All Outputs (95)

Impact on weight and glycaemic control in adults with diabetes attending a group- based commercial weight management programme (2017)
Journal Article

Healthcare professionals could work in partnership with commercial group weight management programmes (CGWMP) to help people with diabetes lose weight and improve their glycaemic control. The effect of ongoing CGWMP support on diabetes control has no... Read More about Impact on weight and glycaemic control in adults with diabetes attending a group- based commercial weight management programme.

Allergenicity and oral tolerance of enzymatic cross-linked tropomyosin evaluated using cell and mouse models (2017)
Journal Article

The enzymatic cross-linking of proteins to form high-molecular-weight compounds may alter their sensitization potential. The IgG-/IgE-binding activity, digestibility, allergenicity, and oral tolerance of cross-linked tropomyosin with tyrosinase (CTC)... Read More about Allergenicity and oral tolerance of enzymatic cross-linked tropomyosin evaluated using cell and mouse models.

Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain (2017)
Journal Article

VGF (non-acronymic) was first highlighted to have a role in energy homeostasis through experiments involving dietary manipulation in mice. Fasting increased VGF mRNA in the Arc and levels were subsequently reduced upon refeeding. This anabolic role f... Read More about Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain.

A cross-species gene expression marker-based genetic map and QTL analysis in bambara groundnut (2017)
Journal Article

Bambara groundnut (Vigna subterranea (L.) Verdc.) is an underutilised legume crop, which has long been recognised as a protein-rich and drought-tolerant crop, used extensively in Sub-Saharan Africa. The aim of the study was to identify quantitative t... Read More about A cross-species gene expression marker-based genetic map and QTL analysis in bambara groundnut.

Integrating genetic maps in bambara groundnut [Vigna subterranea (L) Verdc.] and their syntenic relationships among closely related legumes (2017)
Journal Article

Background Bambara groundnut [Vigna subterranea (L) Verdc.] is an indigenous legume crop grown mainly in subsistence and small-scale agriculture in sub-Saharan Africa for its nutritious seeds and its tolerance to drought and poor soils. Given that... Read More about Integrating genetic maps in bambara groundnut [Vigna subterranea (L) Verdc.] and their syntenic relationships among closely related legumes.

Changing plastid dynamics within early root and shoot apical meristem-derived tissue of A. thaliana (2017)
Journal Article

Whilst plastids are fundamental to many aspects of plant biology and the production of enhanced crop cultivars, research into the dynamics of non-green plastids has remained somewhat disregarded by the scientific community compared to chloroplasts. T... Read More about Changing plastid dynamics within early root and shoot apical meristem-derived tissue of A. thaliana.

Using isotope dilution assays to understand speciation changes in Cd, Zn, Pb and Fe in a soil model system under simulated flooding conditions (2017)
Journal Article

Flooded soils are systems with complex chemistry and understanding the mechanisms that control the mobility and bioavailability of metals in these soils is important for their management. This work uses stable metal multi-element isotopic dilution co... Read More about Using isotope dilution assays to understand speciation changes in Cd, Zn, Pb and Fe in a soil model system under simulated flooding conditions.

Identifying seedling root architectural traits associated with yield and yield components in wheat (2017)
Journal Article

Background and Aims: Plant roots growing underground are critical for soil resource acquisition, anchorage and plant-environment interactions. In wheat (Triticum aestivum), however, the target root traits to improve yield potential still remain large... Read More about Identifying seedling root architectural traits associated with yield and yield components in wheat.

Fetal and neonatal exposure to trans fatty acids impacts on susceptibility to atherosclerosis in apolipoprotein E*3 Leiden mice (2017)
Journal Article

Nutrition during pregnancy can impact on the susceptibility of the offspring to cardiovascular disease. Postnatal consumption of trans fatty acids (TFA), associated with partially hydrogenated vegetable oil (PHVO), increases the risk of atheroscleros... Read More about Fetal and neonatal exposure to trans fatty acids impacts on susceptibility to atherosclerosis in apolipoprotein E*3 Leiden mice.

A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion (2017)
Journal Article

Objective: To characterise, as a clinical study, the pharmacokinetics and pharmacodynamics and describe the hypnotic effect of the neurosteroid alfaxalone (3?-hydroxy-5 ?-pregnane-11, 20-dione) formulated with 2-hydroxypropyl-?-cyclodextrin in male a... Read More about A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion.

Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease (2017)
Journal Article

5-methylcytosine and the oxidation product 5-hydroxymethylcytosine are two prominent epigenetic variants of the cytosine base in nuclear DNA of mammalian brains. We measured levels of 5-methylcytosine and 5-hydroxymethylcytosine by enzyme-linked immu... Read More about Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease.

Felix Franks 1926-2016 (2017)
Journal Article

The impact of competition on elephant musth strategies: a game–theoretic model (2017)
Journal Article

Mature male African Savannah elephants are known to periodically enter a temporary state of heightened aggression called “musth,” often linked with increased androgens, particularly testosterone. Sexually mature males are capable of entering musth at... Read More about The impact of competition on elephant musth strategies: a game–theoretic model.

Image-based 3D canopy reconstruction to determine potential productivity in complex multi-species crop systems (2017)
Journal Article

Background and Aims: Intercropping systems contain two or more species simultaneously in close proximity. Due to contrasting features of the component crops, quantification of the light environment and photosynthetic productivity is extremely difficu... Read More about Image-based 3D canopy reconstruction to determine potential productivity in complex multi-species crop systems.

Shared characteristics underpinning C 4 leaf maturation derived from analysis of multiple C 3 and C 4 species of Flaveria (2017)
Journal Article

Most terrestrial plants use C3 photosynthesis to fix carbon. In multiple plant lineages a modified system known as C4 photosynthesis has evolved. To better understand the molecular patterns associated with induction of C4 photosynthesis, the genus Fl... Read More about Shared characteristics underpinning C 4 leaf maturation derived from analysis of multiple C 3 and C 4 species of Flaveria.