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Ensemble Kalman inversion for magnetic resonance elastography.

Iglesias, Marco; McGrath, Deirdre M.; Tretyakov, M. V.; Francis, Susan T

Ensemble Kalman inversion for magnetic resonance elastography. Thumbnail


Deirdre M. McGrath


Magnetic Resonance Elastography (MRE) is an MRI-based diagnostic method for measuring mechanical properties of biological tissues. MRE measurements are processed by an inversion algorithm to produce a map of the biomechanical properties. In this paper a new and powerful method (Ensemble Kalman Inversion with Level Sets (EKI)) of MRE inversion is proposed and tested. The method has critical advantages: material property variation at disease boundaries can be accurately identified, and uncertainty of the reconstructed material properties can be evaluated by consequence of the probabilistic nature of the method. EKI is tested in 2D and 3D experiments with synthetic MRE data of the human kidney. It is demonstrated that the proposed inversion method is accurate and fast.


Iglesias, M., McGrath, D. M., Tretyakov, M. V., & Francis, S. T. (2022). Ensemble Kalman inversion for magnetic resonance elastography. Physics in Medicine and Biology, 67(23), Article 235003.

Journal Article Type Article
Acceptance Date Nov 1, 2022
Online Publication Date Nov 2, 2022
Publication Date Dec 7, 2022
Deposit Date Nov 11, 2022
Publicly Available Date Nov 17, 2022
Journal Physics in Medicine and Biology
Print ISSN 0031-9155
Electronic ISSN 1361-6560
Publisher IOP Publishing
Peer Reviewed Peer Reviewed
Volume 67
Issue 23
Article Number 235003
Keywords Radiology, Nuclear Medicine and imaging; Radiological and Ultrasound Technology
Public URL
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