 dogs with chronic scrotal anomalies. All dog... Read More about Use of contrast-enhanced ultrasonography in chronic pathologic canine testes.

The genetics of virus particle shape in equine influenza A virus (2013)
Journal Article

Background Many human strains of influenza A virus produce highly pleomorphic virus particles that at the extremes can be approximated as either spheres of around 100 nm diameter or filaments of similar cross-section but elongated to lengths of many... Read More about The genetics of virus particle shape in equine influenza A virus.

Behavioural changes in dairy cows with lameness in an automatic milking system (2013)
Journal Article

There is a tendency worldwide for the automation of farms; this has included the introduction of automatic milking systems (AMS) in the dairy industry. Lameness in dairy cows is highly prevalent and painful. These impacts potentially affect not only... Read More about Behavioural changes in dairy cows with lameness in an automatic milking system.

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors (2013)
Journal Article

Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates... Read More about A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.