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Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature (2017)
Journal Article
Robinson, N. J., Lyons, E., Grindlay, D., & Brennan, M. L. (in press). Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature. Veterinary Sciences, 4(4), https://doi.org/10.3390/vetsci4040058

Rabbits and guinea pigs are increasingly popular pets in the UK, yet little is known about their common ailments, or how these relate to what appears in the published literature. The aim of this study was to characterise the common conditions of rabb... Read More about Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature.

Development and validation of a multiple locus variable number tandem repeat analysis (MLVA) scheme for Fusobacterium necrophorum (2017)
Journal Article
R, C., L E, G., & K J, P. (2018). Development and validation of a multiple locus variable number tandem repeat analysis (MLVA) scheme for Fusobacterium necrophorum. Veterinary Microbiology, 213, 108-113. https://doi.org/10.1016/j.vetmic.2017.11.017

Fusobacterium necrophorum is associated with various diseases in humans and animals. Reservoirs (sites where the pathogen persists in the absence of disease) of F. necrophorum are believed to be present in healthy individuals e.g. tonsillar epitheliu... Read More about Development and validation of a multiple locus variable number tandem repeat analysis (MLVA) scheme for Fusobacterium necrophorum.

Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29 (2017)
Journal Article
Bhandare, S. G., Warry, A., Emes, R. D., Hooton, S. P., Barrow, P. A., & Atterbury, R. J. (2017). Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29. Genome Announcements, 5(46), Article e01013. https://doi.org/10.1128/genomeA.01013-17

The complete genomes of two Vibrio cholerae bacteriophages of potential interest for cholera bacteriophage (phage) therapy were sequenced and annotated. The genome size of phage 24 is 44,395 bp encoding 71 putative proteins, and that of phage X29 is... Read More about Complete Genome Sequences of Vibrio cholerae -Specific Bacteriophages 24 and X29.

Peri-conception and first trimester diet modifies reproductive development in bulls (2017)
Journal Article
Copping, K. J., Ruiz-Diaz, M. D., Rutland, C. S., Mongan, N. P., Callaghan, M., McMillen, I. C., …Perry, V. (in press). Peri-conception and first trimester diet modifies reproductive development in bulls. Reproduction, Fertility and Development, https://doi.org/10.1071/RD17102

Nutritional perturbation during gestation alters male reproductive development in rodents and sheep. In cattle both the developmental trajectory of the feto–placental unit and its response to dietary perturbations is dissimilar to that of these speci... Read More about Peri-conception and first trimester diet modifies reproductive development in bulls.

A comparison of the efficacy of three intervention trial types: postal, group, and one-to-one facilitation, prior management and the impact of message framing and repeat messages on the flock prevalence of lameness in sheep (2017)
Journal Article
Grant, C., Kaler, J., Ferguson, E., O’Kane, H., & Green, L. E. (2018). A comparison of the efficacy of three intervention trial types: postal, group, and one-to-one facilitation, prior management and the impact of message framing and repeat messages on the flock prevalence of lameness in sheep. Preventive Veterinary Medicine, 149, https://doi.org/10.1016/j.prevetmed.2017.11.013

The aim of this study was to evaluate the effectiveness of three knowledge-transfer intervention trial types (postal, group, one-to-one) to promote best practice to treat sheep with footrot. Further aims were to investigate whether farmer behaviour (... Read More about A comparison of the efficacy of three intervention trial types: postal, group, and one-to-one facilitation, prior management and the impact of message framing and repeat messages on the flock prevalence of lameness in sheep.

A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells (2017)
Journal Article
Al-Mayyahi, R. S., Sterio, L. D., Connolly, J. B., Adams, C. F., Al-Tumah, W. A., Sen, J., …Chari, D. M. (2018). A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells. Molecular and Cellular Neuroscience, 86, https://doi.org/10.1016/j.mcn.2017.11.006

Corticosteroids (CSs) are widely used clinically, for example in pediatric respiratory distress syndrome, and immunosuppression to prevent rejection of stem cell transplant populations in neural cell therapy. However, such treatment can be associated... Read More about A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells.

