Mast Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis

Babaei-Jadidi, Roya; Dongre, Arundhati; Miller, Suzanne; Castellanos Uribe, Marcos; Stewart, Iain D.; Thompson, Zoe M; Nateri, Abdolrahman S.; Bradding, Peter; May, Sean T.; Clements, Debbie; Johnson, Simon R

doi:10.1164/rccm.202007-2854OC

All Outputs (2)

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) (2021)
Journal Article

Introduction The COVID-19 pandemic has led to over 100 million cases worldwide. The UK has had over 4 million cases, 400 000 hospital admissions and 100 000 deaths. Many patients with COVID-19 suffer long-term symptoms, predominantly breathlessness a... Read More about Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID).

Mast Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis (2021)
Journal Article

Rationale: Lymphangioleiomyomatosis (LAM) is a multisystem disease that causes lung cysts and respiratory failure. Loss of TSC (tuberous sclerosis complex) gene function results in a clone of “LAM cells” with dysregulated mTOR (mechanistic target of... Read More about Mast Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis.