Anna Majkowska
Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures
Majkowska, Anna; Redondo-G�mez, Carlos; Rice, Alistair; Gonzalez, Mariel; Inostroza-Brito, Karla E; Collin, Estelle; Rodriguez-Cabello, Jose Carlos; Del Rio Hernandez, Armando E.; Solito, Egle; Mata, Alvaro
Authors
Carlos Redondo-G�mez
Alistair Rice
Mariel Gonzalez
Karla E Inostroza-Brito
Estelle Collin
Jose Carlos Rodriguez-Cabello
Armando E. Del Rio Hernandez
Egle Solito
Professor ALVARO MATA A.Mata@nottingham.ac.uk
Chair in Biomedical Engineering & Materials
Contributors
Professor ALVARO MATA A.Mata@nottingham.ac.uk
Other
Abstract
Multicomponent self-assembly holds great promise for the generation of complex and functional biomaterials with hierarchical microstructure. Here, we describe the use of supramolecular co-assembly between an elastin-like recombinamer (ELR5) and a peptide amphiphile (PA) to organise graphene oxide (GO) flakes into bioactive structures across multiple scales. The process takes advantage of a reaction – diffusion mechanism to enable the incorporation and spatial organization of GO within multiple ELR5/PA layers. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ImageJ software were used to demonstrate the hierarchical organisation of GO flakes within the ELR5/PA layers and the distribution profiles of GO throughout the ELR5/PA membranes. Furthermore,atomic force microscopy (AFM) revealed improved Young’s moduli of the ELR5/PA/GOmembranes compared to the ELR5/PA membranes. Lastly, we investigated biocompatibility of the ELR5/PA/GO membrane via various cell culture methods.
Citation
Majkowska, A., Redondo-Gómez, C., Rice, A., Gonzalez, M., Inostroza-Brito, K. E., Collin, E., …Mata, A. (2020). Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures. Frontiers in Materials, 7, Article 167. https://doi.org/10.3389/fmats.2020.00167
Journal Article Type | Article |
---|---|
Acceptance Date | May 6, 2020 |
Online Publication Date | Jun 16, 2020 |
Publication Date | Jun 16, 2020 |
Deposit Date | Jun 5, 2020 |
Publicly Available Date | Mar 29, 2024 |
Journal | Frontiers in Materials |
Electronic ISSN | 2296-8016 |
Publisher | Frontiers Media |
Peer Reviewed | Peer Reviewed |
Volume | 7 |
Article Number | 167 |
DOI | https://doi.org/10.3389/fmats.2020.00167 |
Keywords | graphene oxide, multicomponent self-assembly, peptide amphiphiles, elastin-like recombinamer, hierarchical biomaterials, composite materials |
Public URL | https://nottingham-repository.worktribe.com/output/4582597 |
Publisher URL | https://www.frontiersin.org/articles/10.3389/fmats.2020.00167/full |
Files
Interfacial Self-Assembly
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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