Isolation and evolutionary analysis of Australasian topotype of bluetongue virus serotype 4 from India (2017)
Journal Article
Reddy, Y. V., Susmitha, B., Patil, S., Krishnajyothi, Y., Putty, K., Ramakrishna, K., …Rao, P. (in press). Isolation and evolutionary analysis of Australasian topotype of bluetongue virus serotype 4 from India. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.12738

Bluetongue (BT) is a Culicoides-borne disease caused by several serotypes of bluetongue virus (BTV). Similar to other insect-borne viral diseases, distribution of BT is limited to distribution of Culicoides species competent to transmit BTV. In the t... Read More about Isolation and evolutionary analysis of Australasian topotype of bluetongue virus serotype 4 from India.

Incorporating stakeholder perspectives into the assessment and provision of captive elephant welfare (2017)
Journal Article
Chadwick, C., Williams, E., Asher, L., & Yon, L. (2017). Incorporating stakeholder perspectives into the assessment and provision of captive elephant welfare. Animal Welfare Journal, 26(4), https://doi.org/10.7120/09627286.26.4.461

Recent concerns over the welfare of elephants in UK zoos have implications for their future in captivity, and it is clear that improvements in welfare should be made. Evidence suggests that the knowledge of experienced stakeholders is vital to captiv... Read More about Incorporating stakeholder perspectives into the assessment and provision of captive elephant welfare.

Gene expression profiling of breast tumours from New Zealand patients (2017)
Journal Article
Muthukaruppan, A., Lasham, A., Blenkiron, C., Woad, K. J., Black, M. A., Knowlton, N., …Shelling, A. N. (2017). Gene expression profiling of breast tumours from New Zealand patients. New Zealand Medical Journal, 130(1464), Article 7396

AIMS: New Zealand has one of the highest rates of breast cancer incidence in the world. We investigated the gene expression profiles of breast tumours from New Zealand patients, compared them to gene expression profiles of international breast cancer... Read More about Gene expression profiling of breast tumours from New Zealand patients.

Prevalence of and risk factors for FIV and FeLV infection in two shelters in the United Kingdom (2011-2012) (2017)
Journal Article
Stavisky, J., Dean, R. S., & Molloy, M. H. (in press). Prevalence of and risk factors for FIV and FeLV infection in two shelters in the United Kingdom (2011-2012). Veterinary Record, 181(17), Article 451. https://doi.org/10.1136/vr.103857

The aims of this study were to determine the prevalence of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) infections in cats presented to two RSPCA (Royal Society for the Prevention of Cruelty to Animals) animal rehoming centre... Read More about Prevalence of and risk factors for FIV and FeLV infection in two shelters in the United Kingdom (2011-2012).

Societal sentience: constructions of the public in animal research policy and practice (2017)
Journal Article
Hobson-West, P., & Davies, A. (in press). Societal sentience: constructions of the public in animal research policy and practice. Science, Technology, and Human Values, 43(4), https://doi.org/10.1177/0162243917736138

The use of non-human animals as models in research and drug testing is a key route through which contemporary scientific knowledge is certified. Given ethical concerns, regulation of animal research promotes the use of less ‘sentient’ animals. This p... Read More about Societal sentience: constructions of the public in animal research policy and practice.

Seroprevalence of Toxoplasma gondii infection in arthritis patients in eastern China (2017)
Journal Article
Tian, A., Gu, Y., Zhou, N., Cong, W., Liu, G., Elsheikha, H. M., & Zhu, X. (in press). Seroprevalence of Toxoplasma gondii infection in arthritis patients in eastern China. Infectious Diseases of Poverty, 6, Article 153. https://doi.org/10.1186/s40249-017-0367-2

Background: There is accumulating evidence for an increased susceptibility to infection in patients with arthritis. We sought to understand the epidemiology of Toxoplasma gondii infection in arthritis patients in eastern China, given the paucity of d... Read More about Seroprevalence of Toxoplasma gondii infection in arthritis patients in eastern China.

Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics (2017)
Journal Article
Simpson, S., Dunning, M. D., de Brot, S., Grau-Roma, L., Mongan, N. P., & Rutland, C. S. (2017). Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics. Acta Veterinaria Scandinavica, 59, Article 71. https://doi.org/10.1186/s13028-017-0341-9

Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are 27 times higher than in people. Prognosis in both species is poor, with five year osteosarcoma survival rates in people not having improved in decades. For dogs, o... Read More about Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.

Pharmacokinetics of inorganic cobalt and a vitamin B12 supplement in the thoroughbred horse: differentiating cobalt abuse from supplementation (2017)
Journal Article
Hillyer, L., Ridd, Z., Fenwick, S., Hincks, P., & Paine, S. (2018). Pharmacokinetics of inorganic cobalt and a vitamin B12 supplement in the thoroughbred horse: differentiating cobalt abuse from supplementation. Equine Veterinary Journal, 50(3), 343-349. https://doi.org/10.1111/evj.12774

Background While cobalt is an essential micronutrient for vitamin B12 synthesis in the horse, at supraphysiological concentrations, it has been shown to enhance performance in human subjects and rats, and there is evidence that its administration... Read More about Pharmacokinetics of inorganic cobalt and a vitamin B12 supplement in the thoroughbred horse: differentiating cobalt abuse from supplementation.

Quantitative analysis of antibiotic usage in British sheep flocks (2017)
Journal Article
Davies, P., Remnant, J. G., Green, M. J., Gascoigne, E., Gibbon, N., Hyde, R., …Corbishley, A. (in press). Quantitative analysis of antibiotic usage in British sheep flocks. Veterinary Record, https://doi.org/10.1136/vr.104501

The aim of this study was to examine the variation in antibiotic usage between 207 commercial sheep flocks using their veterinary practice prescribing records. Mean and median prescribed mass per population corrected unit (mg/PCU) was 11.38 and 5.95,... Read More about Quantitative analysis of antibiotic usage in British sheep flocks.

Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference (2017)
Journal Article
Jacquot, M., Nomikou, K., Palmarini, M., Mertens, P., & Biek, R. (2017). Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference. Proceedings of the Royal Society B: Biological Sciences, 284(1864), Article 20170919. https://doi.org/10.1098/rspb.2017.0919

Spatio-temporal patterns of the spread of infectious diseases are commonly driven by environmental and ecological factors. This is particularly true for vector-borne diseases because vector populations can be strongly affected by host distribution as... Read More about Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference.

Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports (2017)
Journal Article
Kovac, M., Litvin, Y. A., Aliev, R. O., Zakirova, E. Y., Rutland, C. S., Kiyasov, A., & Rizvanov, A. A. (2017). Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports. Frontiers in Veterinary Science, 4(168), https://doi.org/10.3389/fvets.2017.00168

In this clinical study, for the first time we used the direct gene therapy to restore severe injuries of the suspensory ligament branch and superficial digital flexor tendon in horses (Equus caballus). We injected the plasmid DNA encoding two therape... Read More about Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports.

Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study (2017)
Journal Article
Wareham, K., Hyde, R., Grindlay, D. J., Brennan, M. L., & Dean, R. S. (2017). Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study. BMC Veterinary Research, 13, Article 295. https://doi.org/10.1186/s12917-017-1207-0

Background Randomised controlled trials (RCTs) are a key component of the veterinary evidence base. Sample sizes and defined outcome measures are crucial components of RCTs. To describe the sample size and number of outcome measures of veterinary... Read More about Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study.

Skull of the grey heron (Ardea cinerea ): detailed investigation of the orbital region (2017)
Journal Article
Bavdek, S., Golob, Z., Janžekovič, F., Rutland, C. S., & Kubale, V. (2017). Skull of the grey heron (Ardea cinerea ): detailed investigation of the orbital region. Anatomia, Histologia, Embryologia, 46(6), 552-557. https://doi.org/10.1111/ahe.12308

The skull of the grey heron (Ardea cinerea) was examined with an emphasis on describing the orbital region. In the young (circa sixteen to seventeen days old) heron, the frontal bone (os frontale) and nasal bone (os nasale) comprised separate paired... Read More about Skull of the grey heron (Ardea cinerea ): detailed investigation of the orbital region.