All Outputs (6)

A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium (2012)
Journal Article

Background: Lymphovascular invasion (LVI) is an important step in the metastatic cascade; tumor cell migration and adhesion to blood and lymphatic vessels is followed by invasion through the vessel wall and subsequent systemic spread. Although prim... Read More about A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium.

Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla (2012)
Journal Article

Background: Pancreatic cancer, including cancer of the ampulla of Vater and bile duct, is very aggressive and has a poor five year survival rate; improved methods of patient stratification are required. Methods: We assessed the expression of calpai... Read More about Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla.

Calpain-2 expression is associated with response to platinum based chemotherapy, progression-free and overall survival in ovarian cancer (2012)
Journal Article

Ovarian cancer is routinely treated with surgery and platinum-based chemotherapy. Resistance is a major obstacle in the efficacy of this chemotherapy regimen and the ability to identify those patients at risk of developing resistance is of considera... Read More about Calpain-2 expression is associated with response to platinum based chemotherapy, progression-free and overall survival in ovarian cancer.

Calpain system protein expression in basal-like and triple-negative invasive breast cancer (2012)
Journal Article

Background: Basal-like and triple-negative breast tumours encompass an important clinical subgroup and biomarkers that can prognostically stratify these patients are required. Materials and methods: We investigated two breast cancer tissue microarr... Read More about Calpain system protein expression in basal-like and triple-negative invasive breast cancer.

The prognostic and predictive power of redox rotein expression for anthracycline-based chemotherapy response in locally advanced breast cancer (2012)
Journal Article

Neoadjuvant chemotherapy has become the standard of care for locally advanced primary breast cancer. Anthracycline-based regimens have proven to be one of the most effective treatments in this setting. As certain cytotoxic antineoplastic agents, such... Read More about The prognostic and predictive power of redox rotein expression for anthracycline-based chemotherapy response in locally advanced breast cancer.

Base Excision Repair, the Redox Environment and Therapeutic Implications (2012)
Journal Article

Control of redox homeostasis is crucial for a number of cellular processes with deregulation leading to a number of serious consequences including oxidative damage such induction of DNA base lesions. The DNA lesions caused by oxidative damage are pri... Read More about Base Excision Repair, the Redox Environment and Therapeutic Implications.