All Outputs (6)

Mineralizing Coating on 3D Printed Scaffolds for the Promotion of Osseointegration (2022)
Journal Article
Hasan, A., Bagnol, R., Owen, R., Latif, A., Rostam, H. M., Elsharkawy, S., …Mata, A. (2022). Mineralizing Coating on 3D Printed Scaffolds for the Promotion of Osseointegration. Frontiers in Bioengineering and Biotechnology, 10, Article 836386. https://doi.org/10.3389/fbioe.2022.836386

Design and fabrication of implants that can perform better than autologous bone grafts remain an unmet challenge for the hard tissue regeneration in craniomaxillofacial applications. Here, we report an integrated approach combining additive manufactu... Read More about Mineralizing Coating on 3D Printed Scaffolds for the Promotion of Osseointegration.

An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability (2021)
Journal Article
Wu, Y., Fortunato, G. M., Okesola, B. O., Pellerej Di Brocchetti, F. L., Suntornnond, R., Connelly, J., …Et Al, W. (2021). An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability. Biofabrication, 13(3), Article 035027. https://doi.org/10.1088/1758-5090/abe4c3

Self-assembling bioinks offer the possibility to biofabricate with molecular precision, hierarchical control, and biofunctionality. For this to become a reality with widespread impact, it is essential to engineer these ink systems ensuring reproducib... Read More about An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability.

Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model (2021)
Journal Article
Sennett, M., Friedman, J., Ashley, B., Stoeckl, B., Patel, J., Alini, M., …Dodge, G. (2021). Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model. eCells and Materials Journal, 41, 40-51. https://doi.org/10.22203/ecm.v041a04

The repair of focal cartilage defects remains one of the foremost issues in the field of orthopaedics. Chondral defects may arise from a variety of joint pathologies and left untreated, will likely progress to osteoarthritis. Current repair technique... Read More about Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model.

Peptide-protein coassembling matrices as a biomimetic 3D model of ovarian cancer (2020)
Journal Article
Hedegaard, C. L., Redondo-Gómez, C., Tan, B. Y., Ng, K. W., Loessner, D., & Mata, A. (2020). Peptide-protein coassembling matrices as a biomimetic 3D model of ovarian cancer. Science Advances, 6(40), Article eabb3298. https://doi.org/10.1126/sciadv.abb3298

Bioengineered three-dimensional (3D) matrices expand our experimental repertoire to study tumor growth and progression in a biologically relevant, yet controlled, manner. Here, we used peptide amphiphiles (PAs) to coassemble with and organize extrace... Read More about Peptide-protein coassembling matrices as a biomimetic 3D model of ovarian cancer.

Host-Guest-Mediated Epitope Presentation on Self-Assembled Peptide Amphiphile Hydrogels (2020)
Journal Article
Redondo-Gómez, C., Padilla-Lopategui, S., Azevedo, H. S., & Mata, A. (2020). Host-Guest-Mediated Epitope Presentation on Self-Assembled Peptide Amphiphile Hydrogels. ACS Biomaterials Science and Engineering, 6(9), 4870–4880. https://doi.org/10.1021/acsbiomaterials.0c00549

A key feature in biomaterial design is the incorporation of bioactive signals into artificial constructs to stimulate tissue regeneration. Most currently used hydrogel cell culture systems depend on the covalent attachment of extracellular matrix (EC... Read More about Host-Guest-Mediated Epitope Presentation on Self-Assembled Peptide Amphiphile Hydrogels.

Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures (2020)
Journal Article
Majkowska, A., Redondo-Gómez, C., Rice, A., Gonzalez, M., Inostroza-Brito, K. E., Collin, E., …Mata, A. (2020). Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures. Frontiers in Materials, 7, Article 167. https://doi.org/10.3389/fmats.2020.00167

Multicomponent self-assembly holds great promise for the generation of complex and functional biomaterials with hierarchical microstructure. Here, we describe the use of supramolecular co-assembly between an elastin-like recombinamer (ELR5) and a pep... Read More about Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures.