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All Outputs (9)

Case Series: Efficacy of Polyclonal Intravenous Immunoglobulin for Refractory Clostridioides difficile Infection (2024)
Journal Article

Background: Intravenous immunoglobulin (IVIg) for Clostridioides difficile infection (CDI) no longer features in treatment guidelines. However, IVIg is still used by some clinicians for severe or recurrent CDI (rCDI) cases. The main objective of this... Read More about Case Series: Efficacy of Polyclonal Intravenous Immunoglobulin for Refractory Clostridioides difficile Infection.

Pharmacokinetics and safety of fidaxomicin in patients with inflammatory bowel disease and Clostridium difficile infection: An open-label Phase IIIb/IV study (PROFILE) (2018)
Journal Article

©The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. Objectives Inflammatory bowel disease (IBD) poses an increased risk for Clostridium difficile infection (CDI). Fidaxomicin has... Read More about Pharmacokinetics and safety of fidaxomicin in patients with inflammatory bowel disease and Clostridium difficile infection: An open-label Phase IIIb/IV study (PROFILE).

IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c (2015)
Journal Article

We show that IL-36? induced maturation of human MDDCs and stimulated differentiation of IFN-? producing (Type 1) CD3+ lymphocytes but was not as effective as IL-36? in doing so. For the first time, we also show that IL-36? induced expression of CD14... Read More about IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c.