All Outputs (13)
Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis (2009)
Journal Article
Background and Purpose: High blood pressure (BP) is common in acute ischemic stroke and associated independently with a poor functional outcome. However, the management of BP acutely remains unclear because no large trials have been completed. Metho... Read More about Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis.
Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review (2009)
Journal Article
Background: Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke. Methods: Relevant studies were identified with searches of Medline, Embase and... Read More about Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review.
Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression (2009)
Journal Article
Both low and high blood pressure (BP) during the acute phase of stroke are associated independently with a poor outcome. Several small clinical trials have involved the alteration of BP and this study assessed the relationship between change in BP an... Read More about Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression.
Antiplatelet activity should be measured routinely: no (2009)
Journal Article
Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration (2009)
Journal Article
Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Methods... Read More about Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration.
Thigh-length compression stockings and DVT after stroke (2009)
Journal Article
Speeding stroke recovery? A systematic review of amphetamine after stroke (2009)
Journal Article
Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke. Methods: Elec... Read More about Speeding stroke recovery? A systematic review of amphetamine after stroke.
Need for ethics approval and patient consent in clinical research (2009)
Journal Article
Interventions for deliberately altering blood pressure in acute stroke (2009)
Journal Article
Good laboratory practice: preventing introduction of bias at the bench (2009)
Journal Article
Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review—Accumulating evidence sugge... Read More about Good laboratory practice: preventing introduction of bias at the bench.
The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2009)
Journal Article
Background and Purpose—High blood pressure (BP) is present in 80% of patients with acute ischemic stroke and is independently associated with poor outcome. There are few data examining the relationship between admission BP and acute CT findings. M... Read More about The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).
Systematic reviews as a tool for planning and interpreting trials (2009)
Journal Article
Background Systematic reviews followed by ameta-analysis are carried out in medical research to combine the results of two or more related studies. Stroke trials have struggled to show beneficial effects and meta-analysis should be used more widely... Read More about Systematic reviews as a tool for planning and interpreting trials.