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All Outputs (13)

A novel dietary intervention reduces circulatory branched-chain amino acids by 50%: A pilot study of relevance for obesity and diabetes (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Elevated circulating branched-chain amino acids (BCAAs; isoleucine, leucine, and valine) are associated with obesity and type 2 diabetes (T2D). Reducing circulatory BCAAs by dietary restrictio... Read More about A novel dietary intervention reduces circulatory branched-chain amino acids by 50%: A pilot study of relevance for obesity and diabetes.

The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo (2020)
Journal Article

Key points: Reduced vitamin D receptor (VDR) expression prompts skeletal muscle atrophy. Atrophy occurs through catabolic processes, namely the induction of autophagy, while anabolism remains unchanged. In response to VDR-knockdown mitochondrial func... Read More about The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo.

Molecular and neural adaptations to neuromuscular electrical stimulation; Implications for ageing muscle (2020)
Journal Article

One of the most notable effects of ageing is an accelerated decline of skeletal muscle mass and function, resulting in various undesirable outcomes such as falls, frailty, and all-cause mortality. The loss of muscle mass directly leads to functional... Read More about Molecular and neural adaptations to neuromuscular electrical stimulation; Implications for ageing muscle.

Influence of sex on the age?related adaptations of neuromuscular function and motor unit properties in elite masters athletes (2020)
Journal Article

Motor unit (MU) remodelling acts to minimise loss of muscle fibres following denervation in older age, which may be more successful in masters athletes. Evidence suggests performance and neuromuscular function decline with age in this population, alt... Read More about Influence of sex on the age?related adaptations of neuromuscular function and motor unit properties in elite masters athletes.

Associations between plasma branched chain amino acids and health biomarkers in response to resistance exercise training across age (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Leucine, isoleucine and valine (i.e., the branched chain amino acids, BCAA) play a key role in the support and regulation of tissue protein regulation and also as energy substrates. However, p... Read More about Associations between plasma branched chain amino acids and health biomarkers in response to resistance exercise training across age.

Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single nucleotide polymorphisms in elite masters athletes (2020)
Journal Article

Recent large genome-wide association studies (GWAS) have independently identified a set of genetic loci associated with lean body mass (LBM) and handgrip strength (HGS). Evaluation of these candidate single nucleotide polymorphisms (SNPs) may be usef... Read More about Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single nucleotide polymorphisms in elite masters athletes.

The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men (2020)
Journal Article

Background: The aim of this study was to investigate the effect of whey protein supplementation on myofibrillar protein synthesis (myoPS) and muscle recovery over a 7-d period of intensified resistance training (RT). Methods: In a double-blind random... Read More about The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men.

High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomised control trial (2020)
Journal Article

Objectives To assess the efficacy of high-intensity interval training (HIIT) for improving cardiorespiratory fitness (CRF) in patients awaiting resection for urological malignancy within four weeks. Subjects/patients and methods A randomised... Read More about High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomised control trial.

Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass, Strength and Function in Healthy Adults: A Systematic Review (2020)
Journal Article

Background: The prevalence of vascular dysfunction increases with advancing age, as does the loss of muscle mass, strength and function. This systematic review explores the association between vascular dysfunction and skeletal muscle health in health... Read More about Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass, Strength and Function in Healthy Adults: A Systematic Review.