All Outputs (1392)

The application of eDNA for monitoring of the great crested newt in the UK (2014)
Journal Article

Current ecological surveys for great crested newts are time-consuming and expensive and can only be carried out within a short survey window. Additional survey methods which would facilitate the detection of rare or protected species such as the grea... Read More about The application of eDNA for monitoring of the great crested newt in the UK.

Capturing the complexity of first opinion small animal consultations using direct observation (2014)
Journal Article

Various different methods are currently being used to capture data from small animal consultations. The aim of this study was to develop a tool to record detailed data from consultations by direct observation. A second aim was to investigate the comp... Read More about Capturing the complexity of first opinion small animal consultations using direct observation.

Consultation length in first opinion small animal practice (2014)
Journal Article

Serotonin controlling feeding and satiety (2014)
Journal Article

Serotonin has been implicated in the control of satiety for almost four decades. Historically, the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has stimulated interest in and research into the role of this neuro... Read More about Serotonin controlling feeding and satiety.

Factors affecting phage D29 infection: a tool to investigate different growth states of mycobacteria (2014)
Journal Article

Bacteriophages D29 and TM4 are able to infect a wide range of mycobacteria, including pathogenic and non pathogenic species. Successful phage infection of both fast- and slow-growing mycobacteria can be rapidly detected using the phage amplification... Read More about Factors affecting phage D29 infection: a tool to investigate different growth states of mycobacteria.

The allergenicity of 2S albumin nut proteins: uptake and gene regulation in bmDCs (2014)
Journal Article

Mycobacterium microti Tuberculosis in Its Maintenance Host, the Field Vole (Microtus agrestis): Characterization of the Disease and Possible Routes of Transmission (2014)
Journal Article

Impact of maternal dietary fat supplementation during gestation upon skeletal muscle in neonatal pigs (2014)
Journal Article

Multiple groups of endogenous epsilon-like retroviruses conserved across primates (2014)
Journal Article

Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often describe... Read More about Multiple groups of endogenous epsilon-like retroviruses conserved across primates.

Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification (2014)
Journal Article

It is assumed that sheep and goats consumed the same bovine spongiform encephalopathy (BSE)-contaminated meat and bone meal that was fed to cattle and precipitated the BSE epidemic in the United Kingdom that peaked more than 20 years ago. De- spite i... Read More about Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification.

The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits (2014)
Journal Article

Alcelaphine herpesvirus-1 (AlHV-1) causes malignant catarrhal fever (MCF). The A2 gene of AlHV-1 is a member of the bZIP transcription factor family. We wished to determine whether A2 is a virulence gene or not and whether it is involved in pathogene... Read More about The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits.

Using simulation to interpret a discrete time survival model in a complex biological system: fertility and lameness in dairy cows (2014)
Journal Article

The ever-growing volume of data routinely collected and stored in everyday life presents researchers with a number of opportunities to gain insight and make predictions. This study aimed to demonstrate the usefulness in a specific clinical context of... Read More about Using simulation to interpret a discrete time survival model in a complex biological system: fertility and lameness in dairy cows.

Influenza A Virus Acquires Enhanced Pathogenicity and Transmissibility after Serial Passages in Swine (2014)
Journal Article

Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in pigs. Fu... Read More about Influenza A Virus Acquires Enhanced Pathogenicity and Transmissibility after Serial Passages in Swine.

Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse (2014)
Journal Article

Cytotoxic T-lymphocytes (CTLs) are associated with protective immunity against disease caused by equid herpesvirus type 1 (EHV-1). However, the EHV-1 target proteins for CTLs are poorly defined. This limits the development of vaccine candidates desig... Read More about Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse.

Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development (2014)
Journal Article

This paper identifies a common nutritional pathway relating maternal through to fetal protein-energy malnutrition (PEM) and compromised fetal kidney development. Thirty-one twin-bearing sheep were fed either a control (n=15) or low-protein diet (n=16... Read More about Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development.

Prevalence of Entamoeba species in captive primates in zoological gardens in the UK (2014)
Journal Article

The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology (2014)
Journal Article

1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations, which can sometimes be at low densities and is usually based on visual detection and count... Read More about The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology.

A questionnaire-based survey on the uptake and use of cattle vaccines in the UK (2014)
Journal Article

Background: Vaccination is a widely used strategy for disease control in cattle in the UK and abroad. However, there has been limited research describing the uptake and use of cattle vaccines on UK farms. Aim: To describe the current uptake and usag... Read More about A questionnaire-based survey on the uptake and use of cattle vaccines in the UK.

Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations. (2014)
Journal Article

Changes to the DNA methylome have been described in patients with rheumatoid arthritis (RA). In previous work, we reported genome-wide methylation differences in T-lymphocyte and B-lymphocyte populations from healthy individuals. Now, using HumanMeth... Read More about Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations..

Prospective survey of veterinary practitioners’ primary assessment of equine colic: clinical features, diagnoses, and treatment of 120 cases of large colon impaction (2014)
Journal Article

Background Large colon impactions are a common cause of colic in the horse. There are no scientific reports on the clinical presentation, diagnostic tests and treatments used in first opinion practice for large colon impaction cases. The aim of th... Read More about Prospective survey of veterinary practitioners’ primary assessment of equine colic: clinical features, diagnoses, and treatment of 120 cases of large colon impaction.