All Outputs (145)

Comorbidities in patients with gout prior to and following diagnosis: case-control study (2015)
Journal Article

OBJECTIVES: To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis. METHODS: There were 39 111 patients with incident gout and 39 111 matched controls identified fro... Read More about Comorbidities in patients with gout prior to and following diagnosis: case-control study.

Validity of the disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and the Quickdash when used in Dupuytren’s disease (2015)
Journal Article

This study investigated aspects of the validity and reliability of the 30-item Disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and its relationship with the shorter 11-item QuickDASH in patients with Dupuytren’s dis... Read More about Validity of the disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and the Quickdash when used in Dupuytren’s disease.

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families (2015)
Journal Article

IMPORTANCE: Relatives of patients with systemic lupus erythematosus (SLE) appear to be at higher risk of SLE and other autoimmune diseases, but estimates of individual familial risks are largely unavailable or unreliable. Furthermore, relative contri... Read More about Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families.

Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis (2015)
Journal Article

Objective: To examine the association between allopurinol use and all-cause mortality for patients with incident gout. Methods: We compared all-cause mortality in incident gout patients who received allopurinol for at least 6 months within the exp... Read More about Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis.

Global epidemiology of gout: prevalence, incidence and risk factors (2015)
Journal Article

Gout is a crystal-deposition disease that results from chronic elevation of uric acid levels above the saturation point for monosodium urate (MSU) crystal formation. Initial presentation is mainly severely painful episodes of peripheral joint synovit... Read More about Global epidemiology of gout: prevalence, incidence and risk factors.

Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study (2015)
Journal Article

Objective: To investigate familial aggregation of Sjögren's syndrome (SS) and the relative risks (RRs) of other autoimmune disease in relatives of patients with SS. Methods: We identified 23,658,577 beneficiaries enrolled in the Taiwan National Hea... Read More about Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study.

Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study (2015)
Journal Article

© 2015 Muthuri et al.; licensee BioMed Central. Introduction: The aim of this study was to investigate the association between alcoholic and non-alcoholic beverages and knee or hip osteoarthritis (OA). Methods: We conducted a case-control study of Ca... Read More about Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study.

Epidemiology and management of gout in Taiwan: a nationwide population study (2015)
Journal Article

INTRODUCTION: Gout is the most common inflammatory arthritis worldwide and is the only type of chronic arthritis that potentially can be ‘cured’. However, data on gout incidence, prevalence and management, assessed at multiple time points in the same... Read More about Epidemiology and management of gout in Taiwan: a nationwide population study.

Placebos for knee osteoarthritis: Reaffirmation of "Needle is better than pill" (2015)
Journal Article

Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England (2014)
Journal Article

Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant... Read More about Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England.

Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms (2014)
Journal Article

OBJECTIVE: To [1] compare the frequency and severity of ultrasound (US) features in people with normal knees (controls), knee pain (KP), asymptomatic radiographic OA (ROA), and symptomatic OA (SROA), [2] examine relationships between US features, pai... Read More about Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms.

The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012 (2014)
Journal Article

Objectives: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999–2012. Methods: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculate... Read More about The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012.

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article

Introduction Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial (2014)
Journal Article

© 2014, Clinical Rheumatology. This study is aimed at comparing the efficacy and safety of loxoprofen sodium hydrogel patch (LX-P) with loxoprofen sodium tablet (LX-T) in patients with knee osteoarthritis (OA). One hundred sixty-nine patients were en... Read More about Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial.

Ultrasound detected synovial change and pain response following intra-articular injection of corticosteroid and a placebo in symptomatic osteoarthritic knees: a pilot study (2014)
Journal Article

Knee joint stiffness and its relationship with severity of radiographic osteoarthritis, pain and self-reported stiffness (2014)
Journal Article

Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis (2014)
Journal Article

Objective: To identify the optimal exercise program, characterized by type and intensity of exercise, length of program, duration of individual supervised sessions, and number of sessions per week, for reducing pain and patient-reported disability in... Read More about Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan (2013)
Journal Article

© 2015, BMJ Publishing Group. All rights reserved. Objective: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods: Using data from the Nati... Read More about Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study (2013)
Journal Article

© 2015, BMJ Publishing Group. All rights reserved. Objective: Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We e... Read More about The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study.