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All Outputs (25)

A surrogate model for the economic evaluation of renewable hydrogen production from biomass feedstocks via supercritical water gasification (2023)
Journal Article

Supercritical water gasification is a promising technology for renewable hydrogen production from high moisture content biomass. This work produces a machine learning surrogate model to predict the Levelised Cost of Hydrogen over a range of biomass c... Read More about A surrogate model for the economic evaluation of renewable hydrogen production from biomass feedstocks via supercritical water gasification.

Bayesian and ultrasonic sensor aided multi-objective optimisation for sustainable clean-in-place processes (2023)
Journal Article

In food and drink manufacturing, clean-in-place procedures are essential for hygienic and efficient operations but often over-clean process equipment leading to unnecessary use of energy, water, and chemicals. Previous attempts in the literature to o... Read More about Bayesian and ultrasonic sensor aided multi-objective optimisation for sustainable clean-in-place processes.

Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics (2023)
Journal Article

Objective: To implement complex, PINCER (pharmacist led information technology intervention) prescribing indicators, on a national scale with general practice data to describe the impact of the covid-19 pandemic on safe prescribing. Design: Popula... Read More about Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics.

Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5 (2022)
Journal Article

Background: Injuries in children aged under 5 years most commonly occur in the home and disproportionately affect those living in the most disadvantaged communities. The 'Safe at Home' (SAH) national home safety equipment scheme, which ran in England... Read More about Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5.

Scaling-up a pharmacist-led information technology intervention (PINCER) to reduce hazardous prescribing in general practices: Multiple interrupted time series study (2022)
Journal Article

Background: We previously reported on a randomised trial demonstrating the effectiveness and cost-effectiveness of a pharmacist-led information technology intervention (PINCER). We sought to investigate whether PINCER was effective in reducing hazard... Read More about Scaling-up a pharmacist-led information technology intervention (PINCER) to reduce hazardous prescribing in general practices: Multiple interrupted time series study.

Reconciling the sustainable manufacturing of commodity chemicals with feasible technoeconomic outcomes: Assessing the investment case for heat integrated aerobic gas fermentation (2021)
Journal Article

The manufacturing industry must diverge from a ‘take, make and waste’ linear production paradigm towards more circular economies. Truly sustainable, circular economies are intrinsically tied to renewable resource flows, where vast quantities need to... Read More about Reconciling the sustainable manufacturing of commodity chemicals with feasible technoeconomic outcomes: Assessing the investment case for heat integrated aerobic gas fermentation.

Incidence, nature and causes of avoidable significant harm in primary care in England: retrospective case note review (2020)
Journal Article

Objective To estimate the incidence of avoidable significant harm in primary care in England; describe and classify the associated patient safety incidents and generate suggestions to mitigate risks of ameliorable factors contributing to the incident... Read More about Incidence, nature and causes of avoidable significant harm in primary care in England: retrospective case note review.

Processing discharge summaries in general practice: a qualitative interview study with GPs and practice managers (2019)
Journal Article

Background Discharge summaries are essential for communicating patient information from secondary care to general practice on hospital discharge. Although there has been extensive research into their design and completion in secondary care very l... Read More about Processing discharge summaries in general practice: a qualitative interview study with GPs and practice managers.

Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study (2018)
Journal Article

Background: Polypharmacy is an increasing challenge for primary care. Although sometimes clinically justified, polypharmacy can be inappropriate, leading to undesirable outcomes. Optimising care for polypharmacy necessitates effective targeting and m... Read More about Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study.

Understanding the implementation and adoption of an information technology intervention to support medicine optimisation in primary care: qualitative study using strong structuration theory (2017)
Journal Article

Objectives: Using strong structuration theory, we aimed to understand the adoption and implementation of an electronic clinical audit and feedback tool to support medicine optimisation for patients in primary care. Design: This is a qualitative st... Read More about Understanding the implementation and adoption of an information technology intervention to support medicine optimisation in primary care: qualitative study using strong structuration theory.

Understanding the implementation and adoption of a technological intervention to improve medication safety in primary care: a realist evaluation (2017)
Journal Article

Background: Monitoring for potentially hazardous prescribing is increasingly important to improve medication safety. Healthcare information technology can be used to achieve this aim, for example by providing access to prescribing data through survei... Read More about Understanding the implementation and adoption of a technological intervention to improve medication safety in primary care: a realist evaluation.

Understanding the epidemiology of avoidable significant harm in primary care: protocol for a retrospective cross-sectional study (2017)
Journal Article

Introduction: Most patient safety research has focused on specialist-care settings where there is an appreciation of the frequency and causes of medical errors, and the resulting burden of adverse events. There have, however, been few large-scale rob... Read More about Understanding the epidemiology of avoidable significant harm in primary care: protocol for a retrospective cross-sectional study.

Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink (2015)
Journal Article

Study question: What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices? Methods: A cross sectional study included all adult patients pot... Read More about Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink.

Primary Care Medication Safety Surveillance with Integrated Primary and Secondary Care Electronic Health Records: A Cross-Sectional Study (2015)
Journal Article

Introduction: The extent of preventable medication-related hospital admissions and medication-related issues in primary care is significant enough to justify developing decision support systems for medication safety surveillance. The prerequisite for... Read More about Primary Care Medication Safety Surveillance with Integrated Primary and Secondary Care Electronic Health Records: A Cross-Sectional Study.