All Outputs (10)

A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes. (2023)
Journal Article

Background People with cystic fibrosis (CF) can experience recurrent chest infections, pancreatic exocrine insufficiency and gastrointestinal symptoms. New cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs improve lung fun... Read More about A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes..

The Potential of Low-Field-Strength MRI for Simpler Fetal Scanning (2023)
Journal Article

The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T (2023)
Journal Article

Parallel transmit MRI at 7 T has increasingly been adopted in research projects and provides increased signal‐to‐noise ratios and novel contrasts. However, the interactions of fields in the body need to be carefully considered to ensure safe scanning... Read More about The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T.

In vivo observation of a stomach road or ‘Magenstrasse’ for gastric emptying using MRI imaging in healthy humans (2023)
Journal Article

The presence of a ‘magenstrasse’, a central ‘stomach road’ for flow and mixing of foods and drinks in the stomach had been predicted from hydrodynamic modelling. Here a magnetic resonance imaging (MRI) tagging technique was used to gain novel insight... Read More about In vivo observation of a stomach road or ‘Magenstrasse’ for gastric emptying using MRI imaging in healthy humans.

Measuring chemical exchange saturation transfer exchange rates in the human brain using a particle swarm optimisation algorithm (2023)
Journal Article

The z‐spectrum contains many pools with different exchange rates and T 2 values, which can make it difficult to interpret in vivo data and complicates the design of experiments aimed at providing sensitivity to one pool. This work aims to characteris... Read More about Measuring chemical exchange saturation transfer exchange rates in the human brain using a particle swarm optimisation algorithm.

MRI tagging of colonic chyme mixing in healthy subjects: Inter‐observer variability and reliability of the measurement with time (2023)
Journal Article

Background: Magnetic resonance imaging (MRI) tagging techniques have been applied to the GI tract to assess bowel contractions and content mixing. We aimed to evaluate the dependence of a tagging measurement (for assessing chyme mixing) on inter-obse... Read More about MRI tagging of colonic chyme mixing in healthy subjects: Inter‐observer variability and reliability of the measurement with time.

A shared neural basis underlying psychiatric comorbidity (2023)
Journal Article

Recent studies proposed a general psychopathology factor underlying common comorbidities among psychiatric disorders. However, its neurobiological mechanisms and generalizability remain elusive. In this study, we used a large longitudinal neuroimagin... Read More about A shared neural basis underlying psychiatric comorbidity.

Trajectories of cortical structures associated with stress across adolescence: a bivariate latent change score approach (2023)
Journal Article

Background: Stress exposure in childhood and adolescence has been linked to reductions in cortical structures and cognitive functioning. However, to date, most of these studies have been cross-sectional, limiting the ability to make long-term inferen... Read More about Trajectories of cortical structures associated with stress across adolescence: a bivariate latent change score approach.

Conduct problems are associated with accelerated thinning of emotion-related cortical regions in a community-based sample of adolescents (2023)
Journal Article

Few studies have examined the association between conduct problems and cerebral cortical development. Herein, we characterize the association between age-related brain change and conduct problems in a large longitudinal, community-based sample of ado... Read More about Conduct problems are associated with accelerated thinning of emotion-related cortical regions in a community-based sample of adolescents.

Liver glycogen stores via 13C magnetic resonance spectroscopy in healthy children: randomized, controlled study (2023)
Journal Article

Background: Owing to its role in glucose homeostasis, liver glycogen concentration ([LGly]) can be a marker of altered metabolism seen in disorders that impact the health of children. However, there is a paucity of normative data for this measure in... Read More about Liver glycogen stores via 13C magnetic resonance spectroscopy in healthy children: randomized, controlled study.