All Outputs (4)

Untargeted analysis of plasma samples from pre-eclamptic women reveals polar and apolar changes in the metabolome (2019)
Journal Article
Sander, K. N., Kim, D., Ortori, C. A., Warren, A. Y., Anyanwagu, U. C., Hay, D. P., …Barrett, D. A. (2019). Untargeted analysis of plasma samples from pre-eclamptic women reveals polar and apolar changes in the metabolome. Metabolomics, 15, 1-10. https://doi.org/10.1007/s11306-019-1600-8

Introduction Pre-eclampsia is a hypertensive gestational disorder that affects approximately 5% of all pregnancies. Objectives As the pathophysiological processes of pre-eclampsia are still uncertain, the present case–control study explored unde... Read More about Untargeted analysis of plasma samples from pre-eclamptic women reveals polar and apolar changes in the metabolome.

Expression of cholesterol packaging and transport genes in human and rat placenta: impact of obesity and a high-fat diet (2019)
Journal Article
Draycott, S. A., Daniel, Z., Khan, R., Muhlhausler, B. S., & Langley-Evans, S. C. (2019). Expression of cholesterol packaging and transport genes in human and rat placenta: impact of obesity and a high-fat diet. Journal of Developmental Origins of Health and Disease, 11(3), 222-227. https://doi.org/10.1017/S2040174419000606

Evidence suggests that sub-optimal maternal nutrition has implications for the developing offspring. We have previously shown that exposure to a low-protein diet during gestation was associated with upregulation of genes associated with cholesterol t... Read More about Expression of cholesterol packaging and transport genes in human and rat placenta: impact of obesity and a high-fat diet.

Pharmacological profile of vascular activity of human stem villous arteries (2019)
Journal Article
Sander, K. N., Ali, T. Y., Warren, A. Y., Hay, D. P., Broughton Pipkin, F., Barrett, D. A., & Khan, R. N. (2019). Pharmacological profile of vascular activity of human stem villous arteries. Placenta, 88, 12-19. https://doi.org/10.1016/j.placenta.2019.09.009

© 2019 Introduction: The function of the placental vasculature differs considerably from other systemic vascular beds of the human body. A detailed understanding of the normal placental vascular physiology is the foundation to understand perturbed co... Read More about Pharmacological profile of vascular activity of human stem villous arteries.

Excess androgen production in subcutaneous adipose tissue of women with polycystic ovarian syndrome (2019)
Journal Article
Amer, S. A., Alzanati, N. G., Warren, A., Tarbox, R., & Khan, R. (2019). Excess androgen production in subcutaneous adipose tissue of women with polycystic ovarian syndrome. Journal of Endocrinology, 241(1), 99-109. https://doi.org/10.1530/JOE-18-0674

© 2019 Society for Endocrinology Published by Bioscientifica Ltd. The purpose of this study was to investigate androgen production and the role of insulin and LH in its regulation in subcutaneous adipose tissue (SAT) of women with polycystic ovarian... Read More about Excess androgen production in subcutaneous adipose tissue of women with polycystic ovarian syndrome.