All Outputs (23)

Chemically Labeled Nucleotides and Oligonucleotides Encode DNA for Sensing with Nanopores (2009)
Journal Article
Borsenberger, V., Mitchell, N. J., & Howorka, S. (2009). Chemically Labeled Nucleotides and Oligonucleotides Encode DNA for Sensing with Nanopores. Journal of the American Chemical Society, 131(22), 7530-7531. https://doi.org/10.1021/ja902004s

The labeling of nucleotides and oligonucleotides with reporter groups is an important tool in the sequence-specific sensing of DNA, as exemplified by fluorescence tags. Here we show that chemical tags can encode sequence information for electrical na... Read More about Chemically Labeled Nucleotides and Oligonucleotides Encode DNA for Sensing with Nanopores.

A DNA Nanostructure for the Functional Assembly of Chemical Groups with Tunable Stoichiometry and Defined Nanoscale Geometry (2008)
Journal Article
Mitchell, N., Schlapak, R., Kastner, M., Armitage, D., Chrzanowski, W., Riener, J., …Howorka, S. (2009). A DNA Nanostructure for the Functional Assembly of Chemical Groups with Tunable Stoichiometry and Defined Nanoscale Geometry. Angewandte Chemie International Edition, 48(3), 525-527. https://doi.org/10.1002/anie.200804264

Chemical Tags Facilitate the Sensing of Individual DNA Strands with Nanopores (2008)
Journal Article
Mitchell, N. J., & Howorka, S. (2008). Chemical Tags Facilitate the Sensing of Individual DNA Strands with Nanopores. Angewandte Chemie International Edition, 47(30), 5565-5568. https://doi.org/10.1002/anie.200800183

The base resolution in the detection of single DNA strands with nanopores can be improved by attaching chemical tags to individual bases. Different chemical tags give rise to characteristic current signatures when a DNA molecule passes through a nano... Read More about Chemical Tags Facilitate the Sensing of Individual DNA Strands with Nanopores.