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Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction (2022)
Journal Article
Bawden, S. J., Hoad, C., Kaye, P., Stephenson, M., Dolman, G., James, M. W., …Aithal, G. P. (2023). Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction. Magnetic Resonance Materials in Physics, Biology and Medicine, 36(4), 553-563. https://doi.org/10.1007/s10334-022-01052-0

Objective: Magnetic resonance spectroscopy (MRS) provides a powerful method of measuring fat fraction. However, previous studies have shown that MRS results give lower values compared with visual estimates from biopsies in fibrotic livers. This study... Read More about Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction.

The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease (2022)
Journal Article
Thapaliya, G., Eldeghaidy, S., Asghar, M., McGing, J., Radford, S., Francis, S., & Moran, G. W. (2022). The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease. Brain Imaging and Behavior, https://doi.org/10.1007/s11682-022-00742-6

Alterations in grey matter volume (GMV) and cortical thickness (CT) in Crohn’s disease (CD) patients has been previously documented. However, the findings are inconsistent, and not a true representation of CD burden, as only CD patients in remission... Read More about The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease.

Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity (2022)
Journal Article
Zhang, J., Najeeb, F., Wang, X., Xu, P., Omer, H., Zheng, J., …Wang, C. (2022). Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity. IEEE Access, 10, 121193-121203. https://doi.org/10.1109/access.2022.3222313

This work presents a free-breathing dynamic contrast-enhanced (DCE) MRI reconstruction method called low-rank plus sparse (L+S) with joint sparsity. The proposed method improved dynamic contrast performance by integrating an additional temporal Fast... Read More about Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity.

Ensemble Kalman inversion for magnetic resonance elastography. (2022)
Journal Article
Iglesias, M., McGrath, D. M., Tretyakov, M. V., & Francis, S. T. (2022). Ensemble Kalman inversion for magnetic resonance elastography. Physics in Medicine and Biology, 67(23), Article 235003. https://doi.org/10.1088/1361-6560/ac9fa1

Magnetic Resonance Elastography (MRE) is an MRI-based diagnostic method for measuring mechanical properties of biological tissues. MRE measurements are processed by an inversion algorithm to produce a map of the biomechanical properties. In this pape... Read More about Ensemble Kalman inversion for magnetic resonance elastography..

Variability of noninvasive MRI and biological markers in compensated cirrhosis: insights for assessing disease progression (2022)
Journal Article
Bradley, C. R., Cox, E. F., Palaniyappan, N., Aithal, G. P., Francis, S. T., & Guha, I. N. (2022). Variability of noninvasive MRI and biological markers in compensated cirrhosis: insights for assessing disease progression. European Radiology Experimental, 6(1), Article 52. https://doi.org/10.1186/s41747-022-00303-y

Abstract: Background: We annually monitored stable compensated cirrhosis (CC) patients to evaluate serial variation in blood serum, liver stiffness, and multiparametric magnetic resonance imaging (mpMRI) measures to provide reference change values (R... Read More about Variability of noninvasive MRI and biological markers in compensated cirrhosis: insights for assessing disease progression.

Fast Event-Related Mapping of Population Fingertip Tuning Properties in Human Sensorimotor Cortex at 7T (2022)
Journal Article
Khalife, S., Francis, S. T., Schluppeck, D., Sánchez-Panchuelo, R. M., & Besle, J. (2022). Fast Event-Related Mapping of Population Fingertip Tuning Properties in Human Sensorimotor Cortex at 7T. eNeuro, 9(5), 1-18. https://doi.org/10.1523/ENEURO.0069-22.2022

fMRI studies that investigate somatotopic tactile representations in the human cortex typically use either block or phase-encoded stimulation designs. Event-related (ER) designs allow for more flexible and unpredictable stimulation sequences than the... Read More about Fast Event-Related Mapping of Population Fingertip Tuning Properties in Human Sensorimotor Cortex at 7T.

Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study (2022)
Journal Article
Luther, T., Eckerbom, P., Cox, E., Lipcsey, M., Bülow, S., Hultström, M., …Liss, P. (2022). Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study. Critical Care, 26(1), 262. https://doi.org/10.1186/s13054-022-04132-8

Abstract: Background: Renal hypoperfusion has been suggested to contribute to the development of acute kidney injury (AKI) in critical COVID-19. However, limited data exist to support this. We aim to investigate the differences in renal perfusion, ox... Read More about Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study.

LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint (2022)
Journal Article
Jafari, M., Francis, S., Garibaldi, J. M., & Chen, X. (2022). LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint. Medical Image Analysis, 81, Article 102536. https://doi.org/10.1016/j.media.2022.102536

In medical image segmentation, supervised machine learning models trained using one image modality (e.g. computed tomography (CT)) are often prone to failure when applied to another image modality (e.g. magnetic resonance imaging (MRI)) even for the... Read More about LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint.

Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease (2022)
Journal Article
Makvandi, K., Hockings, P. D., Jensen, G., Unnerstall, T., Leonhardt, H., Jarl, L. V., …Baid-Agrawal, S. (2022). Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease. Clinical Kidney Journal, 15(7), 1387–1402. https://doi.org/10.1093/ckj/sfac054

Background: We sought to develop a novel non-contrast multiparametric MRI (mpMRI) protocol employing several complementary techniques in a single scan session for a comprehensive functional and structural evaluation of diabetic kidney disease (DKD).... Read More about Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease.