Human hippocampal CA3 damage disrupts both recent and remote episodic memories

Miller, Thomas D; Chong, Trevor T-J; Aimola Davies, Anne M.; Johnson, Michael R.; Irani, Sarosh R.; Husain, Masud; Ng, Tammy WC; Jacob, Saiju; Maddison, Paul; Kennard, Christopher; Gowland, Penny A; Rosenthal, Clive R.

doi:10.7554/elife.41836

All Outputs (26)

Cortical thickness and formal thought disorder in schizophrenia: An ultra high-field network-based morphometry study (2020)
Journal Article

Background Persistent formal thought disorder (FTD) is a core feature of schizophrenia. Recent cognitive and neuroimaging studies indicate a distinct mechanistic pathway underlying the persistent positive FTD (pFTD or disorganized thinking), thoug... Read More about Cortical thickness and formal thought disorder in schizophrenia: An ultra high-field network-based morphometry study.

Batch-Mode Clinical-Scale Optical Hyperpolarization of Xenon-129 Using an Aluminum Jacket with Rapid Temperature Ramping (2020)
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We present spin-exchange optical pumping (SEOP) using a third-generation (GEN-3) automated batch-mode clinical-scale 129Xe hyperpolarizer utilizing continuous high-power (∼170 W) pump laser irradiation and a novel aluminum jacket design for rapid tem... Read More about Batch-Mode Clinical-Scale Optical Hyperpolarization of Xenon-129 Using an Aluminum Jacket with Rapid Temperature Ramping.

Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study (2020)
Journal Article

Stimulating the primary motor cortex (M1) using transcranial magnetic stimulation (TMS) causes unique multisensory experience such as the targeted muscle activity, afferent/reafferent sensory feedback, tactile sensation over the scalp and “click” sou... Read More about Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study.

The role of node dynamics in shaping emergent functional connectivity patterns in the brain (2020)
Journal Article

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure–function issue, treating a system of Jansen–Rit neural-mass nodes with... Read More about The role of node dynamics in shaping emergent functional connectivity patterns in the brain.

Measurement of brain lactate during visual stimulation using a long TE semi?LASER sequence at 7 T (2020)
Journal Article

Estimation of metabolic changes during neuronal activation represents a challenge for in vivo MRS, especially for metabolites with low concentration and signal overlap, such as lactate. In this work, we aimed to evaluate the feasibility of detecting... Read More about Measurement of brain lactate during visual stimulation using a long TE semi?LASER sequence at 7 T.

Human hippocampal CA3 damage disrupts both recent and remote episodic memories (2020)
Journal Article

Neocortical-hippocampal interactions support new episodic (event) memories, but there is conflicting evidence about the dependence of remote episodic memories on the hippocampus. In line with systems consolidation and computational theories of episod... Read More about Human hippocampal CA3 damage disrupts both recent and remote episodic memories.