All Outputs (5)

Protease responsive nanoprobes with tethered fluorogenic peptidyl 3-arylcoumarin substrates (2008)
Journal Article

Protease responsive nanosensors were obtained by the attachment of unique green fluorescent bifunctional 3-arylcoumarin-derived fluorogenic substrates to poly(acrylamide-co-N-(3-aminopropyl)methacrylamide) nanoparticles, in which proteolysis results... Read More about Protease responsive nanoprobes with tethered fluorogenic peptidyl 3-arylcoumarin substrates.

A macroporous polymer-supported cyclic anhydride for efficient sequestration of amines (2008)
Journal Article

The efficient removal of primary and secondary amines from organic solutions using a macroporous polymer-supported anhydride is described. The sequestering of primary amines by the anhydride via polymer-bound amide formation is completed within 2-4 h... Read More about A macroporous polymer-supported cyclic anhydride for efficient sequestration of amines.

Differential Recognition of Staphylococcus aureus Quorum-Sensing Signals Depends on Both Extracellular Loops 1 and 2 of the Transmembrane Sensor AgrC (2008)
Journal Article

Virulence in Staphylococcus aureus is regulated via agr-dependent quorum sensing in which an autoinducing peptide (AIP) activates AgrC, a histidine protein kinase. AIPs are usually thiolactones containing seven to nine amino acid residues in which th... Read More about Differential Recognition of Staphylococcus aureus Quorum-Sensing Signals Depends on Both Extracellular Loops 1 and 2 of the Transmembrane Sensor AgrC.

Targeting of polyamidoamine-DNA nanoparticles using the Staudinger ligation: Attachment of an RGD motif either before or after complexation (2008)
Journal Article

Two new methods for the modular synthesis of targeted gene delivery systems are reported. The PEGylated polyamidoamine DMEDA-PEG-DMEDA-(MBA-DMEDA)n+1-PEG-DMEDA 3 was sequentially modified to contain an integrin-binding peptide ligand via the Stauding... Read More about Targeting of polyamidoamine-DNA nanoparticles using the Staudinger ligation: Attachment of an RGD motif either before or after complexation.

Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic (2008)
Journal Article

The increasing resistance of human pathogens to conventional antibiotics presents a growing threat to the chemotherapeutic management of infectious diseases. The lanthionine antibiotics, still unused as therapeutic agents, have recently attracted sig... Read More about Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic.