All Outputs (5)

Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo (2019)
Journal Article
Marciani, L., Lopez-Sanchez, P., Pettersson, S., Hoad, C., Abrehart, N., Ahnoff, M., & Strömf, A. (2019). Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo. Food and Function, 10(12), 7892-7899. https://doi.org/10.1039/C9FO01617A

The addition of gelling polysaccharides to sport-drinks may provide improved tolerability of drinks with high concentration of digestible carbohydrates (CHO), otherwise known to increase the risk of gastro-intestinal complaints among athletes under p... Read More about Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo.

Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging (2019)
Journal Article
Lam, C., Sanders, D., Lanyon, P., Garsed, K., Foley, S., Pritchard, S., …Spiller, R. (2019). Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging. United European Gastroenterology Journal, 7(10), 1353-1360. https://doi.org/10.1177/2050640619860372

Background and aims: The regular overnight migrating motor complex (MMC) ensures that the normal fasting small bowel water content (SBWC) is minimised. We have applied our recently validated non-invasive magnetic resonance technique to assess SBWC... Read More about Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging.

A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms in patients with diverticulosis (2019)
Journal Article
Murray, K., Hoad, C., Garratt, J., Kaviani, M., Marciani, L., Smith, J., …Spiller, R. (2019). A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms in patients with diverticulosis. PLoS ONE, 14(5), Article e0216528. https://doi.org/10.1371/journal.pone.0216528

Background Complications of diverticular disease are increasingly common, possibly linked to increasing obesity. Visceral fat could contribute to the development of symptomatic diverticular disease through its pro-inflammatory effects. Objective... Read More about A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms in patients with diverticulosis.

The mechanisms of pharmacokinetic food-drug interactions: A perspective from the UNGAP group (2019)
Journal Article
Koziolek, M., Alcaro, S., Augustijns, P., Basit, A. W., Grimm, M., Hens, B., …Corsetti, M. (2019). The mechanisms of pharmacokinetic food-drug interactions: A perspective from the UNGAP group. European Journal of Pharmaceutical Sciences, 134, 31-59. https://doi.org/10.1016/j.ejps.2019.04.003

The simultaneous intake of food and drugs can have a strong impact on drug release, absorption, distribution, metabolism and/or elimination and consequently, on the efficacy and safety of pharmacotherapy. As such, food-drug interactions are one of th... Read More about The mechanisms of pharmacokinetic food-drug interactions: A perspective from the UNGAP group.

Spatio-Temporal Motility MRI (STMM) analysis of the stomach and colon (2019)
Journal Article
Menys, A., Hoad, C., Spiller, R., Scott, M., Atkinson, D., Marciani, L., & Taylor, S. (2019). Spatio-Temporal Motility MRI (STMM) analysis of the stomach and colon. Neurogastroenterology and Motility, 31(5), https://doi.org/10.1111/nmo.13557

Background: MRI is increasingly used to objectively assess gastrointestinal motility. However, motility metrics often do no not offer insights into the nature of contractile action. This study introduces a systematic method of making spatiotemporal... Read More about Spatio-Temporal Motility MRI (STMM) analysis of the stomach and colon.